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Browsing publications by Dr Birthe Hilgen.

Newcastle AuthorsTitleYearFull text
Dr Maria Georgiou
Alex Chaudhary
Dr Joseph Collin
Dr Rachel Queen
Dr Birthe Hilgen
et al.
Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: A Comprehensive Validation Using Drugs and Compounds Affecting the Retina2022
Dr Darin Zerti
Marina MoyaMolina
Dr Birthe Hilgen
Dr Roman Bauer
Professor Majlinda Lako
et al.
IGFBPs mediate IGF-1’s functions in retinal lamination and photoreceptor development during pluripotent stem cell differentiation to retinal organoids2021
Dr Darin Zerti
Dr Birthe Hilgen
Dr Joseph Collin
Professor Lyle Armstrong
Professor Evelyne Sernagor
et al.
Transplanted pluripotent stem cell‐derived photoreceptor precursors elicit conventional and unusual light responses in mice with advanced retinal degeneration2021
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Dr Birthe Hilgen
Maria Georgiou
et al.
Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface2020
Dr Darin Zerti
Dr Birthe Hilgen
Majed Felemban
Dr Ali Ghareeb
Dr Min Yu
et al.
Developing a simple method to enhance the generation of cone and rod photoreceptors in pluripotent stem cell‐derived retinal organoids 2020
Dr Maria Georgiou
Dr Valeria Chichagova
Dr Birthe Hilgen
Professor Evelyne Sernagor
Professor Lyle Armstrong
et al.
Room temperature shipment does not affect the biological activity of pluripotent stem cell-derived retinal organoids2020
Dr Carla Jackson
Dr Roman Bauer
Dr Joseph Collin
Dr Birthe Hilgen
Dr Darin Zerti
et al.
An integrated transcriptional analysis of the developing human retina2019
Majed Felemban
Dr Birthe Hilgen
Dr Darin Zerti
Dr Nicola Hunt
Dr Dean Hallam
et al.
Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids2019
Dr Joseph Collin
Dr Rachel Queen
Dr Darin Zerti
Dr Birthe Hilgen
Raf Hussain
et al.
Deconstructing Retinal Organoids: Single cell RNA-Seq reveals the cellular components of human pluripotent stem cell-derived retina2019
Dr Valeria Chichagova
Dr Birthe Hilgen
Majed Felemban
Dr Maria Georgiou
Professor Lyle Armstrong
et al.
Differentiation of Retinal Organoids from Human Pluripotent Stem Cells2019
Dr Carla Jackson
Dr Joseph Collin
Dr Rachel Queen
Dr Birthe Hilgen
Dr Darin Zerti
et al.
Systematic Comparison of Retinal Organoid Differentiation from Human Pluripotent Stem Cells Reveals Stage Specific, Cell Line, and Methodological Differences2019
Dr Valeria Chichagova
Dr Dean Hallam
Dr Joseph Collin
Dr Darin Zerti
Dr Birthe Hilgen
et al.
Cellular regeneration strategies for macular degeneration: past, present and future2018
Majed Felemban
Dr Birthe Hilgen
Dr Nicola Hunt
Dr Dean Hallam
Dr Darin Zerti
et al.
Extracellular matrix components expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix2018
Dr Dean Hallam
Dr Birthe Hilgen
Dr Lili Zhu
Dr Min Yu
Dr Sanja Bojic
et al.
Human induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient dependent efficiency2018
Dr Birthe Hilgen
Majed Felemban
Alex Sharpe
Dr Roman Bauer
Dr Dean Hallam
et al.
Laminin γ3 plays an important role in retinal lamination, photoreceptor organisation and ganglion cell differentiation2018
Dr Joseph Collin
Dr Carla Jackson
Dr Birthe Hilgen
Professor Majlinda Lako
Using Zinc Finger Nuclease Technology to Generate CRX-Reporter Human Embryonic Stem Cells as a Tool to Identify and Study the Emergence of Photoreceptors Precursors During Pluripotent Stem Cell Differentiation2016
Dr Birthe Hilgen
Connexin50 couples axon terminals of mouse horizontal cells by homotypic gap junctions2015
Majed Felemban
Dr Nicola Hunt
Dr Birthe Hilgen
Dr Carla Mellough
Professor Majlinda Lako
et al.
Investigation of extracellular matrix (ECM) component expression in developing retina2015
Professor Majlinda Lako
Dr Joseph Collin
Dr Carla Jackson
Dr Birthe Hilgen
Using zinc finger nuclease technology to generate reporter-labelled human pluripotent stem cells as a tool to optimize photoreceptor transplantation2015
Dr Gerrit Hilgen
Dr Birthe Hilgen
AII amacrine cells discriminate between heterocellular and homocellular locations when assembling connexin36-containing gap junctions2014
Dr Katarina Kranz
Dr Birthe Hilgen
Expression of Pannexin1 in the outer plexiform layer of the mouse retina and physiological impact of its knockout2013
Dr Birthe Hilgen
Ablation of Retinal Horizontal Cells from Adult Mice Leads to Rod Degeneration and Remodeling in the Outer Retina2012