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Browsing publications by Dr Lei Huang.

Newcastle AuthorsTitleYearFull text
Dr Lei Huang
Correction to: Cervical squamous cell carcinoma-secreted exosomal miR-221-3p promotes lymphangiogenesis and lymphatic metastasis by targeting VASH1 (Oncogene, (2019), 38, 8, (1256-1268), 10.1038/s41388-018-0511-x)2022
Nga Vo
Dr Lei Huang
Dual pH-Responsive and Tumor-Targeted Nanoparticle-Mediated Anti-Angiogenesis siRNA Delivery for Tumor Treatment2022
Dr Lei Huang
Multifunctional nanoparticles co-loaded with Adriamycin and MDR-targeting siRNAs for treatment of chemotherapy-resistant esophageal cancer2022
Dr Lei Huang
Cancer-secreted exosomal miR-1468-5p promotes tumor immune escape via the immunosuppressive reprogramming of lymphatic vessels2021
Catherine Hatton
Dr Rachel Botting
Dr Maria Duenas Fadic
Dr Iram Haq
Dr Bernard Verdon
et al.
Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-22021
Dr Lei Huang
Emeritus Professor Andrew Mellor
Exosome-derived miR-142-5p remodels lymphatic vessels and induces IDO to promote immune privilege in the tumour microenvironment2021
Nga Vo
Dr Lei Huang
Emeritus Professor Andrew Mellor
Dr Katarina Novakovic
Genipin‐crosslinked chitosan hydrogels: Preliminary evaluation of the in vitro biocompatibility and biodegradation2021
Dr Ola Kamala
Dr Thomas Hallam
Tom Cox
Dr Yi Yang
Dr Falguni Vyas
et al.
Homodimeric Minimal Factor H: In Vivo Tracking and Extended Dosing Studies in Factor H Deficient Mice2021
Dr Lei Huang
Emeritus Professor Andrew Mellor
Indoleamine 2,3 dioxygenase, age, and immune activation in people living with HIV2021
Dr Lei Huang
Emeritus Professor Andrew Mellor
STING Negatively Regulates Allogeneic T-Cell Responses by Constraining Antigen-Presenting Cell Function2021
Dr Daniel Lin
Dr Lei Huang
James O'Hara
Emerita Professor Janet Wilson
Emeritus Professor Andrew Mellor
et al.
The immunotherapeutic role of indoleamine 2,3-dioxygenase in head and neck squamous cell carcinoma: A systematic review2021
Dr Lei Huang
Emeritus Professor Andrew Mellor
A Validation Study on IDO Immune Biomarkers for Survival Prediction in Non–Small Cell Lung Cancer: Radiation Dose Fractionation Effect in Early-Stage Disease2020
Dr Lei Huang
Emeritus Professor Andrew Mellor
CD40 Accelerates the Antigen-Specific Stem-Like Memory CD8+ T Cells Formation and Human Papilloma Virus (HPV)-Positive Tumor Eradication2020
Dr Lei Huang
Emeritus Professor Andrew Mellor
CD73 on cancer-associated fibroblasts enhanced by the A2B-mediated feedforward circuit enforces an immune checkpoint2020
Dr Henrique De Paula Lemos
Dr Rong Ou
Dr Caroline McCardle
Dr Lei Huang
Emeritus Professor Andrew Mellor
et al.
Co-treatments to boost IDO activity and inhibit production of downstream catabolites induce durable suppression of Experimental Autoimmune Encephalomyelitis2020
Dr Rong Ou
Dr Caroline McCardle
Jack Minett
Dr Lei Huang
Emeritus Professor Andrew Mellor
et al.
Overcoming resistance to STING agonist therapy to incite durable protective antitumor immunity2020
Nga Vo
Dr Lei Huang
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Dr Katarina Novakovic
et al.
Poly(ethylene glycol)‐interpenetrated genipin‐crosslinked chitosan hydrogels: Structure, pH responsiveness, gelation kinetics, and rheology2020
Dr Lei Huang
Emeritus Professor Andrew Mellor
Adoptive CD8+ T cell therapy against cancer:Challenges and opportunities 2019
Dr Lei Huang
Cervical Squamous Cell Carcinoma-secreted Exosomal miR-221-3p Promotes Lymphangiogenesis and Lymphatic Metastasis by Targeting VASH12019
Dr Henrique De Paula Lemos
Dr Lei Huang
Emeritus Professor Andrew Mellor
Immune control by amino acid catabolism during tumorigenesis and therapy2019
Dr Lei Huang
Emeritus Professor Andrew Mellor
Limited effect of indolamine 2,3-dioxygenase expression and enzymatic activity on lupus-like disease in b6.Nba2 mice2019
Emeritus Professor Andrew Mellor
Dr Lei Huang
Metabolic requirements for expanding and arming a clone army2019
Nga Vo
Dr Lei Huang
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Dr Katarina Novakovic
et al.
Smart chitosan-based hydrogels for targeted drug delivery applications2019
Dr Henrique De Paula Lemos
Dr Lei Huang
Dr Rong Ou
Emeritus Professor Andrew Mellor
Stimulator of Interferon Genes Agonists attenuate type I diabetes progression in NOD mice2019
Dr Lei Huang
Identification of novel α-fetoprotein specific T cell receptors to redirect T cells for hepatocellular carcinoma immunotherapy2018
Dr Lei Huang
Emeritus Professor Andrew Mellor
IDO Immune Status after Chemoradiation May Predict Survival in Lung Cancer Patients2018
Nga Vo
Dr Lei Huang
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Dr Katarina Novakovic
et al.
Smart chitosan-based hydrogels for targeted drug delivery application2018
Dr Henrique De Paula Lemos
Dr Lei Huang
Emeritus Professor Andrew Mellor
Carbidopa, a drug in use for management of Parkinson disease inhibits T cell activation and autoimmunity2017
Emeritus Professor Andrew Mellor
Dr Henrique De Paula Lemos
Dr Lei Huang
Indoleamine 2,3-Dioxygenase and tolerance: Where Are We Now?2017
Emeritus Professor Andrew Mellor
Dr Henrique De Paula Lemos
Dr Lei Huang
Indoleamine 2,3-Dioxygenase and Tolerance: Where Are We Now?2017
Dr Lei Huang
The Antitumor Effects of Vaccine-Activated CD8+ T Cells Associate with Weak TCR Signaling and Induction of Stem-Like Memory T Cells2017
Dr Lei Huang
Emeritus Professor Andrew Mellor
An essential role of Ffar2 (Gpr43) in dietary fibre-mediated promotion of healthy composition of gut microbiota and suppression of intestinal carcinogenesis2016
Dr Henrique De Paula Lemos
Dr Lei Huang
Dr Rong Ou
Emeritus Professor Andrew Mellor
STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation2016
Dr Lei Huang
Dr Rong Ou
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase2016
Dr Lei Huang
Amino Acid Metabolism Inhibits Antibody-Driven Kidney Injury by Inducing Autophagy2015
Dr Henrique De Paula Lemos
Dr Lei Huang
Emeritus Professor Andrew Mellor
STING, nanoparticles, autoimmune disease and cancer: a novel paradigm for immunotherapy?2015
Dr Lei Huang
Emeritus Professor Andrew Mellor
The PTEN pathway in Tregs is a critical driver for the suppressive tumor microenvironment2015
Dr Henrique De Paula Lemos
Dr Lei Huang
Emeritus Professor Andrew Mellor
Activation of the STING Adaptor Attenuates Experimental Autoimmune Encephalitis.2014
Dr Henrique De Paula Lemos
Dr Lei Huang
Emeritus Professor Andrew Mellor
Cytosolic DNA sensing via the stimulator of interferon genes adaptor: Yin and Yang of immune responses to DNA2014
Dr Henrique De Paula Lemos
Dr Lei Huang
Emeritus Professor Andrew Mellor
Immunosuppressive Myeloid Cells Induced by Chemotherapy Attenuate Antitumor CD4+ T-Cell Responses through the PD-1-PD-L1 Axis2014
Dr Lei Huang
Emeritus Professor Andrew Mellor
Metabolic control of tumour progression and antitumour immunity.2014
Dr Lei Huang
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Cutting Edge: DNA Sensing via the STING Adaptor in Myeloid Dendritic Cells Induces Potent Tolerogenic Responses2013
Dr Lei Huang
Emeritus Professor Andrew Mellor
Induction and role of indoleamine 2,3 dioxygenase in mouse models of influenza a virus infection2013
Dr Lei Huang
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Altered tryptophan metabolism as a paradigm for good and bad aspects of immune privilege in chronic inflammatory diseases2012
Dr Lei Huang
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Amino acid catabolism: a pivotal regulator of innate and adaptive immunity2012
Dr Lei Huang
Dr Henrique De Paula Lemos
Emeritus Professor Andrew Mellor
Engineering DNA Nanoparticles as Immunomodulatory Reagents that Activate Regulatory T Cells2012