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Derivation of a system-independent Ki for Pgp-mediated digoxin transport from system-dependent IC₅₀ data by accounting for the contribution of additional digoxin transporters

Lookup NU author(s): Dr Git Chung, Dr Colin Brown

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Author(s): Chaudhry A, Chung G, Lynn A, Yalvigi A, Brown C, Ellens H, O'Connor M, Lee C, Bentz J

Publication type: Article

Publication status: Published

Journal: Drug Metabolism and Disposition

Year: 2018

Volume: 46

Issue: 3

Pages: 279-290

Print publication date: 01/03/2018

Online publication date: 09/01/2018

Acceptance date: 02/04/2016

Date deposited: 22/01/2018

ISSN (print): 0090-9556

ISSN (electronic): 1521-009X

Publisher: American Society for Pharmacology and Experimental Therapeutics

URL: https://doi.org/10.1124/dmd.117.075606

DOI: 10.1124/dmd.117.075606

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