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Platelets as potential link between diabetes and Alzheimer's disease

Lookup NU author(s): Professor Konstantinos StellosORCiD

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Abstract

© 2014 Bentham Science Publishers. Diabetes is a well-known risk factor for Alzheimer`s disease (AD) development in the elderly. The molecular link between diabetes and AD is still not completely understood. Recent evidence suggests that platelet activation observed in diabetes may contribute to AD development. The present review summarizes the common molecular mechanisms involved in the pathophysiology of diabetes and AD and suggests novel therapeutic targets for prevention of the onset or slowing the progression of this disease.

Publication metadata

Author(s): Randriamboavonjy V, Sopova K, Stellos K, Laske C

Publication type: Article

Publication status: Published

Journal: Current Alzheimer Research

Year: 2014

Volume: 11

Issue: 9

Pages: 862-868

Print publication date: 01/11/2014

Online publication date: 13/10/2014

Acceptance date: 01/03/2014

ISSN (print): 1567-2050

ISSN (electronic): 1875-5828

Publisher: Bentham Science Publishers B.V.

URL: https://doi.org/10.2174/156720501109141013115258

DOI: 10.2174/156720501109141013115258

PubMed id: 25430938

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