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Browsing publications by Dr Rachel Queen.

Newcastle AuthorsTitleYearFull text
Dr Joseph Collin
Dr Agata Rozanska
Dr Veronika Boczonadi
Marina Moya Molina
Adrienne Unsworth
et al.
Deciphering the spatio-temporal transcriptional and chromatin accessibility of human retinal organoid development at the single cell level2024
Dr Valeria Chichagova
Dr Maria Georgiou
Madeleine Carter
Dr Gerrit Hilgen
Dr Joseph Collin
et al.
Incorporating microglia-like cells in human induced pluripotent stem cell-derived retinal organoids2023
Lefteris Zormpas
Dr Rachel Queen
Dr Simon Cockell
Mapping the transcriptome: Realizing the full potential of spatial data analysis2023
Dr Joseph Collin
Dr Megan Hasoon
Zerti Zerti
Sarah Hammadi
Professor David Steel
et al.
Single-cell RNA sequencing reveals transcriptional changes of human choroidal and retinal pigment epithelium cells during fetal development, in healthy adult and intermediate age-related macular degeneration2023
Dr Rachel Queen
Spatial Gene Expression Changes in the Mouse Heart After Base-targeted Irradiation2023
Dr Rachel Queen
Moira Crosier
Dr Lorraine Eley
Dr Janet Kerwin
Jasmin Turner
et al.
Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves2023
Robert Jackson
Catherine Hatton
Dr Jarmila Spegarova
Dr Maria Georgiou
Dr Iram Haq
et al.
Conjunctival epithelial cells resist productive SARS-CoV-2 infection2022
Dr Maria Georgiou
Alex Chaudhary
Dr Joseph Collin
Dr Rachel Queen
Dr Birthe Hilgen
et al.
Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: A Comprehensive Validation Using Drugs and Compounds Affecting the Retina2022
Dr Agata Rozanska
Rodrigo Cerna Chavez
Dr Rachel Queen
Dr Joseph Collin
Dr Darin Zerti
et al.
pRB-depleted pluripotent stem cell retinal organoids recapitulate cell state transitions of retinoblastoma development and suggest an important role for pRB in retinal cell differentiation2022
Dr Marzena Kurzawa-Akanbi
Dr Florence Burte
Dr Birthe Hilgen
Dr Rachel Queen
Dr Jonathan Coxhead
et al.
Retinal pigment epithelium extracellular vesicles are potent inducers of age-related macular degeneration disease phenotype in the outer retina2022
Ramada Khasawneh
Dr Ralf Kist
Dr Rachel Queen
Raf Hussain
Dr Jonathan Coxhead
et al.
Msx1 haploinsufficiency modifies the Pax9-deficient cardiovascular phenotype2021
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Dr Sanja Bojic
Nicky Moyse
et al.
A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells2021
Dr Laura Jardine
Dr Simone Webb
Issac Goh
Dr Gary Reynolds
Dr Michael Mather
et al.
Blood and immune development in human fetal bone marrow and Down syndrome2021
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Professor David Steel
Professor Majlinda Lako
et al.
Dissecting the transcriptional and chromatin accessibility heterogeneity of proliferating cone precursors in human retinoblastoma tumours by single cell sequencing- opening pathways to new therapeutic strategies?2021
Professor Lyle Armstrong
Dr Joseph Collin
Dr Islam Mostafa
Dr Rachel Queen
Professor Francisco Figueiredo
et al.
In the eye of the storm: SARS-CoV-2 infection and replication at the ocular surface?2021
Dr Rachel Queen
Professor Majlinda Lako
Zerti Zerti
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics2021
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Dr Birthe Hilgen
Maria Georgiou
et al.
Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface2020
Dr Urszula Cytlak-Chaudhuri
Dr Anastasia Resteu
Sarah Pagan
Dr Kile Green
Dr Paul Milne
et al.
Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans2020
Dr Rachel Queen
Professor Majlinda Lako
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes2020
Dr Rachel Queen
Dr Darin Zerti
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes2020
Dr Olivier Govaere
Dr Simon Cockell
Dr Dina Tiniakos
Dr Rachel Queen
Dr Massimo Younes
et al.
Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis2020
Dr Rachel Queen
Dr Simon Cockell
Professor Majlinda Lako
Understanding the complexity of retinal and pluripotent stem cell derived retinal organoids with single cell RNA sequencing: current progress, remaining challenges and future prospectives2020
Hannah O'Keefe
Dr Rachel Queen
Dr Phillip Lord
Dr Joanna Elson
What can a comparative genomics approach tell us about the pathogenicity of mtDNA mutations in human populations?2020
Dr Joseph Collin
Dr Darin Zerti
Dr Rachel Queen
Dr Roman Bauer
Dr Jonathan Coxhead
et al.
CRX Expression in Pluripotent Stem Cell‐Derived Photoreceptors Marks a Transplantable Subpopulation of Early Cones2019
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Dr Birthe Hilgen
Raf Hussain
et al.
Deconstructing Retinal Organoids: Single cell RNA-Seq reveals the cellular components of human pluripotent stem cell-derived retina2019
Dr Carla Jackson
Dr Joseph Collin
Dr Rachel Queen
Dr Birthe Hilgen
Dr Darin Zerti
et al.
Systematic Comparison of Retinal Organoid Differentiation from Human Pluripotent Stem Cells Reveals Stage Specific, Cell Line, and Methodological Differences2019
Dr Sanja Bojic
Dr Dean Hallam
Nuno Alcada
Dr Ali Ghareeb
Dr Rachel Queen
et al.
CD200 expression marks a population of quiescent limbal epithelial stem cells with holoclone forming ability2018
Hannah O'Keefe
Dr Rachel Queen
Dr Phillip Lord
Dr Joanna Elson
Haplogroup Context is Less Important in the Penetrance of Mitochondrial DNA Complex I Mutations Compared to mt-tRNA Mutations2018
Dr Rachel Queen
Dr Jannetta Steyn
Dr Phillip Lord
Dr Joanna Elson
Mitochondrial DNA sequence context in the penetrance of mitochondrial t-RNA mutations: A study across multiple lineages with diagnostic implications2017