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Browsing publications by Dr Amir Enshaei.

Newcastle AuthorsTitleYearFull text
Dr Carmela Ciardullo
Dr Katarzyna Szoltysek
Dr Peixun Zhou
Dr Elaine Willmore
Dr Amir Enshaei
et al.
Low BACH2 expression predicts adverse outcome in chronic lymphocytic leukaemia2022
Professor Anthony Moorman
Emilio Barretta
Ellie Butler
Eleanor Ward
Dr Amir Enshaei
et al.
Prognostic impact of chromosomal abnormalities and copy number alterations in adult B-cell precursor acute lymphoblastic leukaemia: a UKALL14 study2022
Dr Amir Enshaei
Professor Anthony Moorman
Defining low-risk high hyperdiploidy in patients with paediatric acute lymphoblastic leukaemia: a retrospective analysis of data from the UKALL97/99 and UKALL2003 clinical trials2021
Dr Amir Enshaei
Finding the Ground-Truth from Multiple Labellers: Why Parameters of the Task Matter2021
Dr Amir Enshaei
Fully-Automatic Pipeline for Document Signature Analysis to Detect Money Laundering Activities2021
Claire Schwab
Daniel Murdy
Ellie Butler
Dr Amir Enshaei
Emily Winterman
et al.
Genetic characterisation of childhood B-other-acute lymphoblastic leukaemia in UK patients by fluorescence in situ hybridisation and Multiplex Ligation-dependent Probe Amplification2021
Dr Alex Newman
Dr Masood Zaka
Dr Peixun Zhou
Alex Blain
Dr Amy Erhorn
et al.
Genomic abnormalities of TP53 define distinct risk groups of paediatric B-cell non-Hodgkin lymphoma2021
Dr Amir Enshaei
Minimal residual disease, long-term outcome, and IKZF1 deletions in children and adolescents with Down syndrome and acute lymphocytic leukaemia: a matched cohort study2021
Dr Amir Enshaei
Professor Anthony Moorman
Minimal Residual Disease, Long-Term Outcome, and IKZF1 Deletions in Down Syndrome Acute Lymphoblastic Leukemia in a Matched Cohort Study2021
Yuzhe Shi
Melanie Beckett
Dr Helen Blair
Dr Ricky Tirtakusuma
Dr Sirintra Nakjang
et al.
Phase II-like murine trial identifies synergy between dexamethasone and dasatinib in T-cell acute lymphoblastic leukemia2021
Professor Anthony Moorman
Emilio Barretta
Ellie Butler
Eleanor Ward
Dr Amir Enshaei
et al.
Prognostic impact of chromosomal abnormalities and copy number alterations in adult B-cell precursor acute lymphoblastic leukaemia: a UKALL14 study2021
Dr Tom Creasey
Dr Amir Enshaei
Claire Schwab
Kathryn Watts
Gavin Cuthbert
et al.
Single nucleotide polymorphism (SNP) array-based signature of low hypodiploidy in acute lymphoblastic leukemia2021
Dr Amir Enshaei
Dr Sirintra Nakjang
Lynne Minto
Professor Julie Irving
Beth Poole
et al.
The genomic landscape of teenage and young adult T-cell acute lymphoblastic leukemia2021
Dr Amir Enshaei
Professor Christine Harrison FRCPath FMedSci
Claire Schwab
Professor Anthony Moorman
A validated novel continuous prognostic index to deliver stratified medicine in pediatric acute lymphoblastic leukemia2020
Dr Matthew Bashton
Robin Hollis
Dr Sarra Ryan
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
et al.
Concordance of copy number abnormality detection using SNP arrays and Multiplex Ligation-dependent Probe Amplification (MLPA) in acute lymphoblastic leukaemia2020
Dr Matthew Bashton
Dr Amir Enshaei
Molecular Characterisation of Participants in the Phazar Trial Reveals Prognostic Impact of Mutations in Advanced-Phase-MPN2020
Professor Anthony Moorman
Dr Amir Enshaei
Dr Tobias Menne
Clinical Efficacy of a Novel Validated Prognostic Index for Trial Design in Adult Acute Lymphoblastic Leukaemia2019
Dr Amir Enshaei
Professor Anthony Moorman
Combining Genotype Profiling with MRD for More Accurate Prognostication in Acute Lymphoblastic Leukemia2019
Professor Anthony Moorman
Dr Amir Enshaei
Minimal Residual Disease and IKZF1 As Predictors of Relapse, and Increased Treatment Related Mortality in Down Syndrome Acute Lymphoblastic Leukemia: A Unique and Large International Matched Case-Control Study2019
Dr Tom Creasey
Dr Amir Enshaei
Kathryn Watts
Gavin Cuthbert
Claire Schwab
et al.
Single Nucleotide Polymorphism Array-Based Signature of Genetic Ploidy Groups in Acute Lymphoblastic Leukemia2019
Dr Lina Hamadeh
Dr Amir Enshaei
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
et al.
Validation of the United Kingdom copy-number alteration classifier in 3239 children with B-cell precursor ALL2019
Dr Peixun Zhou
Dr Amir Enshaei
Alex Newman
Dr Amy Erhorn
Amy Barnard
et al.
A genomic classification model enables risk stratification of paediatric endemic Burkitt lymphoma2018
Dr Peixun Zhou
Dr Amir Enshaei
Alex Newman
Dr Amy Erhorn
Amy Barnard
et al.
A Genomic Classification Model Enables Risk Stratification of Paediatric Endemic Burkitt Lymphona in Malawi2018
Alex Newman
Dr Masood Zaka
Dr Peixun Zhou
Dr Amy Erhorn
Dr Rachel Crossland
et al.
Biallelic inactivation of TP53 is associated with an increased risk of relapse in paediatric B-cell non-Hodgkin lymphoma (B-NHL)2018
Dr Amir Enshaei
Professor Christine Harrison FRCPath FMedSci
Dr Sujith Samarasinghe
Claire Schwab
Professor Anthony Moorman
et al.
Genotype-Specific Minimal Residual Disease Interpretation Improves Stratification in Pediatric Acute Lymphoblastic Leukemia2017
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Reza Rafiee
Dr Matthew Bashton
Dr Amir Enshaei
et al.
Minimal methylation classifier (MIMIC): A novel method for derivation and rapid diagnostic detection of disease-associated DNA methylation signatures2017
Dr Carmela Ciardullo
Dr Elaine Willmore
Dr Amir Enshaei
Dr Peixun Zhou
Dr Vikki Rand
et al.
BACH2 and BCL6 Cooperatively Fuction as Tumour Suppressors in CLL2016
Dr Lisa Russell
Lisa Jones
Dr Amir Enshaei
Dr Stefano Tonin
Sarra Ryan
et al.
Characterisation of the genomic landscape of CRLF2-rearranged acute lymphoblastic leukemia2016
Professor Anthony Moorman
Dr Amir Enshaei
Dr Sujith Samarasinghe
Integrating Genetic Risk Factors with Age, Presenting White Cell Count and MRD Response As Continuous Variables to Predict Relapse in Paediatric Acute Lymphoblastic Leukemia (ALL)2016
Professor Julie Irving
Dr Amir Enshaei
Dr Amy Erhorn
Lynne Minto
Claire Schwab
et al.
Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukaemia2016
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Reza Rafiee
Dr Matthew Bashton
Dr Amir Enshaei
et al.
Routine Diagnostic Medulloblastoma Subgrouping Using Low-Cost, Low-Input DNA Methylomics: Application to Trials Cohorts Previously Refractory-to-Analysis2016
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Reza Rafiee
Dr Matthew Bashton
Dr Amir Enshaei
et al.
Routine molecular subgrouping of medulloblastoma: Bridging the divide between research and the clinic using low-cost, mass spectrometry-based DNA methylomics2016
Claire Schwab
Dr Amir Enshaei
Dr Lisa Russell
Professor Anthony Moorman
The Frequency and Outcome of Ph-like ALL Associated Abnormalities in Childhood Acute Lymphoblastic Leukaemia Treated on MRC UKALL20032016
Dr Paul Sinclair
Joanna Cheng
Prahlad Raninga
Rebecca Hanna
Shaun Hollern
et al.
A Targeted Functional Clone Tracking Assay for the Identification of Tumour Suppressor Genes in BCP- ALL Implicates the Transcription Factors FOXO3 and PRDM12015
Dr Al Gabriel
Dr Amir Enshaei
Jennifer Taylor
Dr Amy Erhorn
Claire Schwab
et al.
Age specific incidence of partner gene and secondary abnormalities in MLL positive acute lymphoblastic leukaemia (ALL)2015
Dr Amir Enshaei
Professor Craig Robson
Professor Richard Edmondson
Artificial Intelligence Systems as Prognostic and Predictive Tools in Ovarian Cancer2015
Dr Lisa Russell
Lisa Jones
Dr Amir Enshaei
Jamie Rutherford
Dr Stefano Tonin
et al.
Clincial and Genetic Landscapes Differ Between IGH-CRLF2 and P2RY8-CRLF2 Acute Lymphoblastic Leukaemia2015
Dr Lisa Russell
Lisa Jones
Dr Amir Enshaei
Dr Stefano Tonin
Dr Sarra Ryan
et al.
Clincial and Genetic Landscapes Differ Between IGH-CRLF2 and P2RY8-CRLF2 Acute Lymphoblastic Leukaemia2015
Professor Anthony Moorman
Professor Julie Irving
Dr Amir Enshaei
Dr Amy Erhorn
Lynne Minto
et al.
Composite Index for Risk Prediction in Relapsed Childhood Acute Lymphoblastic Leukaemia2015
Dr Al Gabriel
Fadhel Alsaid Naji
Dr Ed Schwalbe
Dr Sirintra Nakjang
Dr Simon Cockell
et al.
Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia2015
Dr Amir Enshaei
Feature Selection with Targeted Projection Pursuit2015
Dr Dino Masic
Dr Amir Enshaei
Lisa Jones
Professor Christine Harrison FRCPath FMedSci
Dr Lisa Russell
et al.
Genetic Characterisation of Immunoglobulin Heavy Chain Locus CCAAT Enhancer-Binding Protein Translocated Acute Lymphoblastic Leukaemia2015
Dino Mašić
Dr Amir Enshaei
Lisa Jones
Professor Christine Harrison FRCPath FMedSci
Dr Lisa Russell
et al.
Genetic Characterisation of Immunoglobulin Heavy Chain Locus CCAAT Enhancer-Binding Protein Translocated Acute Lymphoblastic Leukaemia2015
Dr Amir Enshaei
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Dr Sujith Samarasinghe
Integration of Minimal Residual Disease with Other Patient Risk Factors Identifies a Population with Very Poor Overall Survival in Pediatric ALL: Results from the UKALL 2003 Trial2015
Dr Amir Enshaei
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Dr Sujith Samarasinghe
Long Term Overall Survival of Greater Than 98% in Childhood ALL Patients with Good Risk Features and Low Risk MRD: Results from a Large Multi-Center Randomized Controlled Trial, UKALL 20032015
Dr Amir Enshaei
Professor Anthony Moorman
Professor Christine Harrison FRCPath FMedSci
Dr Sujith Samarasinghe
Long Term Overall Survival of Greater Than 98% in Childhood ALL Patients with Good Risk Features and Low Risk MRD:A Results from a Large Multi-Center Randomized Controlled Trial, UKALL 20032015
Claire Schwab
Dr Amir Enshaei
Professor Anthony Moorman
Prognostic value of rare IKZF1 deletion in childhood b-cell precursor acute lymphoblastic leukemia: an international collaborative study2015
Dr Amir Enshaei
Claire Schwab
Dr Lucy Chilton
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
et al.
Risk Factor Analysis in Paediatric Acute Lymphoblastic Leukaemia with High Hyperdiploidy2015
Dr Amir Enshaei
Claire Schwab
Dr Lucy Chilton
Professor Anthony Moorman
Risk Factor Analysis in Paediatric Acute Lymphoblastic Leukaemia with High Hyperdiploidy2015
Dr Lisa Russell
Dr Amir Enshaei
Lisa Jones
Dr Amy Erhorn
Dr Dino Masic
et al.
IGH@ Translocations Are Prevalent in Teenagers and Young Adults With Acute Lymphoblastic Leukemia and Are Associated With a Poor Outcome2014
Claire Schwab
Dr Amir Enshaei
Professor Anthony Moorman
368 Prognostic Value of Rare IKZF1 deletions in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia: An International Collaborative Study2014
Professor Anthony Moorman
Dr Amir Enshaei
Claire Schwab
Dr Lucy Chilton
Alannah Elliott
et al.
A novel integrated cytogenetic and genomic classification refines risk stratification in pediatric acute lymphoblastic leukemia2014
Fadhel Alsaid Naji
Dr Vikki Rand
Professor Anthony Moorman
Dr Ed Schwalbe
Dr Amir Enshaei
et al.
Investigation of methylation based biomarkers for prediction of relapse in good prognostic cytogenetic subgroups of childhood acute lymphoblastic leukaemia2014
Claire Schwab
Dr Amir Enshaei
Professor Anthony Moorman
Prognostic Value of Rare IKZF1 deletions in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia: An International Collaborative Study2014
Dr Ed Schwalbe
Dr Debbie Hicks
Dr Reza Rafiee
Dr Amir Enshaei
Sandeep Potluri
et al.
Routine molecular subgrouping of medulloblastoma: Bridging the divide between research and the clinic using low-cost DNA methylomics2014
Professor Anthony Moorman
Dr Amir Enshaei
Claire Schwab
Dr Lucy Chilton
Integration Of Cytogenetic and Copy Number Alteration (CNA) Data Into a Single Risk Profile For Paediatric Acute Lymphoblastic Leukaemia (ALL)2013
Dr Amir Enshaei
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
Professor Anthony Moorman
Long-term follow-up of ETV6-RUNX1 ALL reveals that NCI risk, rather than secondary genetic abnormalities, is the key risk factor2013
Professor Anthony Moorman
Dr Lucy Chilton
Dr Amir Enshaei
Professor Christine Harrison FRCPath FMedSci
The clinical characteristics, therapy and outcome of 85 adults with acute lymphoblastic leukemia and t(4;11)(q21;q23)/MLL-AFF1 prospectively treated on UKALLXII/ECOG29932013
Professor Anthony Moorman
Dr Lucy Chilton
Dr Amir Enshaei
Professor Christine Harrison FRCPath FMedSci
The clinical characteristics, therapy and outcome of 85 adults with acute lymphoblastic leukemia and t(4;11)(q21;q23)/MLL-AFF1 prospectively treated in the UKALLXII/ECOG2993 trial2013
Claire Schwab
Dr Lucy Chilton
Dr Amir Enshaei
Heather Morrison
Lisa Jones
et al.
Clinical Relevance of Genes Commonly Deleted in Childhood B-Cell Precursor ALL (BCP-ALL)2012
Professor Anthony Moorman
Dr Amir Enshaei
Dr Lucy Chilton
Claire Schwab
Professor Christine Harrison FRCPath FMedSci
et al.
Delineation of Risk Factors in Paediatric Acute Lymphoblastic Leukaemia with Favourable Cytogenetics2012
Dr Lisa Russell
Lisa Jones
Dr Amy Erhorn
Dr Amir Enshaei
Dino Mašić
et al.
Immunoglobulin Heavy Chain Locus (IGH@) Translocations in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL): Incidence and Risk Stratification2012