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CNEUPRO: Novel biomarkers for neurodegenerative diseases

Lookup NU author(s): Dr Christopher Morris


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clinical NEUroPROteomics of neurodegenerative diseases (cNEUPRO) is a Specific Targeted Research Project (STREP) within the sixth framework program of the European Commission dedicated to the search for novel biomarker candidates for Alzheimer's disease and other neurodegenerative diseases. The ultimate goal of cNEUPRO is to identify one or more valid biomarker(s) in blood and CSF applicable to support the early and differential diagnosis of dementia disorders. The consortium covers all steps required for the discovery of novel biomarker candidates such as acquisition of high quality CSF and blood samples from relevant patient groups and controls, analysis of body fluids by various methods, and finally assay development and assay validation. Here we report the standardized procedures for diagnosis and preanalytical sample-handling within the project, as well as the status of the ongoing research activities and some first results. © 2010 Philipp Spitzer et al.

Publication metadata

Author(s): Spitzer P, Klafki H, Blennow K, Buée L, Esselmann H, Herruka S, Jimenez C, Klivenyi P, Lewczuk P, Maler J, Markus K, Meyer H, Morris C, Müller T, Otto M, Parnetti L, Soininen H, Schraen S, Teunissen C, Vecsei L, Zetterberg H, Wiltfang J

Publication type: Review

Publication status: Published

Journal: International Journal of Alzheimer's Disease

Year: 2010

Print publication date: 01/01/2010

ISSN (electronic): 2090-0252


DOI: 10.4061/2010/548145