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Temporal changes in gastrointestinal fungi and the risk of autoimmunity during early childhood: the TEDDY study

Lookup NU author(s): Professor Christopher StewartORCiD

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Author(s): Auchtung TA, Stewart CJ, Smith DP, Triplett EW, Agardh D, Hagopian WA, Ziegler AG, Rewers MJ, She JX, Toppari J, Lernmark A, Akolkar B, Krischer JP, Vehik K, Auchtung JM, Ajami NJ, Petrosino JF

Publication type: Article

Publication status: Published

Journal: Nature Communications

Year: 2022

Volume: 13

Online publication date: 07/06/2022

Acceptance date: 09/05/2022

Date deposited: 23/03/2026

ISSN (electronic): 2041-1723

Publisher: Springer Nature

URL: https://doi.org/10.1038/s41467-022-30686-w

DOI: 10.1038/s41467-022-30686-w

Data Access Statement: TEDDY microbiome ITS2, 16S rRNA gene, and metagenomic sequencing data have been deposited in the NCBI database of Genotypes and Phenotypes (dbGaP) with the primary accession code phs001442.v3.p2. Clinical metadata analyzed during the current study is available through the NIDDK Central Repository [https://repository.niddk.nih.gov/studies/teddy]. The data are available under controlled access in accordance with dbGaP and NIDDK authorization. Access can be obtained by requests at the listed websites. HMP “Healthy Human Subjects” HiSeq metagenomic data is available at the HMP Data Analysis and Coordinating Center website [https://portal.hmpdacc.org]. Metagenomic data from other studies (listed in Supplementary Table 1) is available via the NCBI SRA Run Selector [https://www.ncbi.nlm.nih.gov/Traces/study]. HMP ITS2 sequences are available at NCBI under BioProject PRJNA356769. The database used for HumanMycobiomeScan (“Fungi_Fuller”) containing 288 genomes is available in Supplementary Data

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