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Increasing extracellular H2O2 produces a bi-phasic response in intracellular H2O2with peroxiredoxin hyperoxidation only triggered once the cellular H2O2-buffering capacity is overwhelmed

Lookup NU author(s): Lewis Tomalin, Dr Alison Day, Zoe Underwood, Dr Graham Smith, Dr Piero Dalle Pezze, Waseema Patel, Dr Daryl Shanley, Dr Elizabeth Veal

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This work is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).


Publication metadata

Author(s): Tomalin LE, Day AM, Underwood ZE, Smith GR, Dalle Pezze P, Rallis C, Patel W, Dickinson BC, Bähler J, Brewer TF, Chang CJ-L, Shanley DP, Veal EA

Publication type: Article

Publication status: Published

Journal: Free Radicals in Biology and Medicine

Year: 2016

Volume: 95

Pages: 333-348

Print publication date: 01/06/2016

Online publication date: 02/03/2016

Acceptance date: 29/02/2016

Date deposited: 17/03/2016

ISSN (print): 0891-5849

ISSN (electronic): 1873-4596

Publisher: Elsevier

URL: http://dx.doi.org/10.1016/j.freeradbiomed.2016.02.035

DOI: 10.1016/j.freeradbiomed.2016.02.035

PubMed id: 26944189


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Funding

Funder referenceFunder name
095598/Z/11/ZWellcome Trust Senior Investigator Award
BB/F015895/1BBSRC
BB/F016980/1BBSRC
BB/F023065/1BBSRC
GM 79465NIH
T32 GM066698National Institutes of Health
BB/F015895/1

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