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Browsing publications by Dr Simon Tual-Chalot.

Newcastle AuthorsTitleYearFull text
Dr Kateryna Sopova
Dr Simon Tual-Chalot
Dr Nikolaos Vlachogiannis
Dr Georgios Georgiopoulos
Dr Luke Spray
et al.
Effector T cell chemokine IP-10 predicts cardiac recovery and clinical outcomes post-myocardial infarction2023
Dr Rachael Redgrave
Dr Esha Singh
Dr Simon Tual-Chalot
Dr Catherine Park
Dr Darroch Hall
et al.
Exogenous Transforming Growth Factor-β1 and Its Helminth-Derived Mimic Attenuate the Heart's Inflammatory Response to Ischemic Injury and Reduce Mature Scar Size2023
Laura Booth
Dr Rachael Redgrave
Dr Simon Tual-Chalot
Professor Ioakim Spyridopoulos
Dr Helen Phillips
et al.
Heart Disease and Ageing: The Roles of Senescence, Mitochondria, and Telomerase in Cardiovascular Disease2023
Dr Georgios Georgiopoulos
Dr Kateryna Sopova
Dr Luke Spray
Dr Jose Coelho Lima Junior
Dr Simon Tual-Chalot
et al.
Modification of the GRACE Risk Score for Risk Prediction in Patients with Acute Coronary Syndromes2023
Dr Simon Tual-Chalot
Professor Kimon Stamatelopoulos
Dr Aikaterini Gatsiou
Professor Konstantinos Stellos
RNA-binding proteins in vascular inflammation and atherosclerosis2023
Dr Rachael Redgrave
Dr Emily Dookun
Laura Booth
Dr Maria Camacho Encina
Dr Omowumi Folaranmi
et al.
Senescent cardiomyocytes contribute to cardiac dysfunction following myocardial infarction2023
Dr Aikaterini Gatsiou
Dr Simon Tual-Chalot
Dr Georgios Georgiopoulos
Professor Kimon Stamatelopoulos
Professor Ioakim Spyridopoulos
et al.
The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation2023
Dr Rachael Redgrave
Dr Maria Camacho Encina
Dr Simon Tual-Chalot
Dr Omowumi Folaranmi
Dr Carmen Martin-Ruiz
et al.
The senescence-associated secretory phenotype as a biomarker for age-related myocardial remodelling and cardiovascular disease2023
Dr Simon Tual-Chalot
Dr Nikolaos Vlachogiannis
Dr Kateryna Sopova
Dr Aikaterini Gatsiou
Dr Georgios Georgiopoulos
et al.
Beta-secretase-1 antisense RNA is associated with vascular ageing and atherosclerotic cardiovascular disease2022
Professor Kimon Stamatelopoulos
Dr Georgios Georgiopoulos
Dr Nikolaos Vlachogiannis
Dr Kateryna Sopova
Dr Simon Tual-Chalot
et al.
Cathepsin S Levels and Survival Among Patients With Non-ST-Segment Elevation Acute Coronary Syndromes2022
Dr Simon Tual-Chalot
Professor Konstantinos Stellos
Chrono-pharmacology-based antiplatelet therapy for acute myocardial infarction2022
Dr Nikolaos Vlachogiannis
Dr Ken Baker
Dr Georgios Georgiopoulos
Dr Ina Schim van der Loeff
Dr Aidan Hanrath
et al.
Clinical frailty, and not features of acute infection, is associated with late mortality in COVID-19: a retrospective cohort study2022
Dr Simon Tual-Chalot
Professor Konstantinos Stellos
Noncoding RNAs in age-related cardiovascular diseases2022
Dr Simon Tual-Chalot
Professor Konstantinos Stellos
Targeting the adipose tissue: heart crosstalk in pressure overload-induced heart failure2022
Dr Anna Walaszczyk
Dr Emily Dookun
Dr Rachael Redgrave
Dr Pawel Palmowski
Dr Simon Tual-Chalot
et al.
Therapeutic potential of navitoclax in age-related cardiovascular diseases2022
Dr Aikaterini Gatsiou
Dr Georgios Georgiopoulos
Dr Nikolaos Vlachogiannis
Dr Simon Tual-Chalot
Lefteris Zormpas
et al.
Additive contribution of microRNA-34a/b/c to human arterial ageing and atherosclerosis2021
Dr Nikolaos Vlachogiannis
Dr Simon Tual-Chalot
Lefteris Zormpas
Professor Kimon Stamatelopoulos
Dr Aikaterini Gatsiou
et al.
Adenosine-to-inosine RNA editing contributes to type I interferon responses in systemic sclerosis2021
Dr Simon Tual-Chalot
Dr Nikolaos Vlachogiannis
Professor Konstantinos Stellos
Professor Kimon Stamatelopoulos
Circulating Amyloid Beta 1-40 Is Associated with Increased Rate of Progression of Atherosclerosis in Menopause: A Prospective Cohort Study2021
Dr Simon Tual-Chalot
Professor Konstantinos Stellos
MicroRNA-based therapy of postmyocardial infarction heart failure2021
Dr Simon Tual-Chalot
Professor Konstantinos Stellos
Therapeutic potential of adenosine kinase inhibition in vascular disease2021
Emily Dookun
Dr Anna Walaszczyk
Dr Rachael Redgrave
Dr Pawel Palmowski
Dr Simon Tual-Chalot
et al.
Clearance of senescent cells during cardiac ischemia–reperfusion injury improves recovery2020
Dr Simon Tual-Chalot
Dr Rachael Redgrave
Dr Esha Singh
Dr Benjamin Davison
Dr Catherine Park
et al.
Loss of endothelial Endoglin promotes high-output heart failure through peripheral arteriovenous shunting driven by VEGF signalling2020
Professor Kimon Stamatelopoulos
Lefteris Zormpas
Dr Nikolaos Vlachogiannis
Dr Simon Tual-Chalot
Professor Konstantinos Stellos
et al.
The Alzheimer's Disease Amyloid-Beta Hypothesis in Cardiovascular Aging and Disease: JACC Focus Seminar2020
Dr Nikolaos Vlachogiannis
Dr Kateryna Sopova
Dr Simon Tual-Chalot
Dr Aikaterini Gatsiou
Professor Konstantinos Stellos
et al.
Cathepsin B expression is associated with arterial stiffening and atherosclerotic vascular disease2019
Dr Kate Bailey
Dr Guy MacGowan
Dr Simon Tual-Chalot
Lauren Charlotte Phillips Phillips
Professor Deborah Henderson
et al.
Disruption of embryonic ROCK signalling reproduces the sarcomeric phenotype of Hypertrophic Cardiomyopathy2019
Rhys Anderson
Anthony Lagnado
Damien Maggiorani
Dr Anna Walaszczyk
Emily Dookun
et al.
Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence2019
Emily Dookun
Dr Anna Walaszczyk
Dr Rachael Redgrave
Dr Simon Tual-Chalot
Oliver Yausep
et al.
Navitoclax eliminates senescence attenuating remodelling and improving outcome to cardiac ischemia-reperfusion injury2019
Dr Anna Walaszczyk
Emily Dookun
Dr Rachael Redgrave
Dr Simon Tual-Chalot
Professor Ioakim Spyridopoulos
et al.
Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction.2019
Dr Simon Tual-Chalot
Professor Konstantinos Stellos
RNA epigenetics and cardiovascular diseases2019
Oliver Yausep
Emily Dookun
Dr Anna Walaszczyk
Dr Rachael Redgrave
Dr Simon Tual-Chalot
et al.
The Effects of Senolytics on Murine Cardiac Function and Morphology Post-Ischemia Reperfusion Injury2019
Emily Dookun
Dr Anna Walaszczyk
Dr Rachael Redgrave
Dr Simon Tual-Chalot
Oliver Yausep
et al.
Accumulation of cardiomyocyte senescence following ischaemia-reperfusion injury (IRI); a potential therapeutic target?2018
Emily Dookun
Dr Anna Walaszczyk
Dr Rachael Redgrave
Dr Simon Tual-Chalot
Oliver Yausep
et al.
Cardiomyocyte Senescence accumulates following Myocardial Infarction and Ischaemia-Reperfusion Injury.2018
Dr Simon Tual-Chalot
Professor Helen Arthur
Decreased Expression of Vascular Endothelial Growth Factor Receptor 1 Contributes to the Pathogenesis of Hereditary Hemorrhagic Telangiectasia Type 22018
Dr Anna Walaszczyk
Emily Dookun
Dr Rachael Redgrave
Dr Simon Tual-Chalot
Rhys Anderson
et al.
Senescence as a therapeutic target for myocardial ageing2018
Eunate Gallardo Vara
Dr Simon Tual-Chalot
Professor Helen Arthur
Soluble endoglin regulates expression of angiogenesis-related proteins and induction of arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia2018
Dr Rachael Redgrave
Dr Simon Tual-Chalot
Dr Benjamin Davison
Dr Esha Singh
Dr Darroch Hall
et al.
Cardiosphere-Derived Cells Require Endoglin for Paracrine-Mediated Angiogenesis2017
Dr Simon Tual-Chalot
Dr Rachael Redgrave
Professor Helen Arthur
Loss of Endothelial Endoglin Leads to Heart Failure2016
Professor Bob Anderson
Dr Simon Tual-Chalot
Dr Rachael Redgrave
Rebecca Dodds
Dr Andrew Owens
et al.
The role of cardiomyocyte senescence and regeneration in Ageing2016
Dr Rachael Redgrave
Dr Simon Tual-Chalot
Dr Benjamin Davison
Liz Greally
Dr Mauro Santibanez Koref
et al.
Using MRI to predict future adverse cardiac remodelling in a male mouse model of myocardial infarction2016
Dr Simon Tual-Chalot
Dr Benjamin Davison
Dr Rachael Redgrave
Professor Helen Arthur
Endoglin is required to maintain normal cardiac function in adult life2015
Dr Simon Tual-Chalot
Professor Helen Arthur
Mouse models of hereditary hemorrhagic telangiectasia: recent advances and future challenges2015
Dr Simon Tual-Chalot
Circulating microparticles from obstuctive sleep apnea syndrome patients induce endothelin-mediated angiogenesis2014
Dr Simon Tual-Chalot
Dr Marwa Mahmoud
Kathleen Allinson
Dr Rachael Redgrave
Professor Helen Arthur
et al.
Endothelial Depletion of Acvrl1 in Mice Leads to Arteriovenous Malformations Associated with Reduced Endoglin Expression2014
Dr Simon Tual-Chalot
Dr Rachael Redgrave
Professor Helen Arthur
Endothelial expression of endoglin and Acvrl1 are required for normal vascular patterning during developmental angiogenesis and for maintaining adult vessel integrity2014
Dr Simon Tual-Chalot
Kathleen Allinson
Professor Helen Arthur
Whole Mount Immunofluorescent Staining of the Neonatal Mouse Retina to Investigate Angiogenesis In vivo2013
Dr Simon Tual-Chalot
Circulating microparticles from patients with obstructive sleep apnea enhance vascular contraction: mandatory role of the endothelium2012
Dr Simon Tual-Chalot
Increased microparticle production and impaired microvascular endothelial function in aldosterone-salt-treated rats: protective effects of polyphenols2012
Dr Simon Tual-Chalot
Microparticle release in remote ischemic conditioning mechanism2012
Dr Simon Tual-Chalot
Increased oxidative stress induces apoptosis in human cystic fibrosis cells.2011
Dr Simon Tual-Chalot
Microparticles: targets and tools in cardiovascular disease2011
Dr Simon Tual-Chalot
Microvesicles: intercellular vectors of biological messages.2011
Dr Simon Tual-Chalot
Nocturnal release of leukocyte-derived microparticles in males with obstructive sleep apnoea.2011
Dr Simon Tual-Chalot
Circulating microparticles from pulmonary hypertensive rats induce endothelial dysfunction.2010
Dr Simon Tual-Chalot
PPARα is essential for microparticle-induced differentiation of mouse bone marrow-derived endothelial progenitor cells and angiogenesis2010