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Browsing publications by Professor Ian Hickson.

Newcastle AuthorsTitleYearFull text
Islam Al-Khawaldeh
Dr Christine Basmadjian
Dr Cinzia Bordoni
Dr Suzannah Harnor
Amy Heptinstall
et al.
An alkynylpyrimidine-based covalent inhibitor that targets a unique cysteine in NF-κB-inducing kinase (NIK)2021
Professor Ian Hickson
Discovery of JNJ-63576253, a next-generation androgen receptor antagonist active against wild-type and clinically relevant ligand binding domain mutations in metastatic castration-resistant prostate cancer2021
Professor Ian Hickson
Discovery of JNJ-63576253: A Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC)2021
Professor Ian Hickson
Dr Natalie Tatum
FEN1 Blockade for Platinum Chemo-Sensitization and Synthetic Lethality in Epithelial Ovarian Cancers2021
Professor Ian Hickson
Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors2021
Professor Ian Hickson
USP45 and Spindly are part of the same complex implicated in cell migration2018
Professor Ian Hickson
Substituted Thiohydantoin Derivatives as Androgen Receptor Antagonists2017
Professor Ian Hickson
The fluorescent two-hybrid assay for live-cell profiling of androgen receptor modulators2017
Professor Ian Hickson
A high-throughput PPI assay to quantify inhibition of androgen receptor variant 7 (AR-V7) binding to canonical AR full-length (AR-FL) binding partners2016
Professor Ian Hickson
Live-cell profiling of inhibitors targeting the N/C interaction within the androgen receptor2015
Professor Ian Hickson
USP45 deubiquitylase controls ERCC1-XPF endonuclease mediated DNA damage responses2015
Professor Ian Hickson
In vitro co-culture model to study adrenal stimulus of CRPC2014
Professor Ian Hickson
Adrenal stimulation of CRPC growth in an in vitro co-culture model.2014
Professor Ian Hickson
Complex in vitro and in vivo prostate cancer models for the PREDECT consortium2014
Professor Ian Hickson
Disrupting p53:Mdm2 and p53:Mdm4 - Comparative cell-based assays for drug screening2014
Professor Ian Hickson
Initial testing (stage 1) of the histone deacetylase inhibitor, quisinostat (JNJ-26481585), by the Pediatric Preclinical Testing Program2014
Professor Ian Hickson
The Fluorescent Two-Hybrid Assay to Screen for Protein–Protein Interaction Inhibitors in Live Cells: Targeting the Interaction of p53 with Mdm2 and Mdm42014