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Browsing publications by Professor John Simpson.

Newcastle AuthorsTitleYearFull text
Daniel Brooks
Dr Stephen Wright
Dr Nadia Mcallister
Dr Sara Graziadio
Dr John Davidson
et al.
Assessment of the comparative agreement between chest radiographs and CT scans in intensive care units2024
Dr Ian Forrest
Professor John Simpson
Real-world experience of nintedanib for progressive fibrosing interstitial lung disease in the UK2024
Professor John Simpson
Reply: Research Bronchoscopy Standards and the Need for Noninvasive Sampling of the Failing Lungs2024
Professor John Simpson
Dr Jo Elverson
Dr Vicky Ewan
Dr Hilary Tedd
Dr Rhys Thomas
et al.
BTS clinical statement on aspiration pneumonia2023
Dr Morag Andrew
Dr Jo Elverson
Dr Hilary Tedd
Professor John Simpson
BTS Clinical Statement on the prevention and management of community-acquired pneumonia in people with learning disability2023
Sarah Thompson
Chong Pang
Dr Tom Hellyer
Dr Jonathan Scott
Professor John Simpson
et al.
Nitration of Chemokine CXCL8 acts as a natural mechanism to limit acute inflammation2023
Dr Jon Murray
Dr Cameron Williams
Dr Clare Lendrem
Amanda Winter
Professor John Simpson
et al.
Patient Self-Testing of Kidney Function at Home, a Prospective Clinical Feasibility Study in Kidney Transplant Recipients2023
Zeynep Elcioglu
Linda Errington
Bogdan Metes
Dr Wezi Sendama
Jason Powell
et al.
Pooled prevalence of lymphopenia in all-cause hospitalisations and association with infection: a systematic review and meta-analysis2023
Dr Nicola Hall
Dr Nikki Rousseau
David Hamilton
Professor John Simpson
Steven Powell
et al.
Providing care for children with tracheostomies: a qualitative interview study with parents and health professionals2023
Dr Kathryn Musgrave
Dr Jonathan Scott
Dr Wezi Sendama
Aaron Gardner
Fiona Dewar
et al.
Tissue factor expression in monocyte subsets during human immunothrombosis, endotoxemia and sepsis2023
Dr Wezi Sendama
Dr Wendy Funston
Dr Anthony Rostron
Professor John Simpson
Tissue-Resident Memory T Cells Are Implicated in the Pathogenesis of Hypersensitivity Pneumonitis2023
Jason Powell
Steven Powell
Michael Mather
Lauren Beck
Dr Pawel Palmowski
et al.
Tracheostomy in children is associated with neutrophilic airway inflammation2023
Dr Wendy Funston
Dr Marie-Helene Ruchaud
Jonathan Scott
Jason Powell
Dr Faye Cooles
et al.
A human model of bilateral pulmonary vein sampling to assess the effects of one-lung ventilation on neutrophil function2022
Dr Jose Luis Marin-Rubio
Dr Maria Duenas Fadic
Dr Tiaan Heunis
Dr Abeer Dannoura
Dr Joe Inns
et al.
A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia2022
Dr Kathryn Musgrave
Dr Jonathan Scott
Dr Anthony Rostron
Professor John Simpson
Author Correction: Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation (Nature Immunology, (2022), 23, 6, (927-939), 10.1038/s41590-022-01216-z)2022
Dr Nicola Hall
David Hamilton
Professor John Simpson
Steven Powell
Dr Malcolm Brodlie
et al.
Impact of COVID-19 on carers of children with tracheostomies2022
Dr Wezi Sendama
Professor John Simpson
Dr Vicky Ewan
Severe hospital-acquired pneumonia2022
Dr Anthony Rostron
Jonathan Scott
Professor John Simpson
Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF152021
Professor John Simpson
Core Outcome Measures for Trials in People With Coronavirus Disease 2019: Respiratory Failure, Multiorgan Failure, Shortness of Breath, and Recovery2021
Catherine Hatton
Dr Rachel Botting
Dr Maria Duenas Fadic
Dr Iram Haq
Dr Bernard Verdon
et al.
Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-22021
Jonathan Scott
Dr Marie-Helene Ruchaud
Dr Kate Musgrave
Dr Stephen Wright
Dr John Perry
et al.
Phosphoinositide 3-kinase δ inhibition improves neutrophil bacterial killing in critically ill patients at high risk of infection2021
Dr Benjamin Pippard
Dr Mary Neal
Dr Kieren Hollingsworth
Dr Holly Fisher
Professor John Matthews
et al.
Reproducibility of 19F-MR ventilation imaging in healthy volunteers2021
Professor John Simpson
Understanding the burden of interstitial lung disease post-COVID-19: The UK Interstitial Lung Disease-Long COVID Study (UKILD-Long COVID)2021
Dr Tom Hellyer
Dr Stephen Wright
Dr Simon Baudouin
Dr Anthony Rostron
Jonathan Scott
et al.
Biomarker-guided antibiotic stewardship in suspected ventilator-associated pneumonia (VAPrapid2): a randomised controlled trial and process evaluation2020
Dr Marie-Helene Ruchaud
Jonathan Scott
Professor John Simpson
C5a impairs phagosomal maturation in the neutrophil through phosphoproteomic remodeling2020
Professor John Simpson
Contrasting effects of linezolid on healthy and dysfunctional human neutrophils: reducing C5a-induced injury2020
Dr Will Jones
Stephen Rice
Dr Michael Power
Dr Gregory Maniatopoulos
Dr Jana Suklan
et al.
Cost consequences for the NHS of using a two-step testing method for the detection of Clostridium difficile with a point of care, polymerase chain reaction test as the first step2020
Dr Tom Hellyer
Professor John Simpson
Could host response guide VAP treatment? No answer yet – Authors' reply2020
Dr Elspeth Hulse
Professor John Simpson
Development of a histopathology scoring system for the pulmonary complications of organophosphorus insecticide poisoning in a pig model2020
Dr Joy Allen
Dr Andrea Gonzalez-Ciscar
Dr Clare Lendrem
Dr Jana Suklan
Dr Louise Johnston
et al.
Diagnostic and economic evaluation of a point-of-care test for respiratory syncytial virus2020
Dr Laura Jardine
Dr Urszula Cytlak-Chaudhuri
Dr Merry Gunawan
Dr Gary Reynolds
Dr Kile Green
et al.
Donor monocyte-derived macrophages promote human acute graft-versus-host disease2020
Dr Mary Neal
Dr Benjamin Pippard
Professor John Simpson
Professor Peter Thelwall
Dynamic susceptibility contrast 19F-MRI of inhaled perfluoropropane: a novel approach to combined pulmonary ventilation and perfusion imaging2020
Dr Sara Graziadio
Amanda Winter
Dr Clare Lendrem
Dr Jana Suklan
Dr Will Jones
et al.
How to Ease the Pain of Taking a Diagnostic Point of Care Test to the Market: A Framework for Evidence Development.2020
Daniel Brooks
Dr Sarah Wiscombe
Professor John Simpson
Dr Anthony Rostron
Human lipopolysaccharide models provide mechanistic and therapeutic insights into systemic and pulmonary inflammation2020
Dr Tom Hellyer
Professor John Simpson
Pulmonary Aspergillosis in Patients with Suspected Ventilator-associated Pneumonia in UK ICUs2020
Dr Aaron Ions Gardner
Dr Iram Haq
Professor John Simpson
Dr Vinciane Saint-Criq
Dr Bernard Verdon
et al.
Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis2020
Dr Jim Macfarlane
Dr Marie-Helene Ruchaud
Jonathan Scott
Professor John Simpson
Src kinase inhibition with dasatinib impairs neutrophil function and clearance of Escherichia coli infection in a murine model of acute lung injury2020
Dr Kathryn Musgrave
Jonathan Scott
Dr Wezi Sendama
Dr Patrick Kesteven
Dr Marie-Helene Ruchaud
et al.
The differential surface expression of tissue factor between monocyte subsets2020
Eoin Moloney
Dr Joy Allen
Dr Peter Carey
Dr Louise Johnston
Rachel O'Leary
et al.
Efficiency and Health Economic Evaluations of BD OneFlow™ Flow Cytometry Reagents for Diagnosing Chronic Lymphoid Leukemia2019
Jason Powell
Dr Bernard Verdon
Emerita Professor Janet Wilson
Professor John Simpson
Professor Jeffrey Pearson
et al.
Establishment of an immortalized human subglottic epithelial cell line2019
Dr Laura Jardine
Dr Sarah Wiscombe
Dr Gary Reynolds
Dr David McDonald
Andrew Fuller
et al.
Lipopolysaccharide inhalation recruits monocytes and dendritic cell subsets to the alveolar airspace.2019
Dr Mary Neal
Dr Benjamin Pippard
Dr Kieren Hollingsworth
Dr Prosenjit Dutta
Professor John Simpson
et al.
Optimized and accelerated 19F-MRI of inhaled perfluoropropane to assess regional pulmonary ventilation2019
Dr Mary Neal
Dr Benjamin Pippard
Professor John Simpson
Professor Peter Thelwall
Optimized and accelerated 19F‐MRI of inhaled perfluoropropane to assess regional pulmonary ventilation2019
Dr Prosenjit Dutta
Dr Wendy Funston
Helen Mossop
Vicky Ryan
Rhys Jones
et al.
Randomised, double-blind, placebo-controlled pilot trial of omeprazole in idiopathic pulmonary fibrosis2019
Dr Venetia Bigley
Dr Urszula Cytlak-Chaudhuri
Dr Laura Jardine
Dr Kile Green
Dr Merry Gunawan
et al.
Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation2018
Dr Sara Graziadio
Rachel O'Leary
Dr Deborah Stocken
Dr Joy Allen
Professor John Simpson
et al.
Can mid-regional pro-adrenomedullin (MR-proADM) increase the prognostic accuracy of NEWS in predicting deterioration in patients admitted to hospital with mild to moderately severe illness? A prospective single-centre observational study2018
Dr Gill Hulme
Ian Dimmick
Dr Andrea Rossi
Professor John Simpson
Cell-surface signatures of immune dysfunction risk-stratify critically ill patients: INFECT study2018
Dr Louise Johnston
Dr Michael Power
Professor Philip Sloan
Anna Long
Dr Angela Silmon
et al.
Clinical performance evaluation of the Idylla NRAS-BRAF mutation test on retrospectively collected formalin-fixed paraffin-embedded colorectal cancer tissue2018
Dr Joy Allen
Rachel O'Leary
Dr Sara Graziadio
Dr William Jones
Professor John Simpson
et al.
Cost implications for the NHS of using the Alere™ i Influenza A & B near patient test with nasal swabs2018
Dr Joy Allen
Rebecca O'Leary
Dr Michael Power
Professor John Simpson
Professor Luke Vale
et al.
Diagnostic accuracy and cost analysis of the Alere™ i Influenza A&B near-patient test using throat swabs2018
Dr John Wright
Dr Gill Hulme
Professor John Simpson
Early PREdiction of Sepsis using leukocyte surfacebiomarkers: The ExPRES-Sepsis cohort study2018
Jason Powell
Dr James Garnett
Dr Michael Mather
Dr Faye Cooles
Dr Bernard Verdon
et al.
Excess Mucin Impairs Subglottic Epithelial Host Defense in Mechanically Ventilated Patients2018
Dr John Widdrington
Dr Aurora Gomez Duran
Dr Angela Pyle
Dr Marie-Helene Ruchaud
Jonathan Scott
et al.
Exposure of Monocytic Cells to Lipopolysaccharide Induces Coordinated Endotoxin Tolerance, Mitochondrial Biogenesis, Mitophagy, and Antioxidant Defenses2018
Dr Carlos Echevarria
Dr Tom Hartley
Dr John Steer
Professor John Simpson
Emeritus Professor John Gibson
et al.
Home treatment of COPD exacerbation selected by DECAF score: a non-inferiority, randomised controlled trial and economic evaluation2018
Dr Sara Graziadio
Professor John Simpson
Dr Joy Allen
Interactive visualisation for interpreting diagnostic test accuracy study results2018
Dr Vicky Ewan
Dr William Reid
Dr Mark Shirley
Professor John Simpson
Professor Stephen Rushton
et al.
Oropharyngeal microbiota in frail older patients unaffected by time in hospital2018
Dr Emma Pinder
Dr Anthony Rostron
Dr Tom Hellyer
Dr Marie-Helene Ruchaud
Jonathan Scott
et al.
Randomised controlled trial of GM-CSF in critically ill patients with impaired neutrophil phagocytosis2018
Professor John Simpson
Dr Jeffry Hogg
Michael Clarke
The Red Eye and Systemic Infection2018
Dr Tom Hellyer
Professor John Simpson
16S pan-bacterial PCR can accurately identify patients with ventilator-associated pneumonia2017
Dr Benjamin Pippard
Dr Mary Neal
Dr Prosenjit Dutta
Professor John Simpson
Professor Peter Thelwall
et al.
19F-MRI of inhaled perfluoropropane gas: a novel approach to ventilation imaging2017
Jonathan Scott
Professor John Simpson
Aspirin reduces lipopolysaccharide-induced pulmonary inflammation in human models of ARDS2017
Dr Mary Neal
Dr Prosenjit Dutta
Professor John Simpson
Professor Andrew Blamire
Professor Peter Thelwall
et al.
Determination of RF and acquisition properties for optimal scan performance in 19F-MRI of inhaled perfluoropropane2017
Dr Vicky Ewan
Professor John Simpson
Hospital-acquired pneumonia surveillance - an unmet need2017
Dr Mary Neal
Dr Benjamin Pippard
Dr Kieren Hollingsworth
Professor John Simpson
Professor Andrew Blamire
et al.
Maximising Performance of 19F MRI of Inhaled Perfluoropropane2017
Dr John Widdrington
Dr Aurora Gomez Duran
Dr Jannetta Steyn
Dr Angela Pyle
Dr Marie-Helene Ruchaud
et al.
Mitochondrial DNA depletion induces innate immune dysfunction rescued by IFN-γ2017
Professor Anthony De Soyza
Jonathan Scott
Professor John Simpson
The heterogeneity of systemic inflammation in bronchiectasis2017
Dr Carlos Echevarria
Professor John Simpson
Emeritus Professor John Gibson
Professor Stephen Bourke
The PEARL score predicts 90-day readmission or death after hospitalisation for acute exacerbation of COPD2017
Professor John Simpson
Dr Gill Hulme
Dr Sharon Cookson
Ian Dimmick
Early PREdiction of Severe Sepsis (ExPRES-Sepsis) study: protocol for an observational derivation study to discover potential leucocyte cell surface biomarkers2016
Dr Tom Hellyer
Jennie Parker
Professor John Simpson
Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic Use (VAPrapid-2): study protocol for a randomised controlled trial2016
Jonathan Scott
Dr Jim Macfarlane
Dr Tom Hellyer
Dr Anthony Rostron
Dr Marie-Helene Ruchaud
et al.
Exchange protein directly activated by cyclic AMP (EPAC) activation reverses neutrophil dysfunction induced by beta(2)-agonists, corticosteroids, and critical illness2016
Dr Carlos Echevarria
Dr Colin Muirhead
Dr John Steer
Professor John Simpson
Dr Grant Gibson
et al.
Hot decaf: a rct comparing home treatment and inpatient care in copd exacerbations selected by low risk decaf score2016
Dr Kate Musgrave
Professor John Simpson
Dr Patrick Kesteven
Is there any clinical or biological difference that distinguishes recurrence from non-recurrence after idiopathic PE?2016
Dr Tom Hellyer
Professor John Simpson
Low-pathogenicity Mycoplasma spp. alter human monocyte and macrophage function and are highly prevalent among patients with ventilator-acquired pneumonia2016
Lorelle Dismore
Dr Carlos Echevarria
Professor John Simpson
Dr Grant Gibson
Professor Stephen Bourke
et al.
Positive drivers and potential barriers to implementation of hospital at home selected by low risk decaf score2016
Professor John Simpson
Dr Gill Hulme
Ian Dimmick
Predictive value of cell-surface markers in infections in critically ill patients: protocol for an observational study (ImmuNe FailurE in Critical Therapy (INFECT) Study)2016
Dr Emma Pinder
Dr Anthony Rostron
Thomas Hellyer
Dr Marie-Helene Ruchaud
Jonathan Scott
et al.
Randomised Controlled Trial Of Granulocyte Macrophage Colony Stimulating Factor In Critically Ill Patients With Impaired Neutrophil Function2016
Dr Tom Hellyer
Dr Vicky Ewan
Peter Wilson
Professor John Simpson
The Intensive Care Society recommended bundle of interventions for the prevention of ventilator-associated pneumonia2016
Professor John Simpson
Toll- Like Receptor 3 (TLR3) L412F Single Nucleotide Polymorphism as a Causative Factor in Disease Progression in Idiopathic Pulmonary Fibrosis (IPF) During Bacterial Infection in TLR3-defective patients2016
Dr Kate Musgrave
Professor John Simpson
Use of age adjusted d-dimer monitoring to assist the withdrawal of anticoagulation following unprovoked pulmonary embolism2016
Dr Carlos Echevarria
Dr John Steer
Dr Chris Stenton
Dr Ian Steen
Professor John Simpson
et al.
Validation of the DECAF score to predict hospital mortality in acute exacerbations of COPD2016
Dr Alice Wort
Professor John Simpson
Dr David Spencer
Dr Matthew Thomas
Dr Malcolm Brodlie
et al.
Viruses associated with community-acquired pneumonia in children – a large prospective study in the post-prevenar 13 era2016
Dr Tom Hellyer
Dr Simon Baudouin
Dr Stephen Wright
Melinda Jeffels
Dr Marie-Helene Ruchaud
et al.
Diagnostic accuracy of pulmonary host inflammatory mediators in the exclusion of ventilator-acquired pneumonia2015
Professor John Simpson
Sleep-disordered breathing and idiopathic pulmonary fibrosis - is there an association?2015
Anna Irvin
Kasim Jiwa
Dr Sonya Carnell
Professor John Simpson
Professor Anthony De Soyza
et al.
Sputum Neutrophils but not Interleukin-8 (IL-8) or Interleukin 17 (IL-17) Correlate with the Bronchiectasis Severity Index (BSI)2015
Dr Carlos Echevarria
Dr John Steer
Dr Chris Stenton
Dr Ian Steen
Professor John Simpson
et al.
The PEARL score predicts 90 day readmission or death following hospitalisation for an exacerbation of COPD2015
Dr Jim Macfarlane
Jonathan Scott
Dr Marie-Helene Ruchaud
Dr Anjam Khan
Professor John Simpson
et al.
Src/bcr-abl Inhibition with Dasatinib in Sterile and Non-Sterile Acute Lung Inflammation2014
Dr Emma Browne
Dr Tom Hellyer
Dr Simon Baudouin
Professor John Simpson
A national survey of the diagnosis and management of suspected ventilator-associated pneumonia2014
Professor John Simpson
Cathelicidin Host Defence Peptide Augments Clearance of Pulmonary Pseudomonas aeruginosa Infection by Its Influence on Neutrophil Function In Vivo2014
Rhys Jones
Amaran Krishnan
Professor Jeffrey Pearson
Professor John Simpson
Professor Michael Griffin
et al.
Characterisation of Reflux and Aspiration in Idiopathic Pulmonary Fibrosis; An Integrated Approach2014
Professor John Simpson
Differential response to bacteria, and tollip expression, in the human respiratory tract2014
Professor John Simpson
Functional characterisation of human pulmonary monocyte-like cells in lipopolysaccharide-mediated acute lung inflammation2014
Professor John Simpson
Innate immune responses after resection for lung cancer via video-assisted thoracoscopic surgery and thoracotomy2014
Professor John Simpson
Leukoreduced blood transfusion does not increase circulating soluble markers of inflammation: a randomized controlled trial2014
Dr Marie-Helene Ruchaud
Jonathan Scott
Professor John Simpson
MPLA inhibits release of cytotoxic mediators from human neutrophils while preserving efficient bacterial killing2014
Professor John Simpson
Reply: The Alveolar Macrophage and Acute Respiratory Distress Syndrome: A Silent Actor?2014
Professor John Simpson
Respiratory Complications of Organophosphorus Nerve Agent and Insecticide Poisoning Implications for Respiratory and Critical Care2014
Professor John Simpson
Serial characterisation of monocyte and neutrophil function after lung resection2014
Professor John Simpson
Thrombolysis for acute submassive pulmonary embolism: CON viewpoint2014
Professor John Simpson
A Randomized Controlled Trial of Peripheral Blood Mononuclear Cell Depletion in Experimental Human Lung Inflammation2013
Dr Tom Hellyer
Professor John Simpson
Antibiotic Prophylaxis for Ventilator-Associated Pneumonia More Is Less or Less Is More?2013
Dr Catherine Popplewell
Dr Marie-Helene Ruchaud
Jonathan Scott
Emeritus Professor Nick Europe-Finner
Professor John Simpson
et al.
Carboplatin and Gemcitabine Impair Neutrophil Phagocytic Function2013
Professor John Simpson
Combined dysfunctions of immune cells predict nosocomial infection in critically ill patients2013
Professor John Simpson
Comment on "Changes and Regulation of the C5a Receptor on Neutrophils during Septic Shock in Humans"2013
Dr Marie-Helene Ruchaud
Dr Katy Hester
Dr Jim Macfarlane
Emeritus Professor Nick Europe-Finner
Professor John Simpson
et al.
Effect of granulocyte-macrophage colony-stimulating factor on neutrophil function in idiopathic bronchiectasis2013
Professor John Simpson
Proteolytic cleavage of elafin by 20S proteasome may contribute to inflammation in acute lung injury2013
Dr Jim Macfarlane
Dr Marie-Helene Ruchaud
Jonathan Scott
Dr David Bulmer
Dr Anjam Khan
et al.
Src Kinase Inhibition Attenuates Neutrophil Degranulation Without Impairing Bacterial Killing: A Possible Therapeutic Strategy for Acute Lung Injury?2013
Dr Tamir Ali
Dr Sylvia Worthy
Professor John Simpson
Statin use and cigarette smoking are associated with lower incidence of radiation pneumonitis2013
Professor John Simpson
The Toll-like Receptor 3 L412F Polymorphism and Disease Progression in Idiopathic Pulmonary Fibrosis2013
Professor John Simpson
Ventilator associated pneumonia: can we ensure that a quality indicator does not become a game of chance?2013
Professor John Simpson
A novel subpopulation of monocyte-like cells in the human lung after LPS inhalation2012
Professor John Simpson
Bronchoalveolar Lavage does not affect the Acute Inflammatory Response Following Bronchoscopy and Mediastinoscopy2012
Professor John Simpson
In Vivo Mononuclear Cell Tracking Using Superparamagnetic Particles of Iron Oxide Feasibility and Safety in Humans2012
Professor John Simpson
Monocytes control second-phase neutrophil emigration in established lipopolysaccharide-induced murine lung injury2012
Professor John Simpson
Proteolytic Cleavage of Elafin by 20S Proteasome May Contribute to Inflammation in Acute Lung Injury2012
Professor John Simpson
Pulmonary and systemic effects of mononuclear leukapheresis2012
Professor John Simpson
Regulation of Transforming Growth Factor-beta 1-driven Lung Fibrosis by Galectin-32012
Professor John Simpson
Ventilator-Associated Pneumonia Is Characterized by Excessive Release of Neutrophil Proteases in the Lung2012
Professor John Simpson
A randomised controlled trial of nebulised gentamicin in non-cystic fibrosis bronchiectasis2011
Professor John Simpson
Acute Lung Injury2011
Professor John Simpson
C5a-mediated neutrophil dysfunction is RhoA-dependent and predicts infection in critically ill patients2011
Professor John Simpson
Hospital-acquired infection: from doctors to patients, with complements2011
Professor John Simpson
Ly6C(hi) Monocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis2011
Professor John Simpson
Multi-modal molecular imaging approaches to detect primary cells in preclinical models2011
Dr Rebecca Hammersley
Professor John Simpson
S137 The natural history of IPF in patients eligible for clinical trials vs patients not eligible2011
Professor John Simpson
The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system2011
Professor John Simpson
WAP domain proteins as modulators of mucosal immunity2011
Professor John Simpson
Association of Fcy RIIa R131H polymorphism with idiopathic pulmonary fibrosis severity and progression2010
Professor John Simpson
Diagnostic importance of pulmonary interleukin-1 beta and interleukin-8 in ventilator-associated pneumonia.2010
Professor John Simpson
Fcy receptor IIIb (CD16b) polymorphisms are associated with susceptibility to idiopathic pulmonary fibrosis2010
Professor John Simpson
NO-loaded Zn2+-exchanged zeolite materials: a potential bi-functional anti-bacterial strategy2010
Professor John Simpson
Panton-Valentine leukocidin (PVL) pneumonia: case report2010
Professor John Simpson
Prognostic significance of the lung scintigraphy scan result and corresponding chest x-ray in patients with suspected pulmonary embolism2010
Professor John Simpson
The human cathelicidin LL-37 preferentially promotes apoptosis of infected airway epithelium2010
Emeritus Professor John Harris
Professor John Simpson
The Major Solvent in Agricultural Dimethoate Preparations is Essential for Toxicity in Minipigs [abstract]2010
Professor John Simpson
C5a mediates peripheral blood neutrophil dysfunction in critically ill patients2009
Professor John Simpson
Clinically suspected acute pulmonary embolism: a comparison of presentation, radiological features and outcome in patients with and without PE2009
Professor John Simpson
Evaluation of the effect of diagnostic methodology on the reported incidence of ventilator-associated pneumonia2009
Professor John Simpson
Idiopathic venous thromboembolic disease is associated with a poorer prognosis from subsequent malignancy2009
Professor John Simpson
Recent human-to-poultry host jump, adaptation, and pandemic spread of Staphylococcus aureus.2009
Professor John Simpson
Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not pro-inflammatory to phagocytosing macrophages2009
Professor John Simpson
The influence of meteorological variables on the development of deep vein thrombosis2009
Professor John Simpson
Trappin-2 promotes early clearance of pseudomonas aeruginosa through CD14-dependent macrophage activiation and neutrophil recruitment2009
Professor John Simpson
A 29 year old man with chest pain and haemoptysis2008
Professor John Simpson
Dunking doughnuts into cells - selective cellular translocation and in vivo analysis of polymeric micro-doughnuts2008
Professor John Simpson
Galectin-3 reduces the severity of pneumococcal pneumonia by augmenting neutrophil function2008
Professor John Simpson
Reactive oxygen species regulate neutrophil recruitment and survival in pneumococcal pneumonia2008
Professor John Simpson
A profile of lower limb deep venous thrombosis: the hidden menace of below knee DVT2007
Professor John Simpson
Inflammation-associated remodelling and fibrosis in the lung - a process and an end point2007
Professor John Simpson
Endogenous pulmonary antibiotics2006
Professor John Simpson
Towards gene therapy for inflammatory and infective pulmonary diseases2004
Professor John Simpson
Adenoviral augmentation of elafin protects the lung against acute injury mediated by activated neutrophils and bacterial infection2001
Professor John Simpson
Expression of plasminogen activators and plasminogen activator inhibitors in squamous cell carcinoma of the lung is subject to marked regional variation2001
Professor John Simpson
Regulation of adenovirus-mediated elafin transgene expression by bacterial lipopolysaccharide2001
Professor John Simpson
Current and future applications of gene therapy in respiratory disease2000
Professor John Simpson
Emergency pre-hospital management of patients admitted with acute asthma2000
Professor John Simpson
Pet ownership and asthma morbidity2000
Professor John Simpson
Circulating tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor type 1 (PAI-1) in proliferative diabetic retinopathy: a pilot study1999
Professor John Simpson
Elafin (elastase-specific inhibitor) has antimicrobial activity against Gram positive and Gram negative respiratory pathogens1999
Professor John Simpson
Adenovirus-mediated expression of an elastase-specific inhibitor (elafin): a comparison of different promoters1998
Professor John Simpson
Do UK patients with complications of diabetes mellitus receive the financial State benefits to which they are entitled?1998
Professor John Simpson
Does chronic smoking influence fibrinolytic potential in Type 1 diabetes mellitus?1998
Professor John Simpson
Starting home nebulizer therapy: patients' expectations and subsequent outcome at two months1998
Professor John Simpson
The management of pulmonary tuberculosis in adults notified in Scotland in 19931998
Professor John Simpson
The effects of smoking on the fibrinolytic potential of plasma and platelets1997
Dr Petros Perros
Professor John Simpson
Non-islet cell tumour-associated hypoglycaemia: 111In-octreotide imaging and efficacy of octreotide, growth hormone and glucocorticosteroids1996
Professor John Simpson
Distribution of plasminogen activator inhibitor (PAI-1) in tissues1991
Professor John Simpson
The platelet and plasma pools of plasminogen activator inhibitor (PAI-1) vary independently in disease1990
Professor John Simpson
Plasminogen activator inhibitor (PAI-1) in plasma and platelets1988