Publications by Professor David Jones - ePrints

Browsing publications by Professor David Jones.

Newcastle Authors	Title	Year
Professor David Jones Dr David Sheridan	A phase II, randomized, open-label, 52-week study of seladelpar in patients with primary biliary cholangitis	2022
Professor David Jones	Ten years of NIHR research training: who got an award? A retrospective cohort study	2022
Colette Kirk Laura Haigh Dr Nicholas Thompson Professor Mark Pearce Professor David Jones et al.	The effects of different parenteral nutrition lipid formulations on clinical and laboratory endpoints in patients receiving home parenteral nutrition: A systematic review	2022
Professor David Jones	UK-PBC National Audit: A collaborative success in identifying critical shortfalls	2022
Professor Heather Cordell James Fryett Dr Rebecca Darlay Professor David Jones	An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs	2021
Dr Jess Dyson Professor David Jones	Bezafibrate for the Treatment of Cholestatic Pruritus: Time for a Change in Management?	2021
Professor Heather Cordell Dr Rebecca Darlay Professor David Jones	Corrigendum to ‘An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs’ [J Hepatol 2021;75(3):572–581] (Journal of Hepatology (2021) 75(3) (572–581), (S0168827821003342), (10.1016/j.jhep.2021.04.055))	2021
Stephen Rice Dr Viviana Albani Dr Dimitrios Minos Dr Gulnar Fattakhova Dr Mark Shirley et al.	Effects of Primary Biliary Cholangitis on Quality of Life and Health Care Costs in the United Kingdom	2021
Dr April Phaw Dr Jess Leighton Dr Jess Dyson Professor David Jones	Managing cognitive symptoms and fatigue in cholestatic liver disease	2021
Dr Jess Leighton Dr Jess Dyson Professor David Jones	Patient ownership of primary biliary cholangitis long-Term management	2021
Dr Laura Jopson Professor David Jones	Quality of life in patients with primary biliary cholangitis: A cross-geographical comparison	2021
Dr Aaron Wetten Professor David Jones Dr Jess Dyson	Specific considerations for the management of primary biliary cholangitis: are the drug treatment options good enough?	2021
Dr Alistair Leitch Dr Ibrahim Ibrahim Dr Tarek Mamdouh Abdelghany Dr Alex Charlton Clair Roper et al.	The methylimidazolium ionic liquid M8OI is detectable in human sera and is subject to biliary excretion in perfused human liver	2021
Dr Ben Barron-Millar Dr Laura Ogle Professor John Kirby Dr Jeremy Palmer Dr Laura Jopson et al.	The Serum Proteome and Ursodeoxycholic Acid Response in Primary Biliary Cholangitis	2021
Dr April Phaw Dr Jess Dyson Professor David Jones	Understanding Fatigue in Primary Biliary Cholangitis	2021
Professor David Jones	Widespread gaps in the quality of care for primary biliary cholangitis in UK	2021
Professor Heather Cordell Professor David Jones Dr Harumasa Nakamura	X Chromosome Contribution to the Genetic Architecture of Primary Biliary Cholangitis	2021
Dr Helen Bosomworth Professor David Jones	Editorial: rapid assessment of health-related quality of life in primary biliary cholangitis—no excuse not to ask. Authors' reply	2020
Dr April Phaw Dr Jess Dyson Professor David Jones	Emerging drugs for the treatment of primary biliary cholangitis	2020
Professor David Jones	Letter: histology is relevant for risk stratification in primary biliary cholangitis	2020
Dr Dennis Lendrem Dr Clare Lendrem Dr Arthur Pratt Professor John Isaacs Professor David Jones et al.	Schrödinger's pipeline and the outsourcing of pharmaceutical innovation	2020
Dr John Brain Professor David Jones	TGF-β2 silencing to target biliary-derived liver diseases	2020
Dr Alistair Leitch Dr Tarek Mamdouh Abdelghany Dr Phillip Probert Dr Stephanie Meyer Dr Jeremy Palmer et al.	The toxicity of the methylimidazolium ionic liquids, with a focus on M8OI and hepatic effects	2020
Dr Jess Dyson Professor David Jones	UDCA prophylaxis for post-transplant PBC recurrence prevention: Time to change practice	2020
Dr Vinod Hegade Dr Stuart Kendrick Professor David Jones	Autotaxin, bile acid profile and effect of ileal bile acid transporter inhibition in primary biliary cholangitis patients with pruritus	2019
Dr Jess Dyson Professor David Jones	British Society of Gastroenterology and UK-PSC guidelines for the diagnosis and management of primary sclerosing cholangitis	2019
Dr Vinod Hegade Professor David Jones	Complications of cholestasis	2019
Professor David Jones	Development and adaptation of patient-reported outcome measures for patients who experience itch associated with primary biliary cholangitis	2019
Professor David Jones	Fatigue in chronic liver disease: New insights and therapeutic approaches	2019
Dr Amardeep Khanna Dr Vinod Hegade Professor David Jones	Management of Fatigue in Primary Biliary Cholangitis	2019
Dr April Phaw Professor David Jones	PBC: Better Solutions to Beat Feeling Beat	2019
Professor David Jones	Position statement on access to care in rare liver diseases: Advancements of the European reference network (ERN) RARE-LIVER	2019
Dr Vinod Hegade Dr Holly Fisher Dr Stuart Kendrick Professor David Jones	Pruritus Is Common and Undertreated in Patients With Primary Biliary Cholangitis in the United Kingdom	2019
Dr Amaani Hussain Robert Samuel Dr Vinod Hegade Professor David Jones Professor Nick Reynolds et al.	Pruritus secondary to primary biliary cholangitis: a review of the pathophysiology and management with phototherapy	2019
Dr Amardeep Khanna Dr Laura Jopson Denise Howel Andrew Bryant Professor Andrew Blamire et al.	Rituximab is Ineffective for Treatment of Fatigue in Primary Biliary Cholangitis: A Phase-2 Randomised Controlled Trial	2019
Matthew Simcock Dr Sirintra Nakjang Dr Richard Heath Dr Lauren Walker Dr Craig Robson et al.	The Pioneering Role of GATA2 in Androgen Receptor Variant Regulation Is Controlled by Bromodomain and Extraterminal Proteins in Castrate-Resistant Prostate Cancer	2019
Professor David Jones	Access to care in rare liver diseases: New challenges and new opportunities	2018
Dr Rebecca Darlay Dr Kristin Ayers Dr Lynsey Hall Professor David Jones Professor Heather Cordell et al.	Amino acid residues in five separate HLA genes can explain most of the known associations between the MHC and Primary Biliary Cholangitis	2018
Dr Laura Jopson Dr Amardeep Khanna Professor David Jones	Are Clinicians Ready for Safe Use of Stratified Therapy in Primary Biliary Cholangitis (PBC)? A Study of Educational Awareness	2018
Professor David Jones Dr Vinod Hegade	Bezafibrate in primary biliary cholangitis	2018
Dr Phillip Probert Dr Alistair Leitch Dr Michael Dunn Dr Stephanie Meyer Dr Jeremy Palmer et al.	Identification of a xenobiotic as a potential environmental trigger in primary biliary cholangitis	2018
Professor David Jones	Increased sensitivity of Treg cells from patients with PBC to low dose IL-12 drives their differentiation into IFN-γ secreting cells	2018
Dr Jess Dyson Dr Lin Lee Wong Dr Theophile Bigirumurame Dr Stuart Kendrick Professor David Jones et al.	Inequity of care provision and outcome disparity in autoimmune hepatitis in the United Kingdom	2018
Dr Jess Dyson Professor David Jones Dr Mark Hudson	Primary sclerosing cholangitis	2018
Dr Amardeep Khanna Dr Laura Jopson Denise Howel Andrew Bryant Professor Andrew Blamire et al.	Rituximab for the Treatment of Fatigue in Primary Biliary Cholangitis (formerly Primary Biliary Cirrhosis) A Randomised Controlled Trial	2018
Dr Amardeep Khanna Dr Jess Leighton Dr Lin Lee Wong Professor David Jones	Symptoms of PBC – Pathophysiology and management	2018
Dr Jess Dyson Dr Dina Tiniakos Professor David Jones	The British Society of Gastroenterology/UK-PBC primary biliary cholangitis treatment and management guidelines	2018
Dr Lin Lee Wong Dr Holly Fisher Dr Deborah Stocken Stephen Rice Dr Amardeep Khanna et al.	The Impact of Autoimmune Hepatitis and Its Treatment on Health Utility	2018
Dr James Orr Dr Dave Houghton Professor David Jones	A novel method for continuous, non-invasive, cuff-less measurement of blood pressure: Evaluation in patients with non-alcoholic fatty liver disease	2017
Dr Chris Lamb Dr John Mansfield Anna Long Maria Price Dr Graeme O'Boyle et al.	aEß7 Integrin Identifies Subsets of Pro-Inflammatory Colonic CD4+ T Lymphocytes in Ulcerative Colitis	2017
Dr Vinod Hegade Professor David Jones	Apical Sodium-Dependent Transporter Inhibitors in Primary Biliary Cholangitis and Primary Sclerosing Cholangitis	2017
Dr Vinod Hegade Dr Stuart Kendrick Professor David Jones	Effect of ileal bile acid transporter inhibitor GSK2330672 on pruritus in primary biliary cholangitis: a double-blind, randomised, placebo-controlled, crossover, phase 2a study	2017
Dr Amardeep Khanna Professor David Jones	Novel strategies and therapeutic options for the management of primary biliary cholangitis	2017
Professor David Jones	Seladelpar (MBX-8025), a selective PPAR-δ agonist, in patients with primary biliary cholangitis with an inadequate response to ursodeoxycholic acid: a double-blind, randomised, placebo-controlled, phase 2, proof-of-concept study	2017
Professor David Jones	Stratified medicine and primary biliary cholangitis	2017
Dr Lin Lee Wong Dr Vinod Hegade Professor David Jones	What Comes after Ursodeoxycholic Acid in Primary Biliary Cholangitis?	2017
Professor David Jones	A phase 2 proof of concept study of MBX-8025 in patients with Primary Biliary Cholangitis (PBC) who are inadequate responders to ursodeoxycholic acid (UDCA)	2016
Dr Vinod Hegade Dr Stuart Kendrick Professor David Jones	A Phase 2 Randomised Crossover Trial of Ileal Bile Acid Transporter Inhibitor GSK2330672 in Patients with Primary Biliary Cholangitis and Symptoms of Pruritus	2016
Dr Vinod Hegade Dr Stuart Kendrick Professor David Jones	A systematic approach to the management of cholestatic pruritus in primary biliary cirrhosis	2016
Dr Gary Reynolds Dr Lin Lee Wong Professor David Jones Dr Jess Dyson	Balance between exhausted regulatory T cells and CD161(+) NK cells is crucial in acute AIH pathogenesis	2016
Dr Vinod Hegade Dr Stuart Kendrick Professor David Jones	BAT117213: Ileal bile acid transporter (IBAT) inhibition as a treatment for pruritus in primary biliary cirrhosis: study protocol for a randomised controlled trial	2016
Professor Luke Vale Dr Diarmuid Coughlan Professor David Jones	Clinician Confidence in Stratifying Risk in Primary Biliary Cirrhosis - A UK-PBC Survey	2016
Stephen Rice Dr Viviana Albani Dr Gulnar Fattakhova Professor Stephen Rushton Dr Diarmuid Coughlan et al.	Cost and utility estimates for patients at different stages in the natural history of Primary Biliary Cirrhosis (PBC) from the UK-PBC Cohort	2016
Kile Green Dr Laura Jopson Dr Ben Barron-Millar Barbara Innes Sarah Pagan et al.	Early Molecular Stratification of High-risk Primary Biliary Cholangitis	2016
Dr Jess Dyson Professor David Jones	Early Primary Biliary Cholangitis is Characterised by Brain Abnormalities on Cerebral Magnetic Resonance Imaging	2016
Professor David Jones	Editorial: fenofibrate as second-line therapy in high risk PBC - more answers or more questions?	2016
Professor David Jones	Efficacy and Safety of Obeticholic Acid (OCA) in PBC Patients with Advanced Disease as Evidenced by Abnormal Bilirubin: An Integrated Analysis	2016
Professor David Jones	Efficacy of Obeticholic Acid Treatment in Patients with Primary Biliary Cholangitis with Cirrhosis	2016
Dr James Orr Dr Daniel Stow Professor Fiona Matthews Professor Barbara Hanratty Professor David Jones et al.	Eleven-year mortality and referral practices associated with abnormal alanine aminotransferase (ALT) results	2016
Professor Luke Vale Professor David Jones	Hospitalisation for PBC: a UK-PBC analysis of hospital episodes	2016
Dr Vinod Hegade Dr Amardeep Khanna Dr Lucy Walker Dr Lin Lee Wong Dr Jess Dyson et al.	Long-Term Fenofibrate Treatment in Primary Biliary Cholangitis Improves Biochemistry but Not the UK-PBC Risk Score	2016
Dr Vinod Hegade Dr Richard Speight Rachel Etherington Professor David Jones	Novel bile acid therapeutics for the treatment of chronic liver diseases	2016
Professor David Jones	Obeticholic acid for the treatment of primary biliary cirrhosis	2016
Professor David Jones	POISE: A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis	2016
Professor David Jones	Predicted Risk of End Stage Liver Disease with Continued Standard of Care and Subsequent Addition of Obeticholic Acid in Patients with PBC	2016
Dr Phillip Probert Dr Jeremy Palmer Dr Aimen Amer Steven White Professor David Jones et al.	Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1′-hydroxyestragole to a genotoxic species via a SULT2B1-dependent mechanism	2016
Dr Jess Dyson Dr Nina Wilson Dr Laura Jopson Samantha Ducker Dr Deborah Stocken et al.	The inter-relationship of symptom severity and quality of life in 2055 patients with primary biliary cholangitis	2016
Dr Vinod Hegade Professor David Jones	The safety and efficacy of nasobiliary drainage in the treatment of refractory cholestatic pruritus: a multicentre European study	2016
Professor Heather Cordell Professor David Jones	The UK-PBC Risk Scores: Derivation and Validation of a Scoring System for Long-Term Prediction of End-Stage Liver Disease in Primary Biliary Cholangitis	2016
Dr Lin Lee Wong Dr Stuart Kendrick Professor David Jones Dr Jess Dyson	UK-AIH - Highlighting the need for standardization of treatment in autoimmune hepatitis	2016
Dr Laura Jopson Dr Jess Dyson Professor David Jones	Understanding and Treating Fatigue in Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis	2016
Dr Jess Dyson Dr Jeremy Palmer Dr Lin Lee Wong Dr Stuart Kendrick Professor David Jones et al.	Understanding the importance of pro- and anti-inflammatory cytokines in autoimmune hepatitis	2016
Dr Lin Lee Wong Dr Stuart Kendrick Dr Jess Dyson Professor David Jones	Understanding the unmet need in Autoimmune Hepatitis - The United Kingdom AIH Study (UK-AIH)	2016
Dr Vinod Hegade Dr Stuart Kendrick Professor David Jones	A Comparative Study of Pruritus in PBC Cohorts from UK, USA and Italy	2015
Professor David Jones	A phase 3B, double blind, placebo controlled study evaluating the effect of obeticholic acid on clinical outcomes in subjects with primary biliary cirrhosis at elevated risk of progression to liver transplant or death	2015
Dr Vinod Hegade Dr Stuart Kendrick Professor David Jones	A study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of repeat doses of GSK2330672 administration in subjects with primary biliary cirrhosis and symptoms of pruritus	2015
Dr Katherine James Shereen Al-Ali Dr Jessica Tarn Dr Simon Cockell Dr Colin Gillespie et al.	A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren’s Syndrome	2015
Professor David Jones	Changing nomenclature for PBC: From "cirrhosis' to "cholangitis'	2015
Professor David Jones	Changing nomenclature for PBC: from 'cirrhosis' to 'cholangitis'	2015
Professor David Jones	Changing Nomenclature for PBC: From 'Cirrhosis' to 'Cholangitis'	2015
Professor David Jones	Changing nomenclature for PBC: From 'cirrhosis' to 'cholangitis'	2015
Professor David Jones	Changing nomenclature for PBC: From 'cirrhosis' to 'cholangitis'	2015
Professor David Jones	Changing Nomenclature for PBC: From 'Cirrhosis' to 'Cholangitis'	2015
Professor David Jones	Changing nomenclature for PBC: From 'cirrhosis' to 'cholangitis'	2015
Professor David Jones	Changing Nomenclature for PBC: From 'Cirrhosis' to 'Cholangitis'	2015
Professor David Jones	Cholestatic liver disease and liver transplantation in the UK: a twenty year review	2015
Professor Luke Vale Dr Diarmuid Coughlan Professor David Jones	Clinician confidence in stratifying risk in primary biliary cirrhosis - a UK-PBC survey	2015
Dr Vinod Hegade Professor David Jones	Complications of cholestasis	2015
Professor David Jones	Convergence of Two Predictive Models of Risk Reduction in Patients with Primary Biliary Cirrhosis (PBC)	2015
Greta Pells Professor David Jones Professor Luke Vale	Cost-effectiveness of current therapies in primary biliary cirrhosis: a systematic review of economic evidence	2015
Dr Vinod Hegade Dr Stuart Kendrick Professor David Jones	Drug treatment of pruritus in liver diseases	2015
Professor David Jones	Efficacy and Safety of Obeticholic Acid (OCA) in PBC Patients with Advanced Disease as Evidenced by Abnormal Bilirubin: An Integrated Analysis	2015
Dr Laura Jopson Professor David Jones	Fatigue in Primary Biliary Cirrhosis: Prevalence, Pathogenesis and Management	2015
Dr Jess Dyson Dr Ahmed Elsharkawy Dr Chris Lamb Dr Ahmad Al-Rifai Professor Julia Newton et al.	Fatigue in primary sclerosing cholangitis is associated with sympathetic over-activity and increased cardiac output	2015
Kile Green Sarah Pagan Dr Jess Dyson Dr Lucy Walker Dr Laura Jopson et al.	High-risk primary biliary cirrhosis has a distinct molecular signature opening the way for a molecular approach to stratified therapeutics	2015
Professor Luke Vale Professor David Jones	Hospitalisation for primary biliary cirrhosis: a UK-PBC analysis of hospital episodes	2015
Dr Rebecca Darlay Dr Kristin Ayers Professor David Jones Dr Peter Donaldson Professor Heather Cordell et al.	Immunochip analysis identifies amino acid residues in five separate HLA genes driving the association between the MHC and primary biliary cirrhosis	2015
Dr Vinod Hegade Dr Stuart Kendrick Professor David Jones	Itch and liver: management in primary care	2015
Dr James Orr Professor David Jones Dr Mark Hudson	Minimally deranged serum alanine transferase identified in the community: referral practices, prevalence of liver pathology and long term mortality	2015
Dr Laura Jopson Dr Vinod Hegade Professor David Jones	Natural history of fatigue and pruritus in primary biliary cirrhosis: Implications for the role of pruritus in the aetiology and treatment of fatigue	2015
Dr Jess Dyson Professor Derek Mann Professor David Jones	Novel therapeutic targets in primary biliary cirrhosis	2015
Dr Laura Jopson Professor Julia Newton Denise Howel Dr Jeremy Palmer Professor John Isaacs et al.	RITPBC: B-cell depleting therapy (RITUXIMAB) as a treatment for fatigue in primary biliary cirrhosis: study protocol for a randomised controlled trial	2015
Dr James Orr Dr Mark Hudson Emeritus Professor Calum McNeil Professor David Jones	The home study (home monitoring in encephalopathy): Rationale and study design	2015
Dr Jess Dyson Professor David Jones	Unmet clinical need in autoimmune liver diseases	2015
Professor David Jones	Validation of an alkaline phosphatase and bilirubin response criterion as biomarker for transplant-free	2015
Dr Jess Dyson Dr Laura Jopson Samantha Ducker Professor David Jones	Age at Presentation and Gender are Predictors of Increased Mortality Over Long-Term Follow-Up in Primary Biliary Cirrhosis (PBC)	2014
Professor Kofi Oppong Professor David Jones Richard Charnley Professor Derek Manas Bryon Jaques et al.	Autoimmune Pancreatitis - Diagnosis, Management and Longterm Follow-up	2014
Dr James Orr Dr Mark Hudson Professor David Jones	Development and validation of The Newcastle Patient Reported Ascites Measure	2014
Dr Jess Dyson Professor David Jones	Diagnosis and Management of Patients with primary biliary cirrchosis	2014
Dr Imran Patanwala Dr Maria King Dr John Rose Professor David Jones	Folic acid handling by the human gut: implications for food fortification and supplementation	2014
Professor David Jones Dr Chris Vincent	FXR Agonist Obeticholic Acid: Pruritus, A Common Side Effect Ameliorated by Dose Titration	2014
Dr James Orr Tara Homer Dr Laura Ternent Professor Julia Newton Emeritus Professor Calum McNeil et al.	Health related quality of life in people with advanced chronic liver disease	2014
Dr James Orr Tara Homer Dr Laura Ternent Professor Julia Newton Emeritus Professor Calum McNeil et al.	'Health Related Quality of Life in People with Advanced Chronic Liver Disease'	2014
Dr James Frith Professor Fai Ng Professor Chris Day Dr Brendan Payne Professor Neil Sheerin et al.	Orthostatic intolerance is common in chronic disease - A clinical cohort study	2014
Dr Laura Jopson Professor David Jones	Pathogenesis of Primary Biliary Cirrhosis and Its Fatigue	2014
Dr Vinod Hegade Dr Stuart Kendrick Professor David Jones	Patient Experience and Characteristics of Cholestatic Pruritus in the UK-PBC Research Cohort	2014
Professor David Jones	PBC management among clinicians: Gaps in clinical competence and practice performance - Survey findings	2014
Professor David Jones	Reply to: "Fatigue and liver transplantation in patients with primary biliary cirrhosis"	2014
Dr Laura Jopson Professor David Jones Professor Heather Cordell	Risk stratification in primary biliary cirrhosis using the UK-PBC Research Cohort	2014
Dr Jess Dyson Dr Laura Jopson Samantha Ducker Professor David Jones	The Impact of Age at Presentation on Symptoms in Primary Biliary Cirrhosis	2014
Dr Laura Jopson Dr Jess Dyson Professor David Jones	The New Epidemiology of Primary Biliary Cirrhosis	2014
Dr Chris Lamb Dr John Mansfield Dr Graeme O'Boyle Professor David Jones Jennifer Kirby et al.	Ulcerative colitis: The alpha E beta 7 integrin is associated with a high frequency of Th17, Th1 and Th17/Th1 CD4 lymphocytes	2014
Dr Chris Lamb Dr John Mansfield Dr Graeme O'Boyle Professor David Jones Dr Michael Keir et al.	Ulcerative Colitis: The Alpha-e-beta-7 Integrin Is Associated With A High Frequency Of Th17, Th1 And Th17/th1 Cd4 Lymphocytes	2014
Dr Jeremy Palmer Professor David Jones Dr Jess Dyson Professor John Kirby	Understanding the Mechanisms Underpinning Treatment Non-Response in Primary Biliary Cirrhosis: A Tool for Treatment Stratification	2014
Dr Jeremy Palmer Dr Jess Dyson Professor David Jones Professor John Kirby	Understanding the mechanisms underpinning treatment non-response in Primary Biliary Cirrhosis: a tool for treatment stratification	2014
Dr Laura Jopson Professor David Jones Dr Jess Dyson	Younger patients presenting with Primary Biliary Cirrhosis are more likely to have cognitive impairment	2014
Dr Imran Patanwala Dr Peter McMeekin Professor Julia Newton Professor David Jones	A validated clinical tool for the prediction of varices in PBC: The Newcastle Varices in PBC Score	2013
Greta Pells Professor Julia Newton Professor David Jones	Age at Diagnosis Predicts Treatment Response in Primary Biliary Cirrhosis (PBC)	2013
Chris Elliott Dr James Frith Professor Chris Day Professor David Jones Professor Julia Newton et al.	Functional Impairment in Alcoholic Liver Disease and Non-alcoholic Fatty Liver Disease Is Significant and Persists over 3 Years of Follow-Up	2013
Professor David Jones Dr James Frith Professor Julia Newton	Reduced thoracic fluid content in early-stage primary biliary cirrhosis that associates with impraired cardiac inotropy	2013
Dr Kirstie Anderson Professor David Jones Katharine Wilton Professor Julia Newton	Restless leg syndrome is a treatable cause of sleep disturbance and fatigue in primary biliary cirrhosis	2013
Greta Pells Professor Julia Newton Samantha Ducker Professor David Jones	Sex and Age Are Determinants of the Clinical Phenotype of Primary Biliary Cirrhosis and Response to Ursodeoxycholic Acid	2013
Dr Laura Jopson Professor David Jones	The effect of liver transplantation on fatigue in patients with primary biliary cirrhosis: A prospective study	2013
Greta Pells Professor Julia Newton Samantha Ducker Professor David Jones	The impact of liver transplantation on the phenotype of primary biliary cirrhosis patients in the UK-PBC cohort	2013
Professor Julia Newton Samantha Ducker Professor David Jones	The impact of primary biliary cirrhosis on perceived quality of life: The UK-PBC national study	2013
Dr Chris Lamb Dr Graeme O'Boyle Professor David Jones Dr John Mansfield Professor John Kirby et al.	Blockade of the B7 integrin prevents adherence of t lymphocytes to MAdCAM-1 in an in vitro model of vascular microcirculation post-capillary shear flow	2012
Dr Kieren Hollingsworth Dr Guy MacGowan Dr Matt Bates Professor Roy Taylor Professor David Jones et al.	Cardiac torsion-strain relationships in fatigued primary biliary cirrhosis patients show accelerated aging: a pilot cross-sectional study	2012
Dr James Frith Professor David Jones Professor Chris Day Professor Julia Newton	Cognitive impairment in non-cirrhotic chronic liver disease is unrelated to liver disease severity but associated with ineffective baroreflex function	2012
Professor Heather Cordell Samantha Ducker Dr Peter Donaldson Professor David Jones	Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis	2012
Professor Heather Cordell Samantha Ducker Dr Peter Donaldson Professor David Jones	Dense fine-mapping study identifies novel disease loci and implicates coding and non-coding variation in primary Mary cirrhosis risk	2012
Dr James Frith Sandra Kerr Dr Lisa Robinson Chris Elliott Katharine Wilton et al.	Falls and Fall-Related Injury Are Common in Older People with Chronic Liver Disease	2012
Dr Marie Hale Professor Julia Newton Professor David Jones	Fatigue in primary biliary cirrhosis	2012
Professor David Jones Dr Sally Stephens Dr Laura Yates Dr Amanda Greenall Professor Simon Thomas et al.	Fetal Outcomes Following Dosulepin Overdose in Pregnancy	2012
Professor David Jones Dr Sally Stephens Dr Laura Yates Dr Amanda Greenall Professor Simon Thomas et al.	Fetal Outcomes Following Fentanyl Exposure in Pregnancy	2012
Professor David Jones Dr Kieren Hollingsworth Professor Djordje Jakovljevic Dr Gulnar Fattakhova Jessie Pairman et al.	Loss of capacity to recover from acidosis on repeat exercise in chronic fatigue syndrome: A case control study	2012
Professor David Jones	Out-patient' albumin dialysis for cholestatic patients with intractable pruritus	2012
Professor David Jones	Pathogenesis of cholestatic itch: Old questions, new answers, and future opportunities	2012
Professor David Jones Professor Heather Cordell	Pathway analysis of the UK GWAS dataset implicates key immunoregulatory pathways in the pathogenesis of primary biliary cirrhosis	2012
Dr Michael Prentis Professor Mike Trenell Professor David Jones Tim Lees Dr Christopher Snowden et al.	Submaximal exercise testing predicts perioperative hospitalization after aortic aneurysm repair	2012
Dr Imran Patanwala Professor Julia Newton Professor David Jones	The clinical impact of varices and a new externally validated non-invasive inexpensive tool to predict their presence in patients with PBC	2012
Dr Imran Patanwala Professor Julia Newton Dr Mark Hudson Professor David Jones	The clinical impact of varices and a new externally validated non-invasive inexpensive tool to predict their presence in patients with PBC	2012
Professor David Jones	The Farnesoid X receptor (FXR) agoinst obeticholic acid (OCA) increases plasma FGF-19 concentrations and decreases bile acid synthesis in primary biliary cirrhosis (PBC)	2012
Professor David Jones	A potential retroviral aetiology for mouse PBC: More answers or more questions?	2011
Dr Imran Patanwala Dr Simon Kometa Professor Julia Newton Dr Mark Hudson Professor David Jones et al.	An externally-validated clinical tool for the prediction of gastro-oesophageal varices in patients with PBC - the Newcastle varices in PBC (NVP) score	2011
Professor David Jones	An international study evaluating the farnesoid X receptor agonist obeticholic acid as montherapy in PBC	2011
Professor David Jones Dr Imran Patanwala Professor Julia Newton	Comparison of the PBC-40 and PBC-27 tools for quality of life assessment in English speaking primary biliary cirrhosis patients	2011
Professor David Jones Jo Gray Dr James Frith Professor Julia Newton	Fatigue severity remains stable over time and independently associated with orthostatic symptoms in chronic fatigue syndrome: a longitudinal study	2011
Professor Julia Newton Dr James Frith Jessie Pairman Professor David Jones	Functional capacity is significantly impaired in primary biliary cirrhosis and is related to orthostatic symptoms	2011
Professor Heather Cordell Dr Peter Donaldson Samantha Ducker Professor David Jones	Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis	2011
Dr James Prentis Professor David Jones Professor Mike Trenell Dr Christopher Snowden	Impaired cardiorespiratory reserve in primary biliary cirrhosis patients undergoing liver transplant assessment	2011
Professor Julia Newton Dr Mark Hudson Professor David Jones	Morbidity and mortality associated with varices in patients with primary biliary cirrhosis	2011
Emeritus Professor Nick Miller Dr Katherine Deane Professor David Jones Emma Noble	National survey of speech and language therapy provision for people with Parkinson’s disease in the United Kingdom: therapists’ practices	2011
Dr Chris Lamb Maria Price Professor David Jones Dr John Mansfield	Patients with Crohn's Disease report high levels of fatigue during a symptomatic disease flare	2011
Chris Elliott Dr James Frith Jessie Pairman Professor David Jones Professor Julia Newton et al.	Reduction in functional ability is significant postliver transplantation compared with matched liver disease and community dwelling controls	2011
Professor David Jones Professor Julia Newton	Reply to: Do fatigue and UDCA therapy truly have independent effects on mortality in PBC?	2011
Emeritus Professor Nick Miller Emma Noble Professor David Jones Dr Katherine Deane	Survey of speech and language therapy provision for people with Parkinson’s disease in the United Kingdom: patients’ and carers’ perspectives	2011
Professor David Jones Professor Julia Newton	The Complexity of Fatigue	2011
Professor David Jones Dr Ahmad Al-Rifai Dr James Frith Dr Imran Patanwala Professor Julia Newton et al.	The independent effects of fatigue and UDCA therapy on mortality in primary biliary cirrhosis: Results of a 9 year cohort follow-up (vol 53, pg 911, 2010) [Corrigendum]	2011
Dr Timothy Hardy Dr Claire McDonald Professor David Jones Professor Julia Newton	A follow-up study of modafinil for the treatment of daytime somnolence and fatigue in primary biliary cirrhosis	2010
Professor David Jones Dr Kieren Hollingsworth Professor Roy Taylor Professor Andrew Blamire Professor Julia Newton et al.	Abnormalities in pH handling by peripheral muscle and potential regulation by the autonomic nervous system in chronic fatigue syndrome	2010
Dr Stuart Kendrick Dr Graeme O'Boyle Professor Jelena Mann Dr Mujdat Zeybel Dr Jeremy Palmer et al.	Acetate, the Key Modulator of Inflammatory Responses in Acute Alcoholic Hepatitis	2010
Dr Jeremy Palmer Dr Imran Patanwala Elsbeth Henderson Professor Chris Day Professor David Jones et al.	Allo- and auto-antibody responses in ALD as biomarkers of prognosis	2010
Dr Claire McDonald Professor Julia Newton Professor Stuart Baker Professor David Jones	Central nervous system dysfunction in primary biliary cirrhosis and its relationship to symptoms	2010
Professor Heather Cordell Dr Peter Donaldson Professor David Jones	Genome-wide association study identifies more than 10 primary biliary cirrhosis risk loci	2010
Professor David Jones Dr Kieren Hollingsworth Dr Gulnar Fattakhova Dr Guy MacGowan Professor Roy Taylor et al.	Impaired cardiovascular function in primary biliary cirrhosis	2010
Dr Kieren Hollingsworth Professor David Jones Professor Roy Taylor Professor Andrew Blamire Professor Julia Newton et al.	Impaired cardiovascular response to standing in Chronic Fatigue Syndrome	2010
Dr Kieren Hollingsworth Professor David Jones Professor Roy Taylor Dr James Frith Professor Andrew Blamire et al.	Impaired cerebral autoregulation in primary biliary cirrhosis: implications for the pathogenesis of cognitive decline	2010
Dr Kieren Hollingsworth Professor Julia Newton Dr Imran Patanwala Professor Roy Taylor Professor Andrew Blamire et al.	Impaired subendocardial myofibre in primary biliary cirrhosis	2010
Dr James Frith Chris Elliott Jessie Pairman Dr Imran Patanwala Professor David Jones et al.	Liver transplantation is not associated with significant improvement in functional ability or symptoms	2010
Dr Kieren Hollingsworth Professor Julia Newton Professor Roy Taylor Professor Andrew Blamire Professor David Jones et al.	Loss of capacity to recover from acidosis in repeat exercise is strongly associated with fatigue in primary biliary cirrhosis	2010
Professor Julia Newton Professor David Jones	Making sense of fatigue	2010
Dr James Frith Professor Chris Day Chris Elliott Professor David Jones Professor Julia Newton et al.	Potential strategies to improve uptake of exercise interventions in non-alcoholic fatty liver disease	2010
Dr James Frith Sandra Kerr Dr Lisa Robinson Chris Elliott Katharine Wilton et al.	Primary biliary cirrhosis is associated with falls and significant fall related injury	2010
Dr James Frith Dr Simon Kerr Dr Lisa Robinson Katharine Wilton Jessie Pairman et al.	Primary biliary cirrhosis is associated with falls and significant fall related injury	2010
Professor Julia Newton Professor David Jones	Reply	2010
Dr Karolina Rygiel Dr Helen Robertson Dr Joe Willet Dr John Brain Professor Alastair Burt et al.	T Cell-Mediated Biliary Epithelial-to-Mesenchymal Transition in Liver Allograft Rejection	2010
Professor David Jones Dr Ahmad Al-Rifai Dr James Frith Dr Imran Patanwala Professor Julia Newton et al.	The independent effects of fatigue and UDCA therapy on mortality in primary biliary cirrhosis: Results of a 9 year follow-up	2010
Professor David Jones Professor Chris Day	The significance of autoantibodies in non-alcoholic fatty liver disease	2010
Dr Stuart Kendrick Elsbeth Henderson Dr Jeremy Palmer Professor David Jones Professor Chris Day et al.	Theophylline improves steroid sensitivity in acute alcoholic hepatitis	2010
Professor Heather Cordell Samantha Ducker Dr Peter Donaldson Professor David Jones	Validation of the north american genome-wide association study of primary biliary cirrhosis and identification of additional genetic susceptibility loci in a British cohort	2010
Professor Julia Newton Professor David Jones	Variability of perceived fatigue in primary biliary cirrhosis: implications for symptom assessment	2010
Professor Alastair Burt Professor David Jones	1001 Cytochome P450 2E1 (CYP2E1) autoreactivity in alcoholic liver disease: No evidence for a pathogenetic role	2009
Dr Jeremy Palmer Dr Hannah Walden Professor John Kirby Professor David Jones	680: Incorporation of 6-bromohexanoic acid (6BH) into cellular pyruvate dehydrogenase complex (PDC): Further evidence for generation of an autoimmunogenic neoantigen in primary billary cirrhosis (PBC)	2009
Professor David Jones Dr Claire McDonald Professor Julia Newton	A Efficacy and Tolerability of Modafinil for the Treatment of Daytime Somnolence and Fatigue in Primary Biliary Cirrhosis	2009
Dr James Frith Professor David Jones Professor Julia Newton	Chronic liver disease in an ageing population	2009
Dr Lucy Walker Professor Julia Newton Professor David Jones Professor Margaret Bassendine	Comment on Biochemical Response to Ursodeoxycholic Acid and Long-Term Prognosis in Primary Biliary Cirrhosis	2009
Professor Julia Newton Jessie Pairman Katharine Wilton Professor David Jones Professor Chris Day et al.	Fatigue and autonomic dysfunction in non-alcoholic fatty liver disease	2009
Dr Kieren Hollingsworth Professor David Jones Dr Benjamin Aribisala Professor Peter Thelwall Professor Roy Taylor et al.	Globus pallidus magnetisation transfer ratio, T1 and T2 in primary biliary cirrhosis: relationship with disease stage and age	2009
Dr Kieren Hollingsworth Professor Julia Newton Professor Andrew Blamire Professor Roy Taylor Professor David Jones et al.	Loss of Capacity to Recover from Acidosis on Repeat Exercise is Strongly Associated with Fatigue in Primary Biliary Cirrhosis (PBC)	2009
Professor Julia Newton Jessie Pairman Professor David Jones	Lower Ambulatory Blood Pressure in Chronic Fatigue Syndrome	2009
Sam Stevens Professor John Allen Emeritus Professor Alan Murray Professor David Jones Professor Julia Newton et al.	Microvascular optical assessment confirms the presence of peripheral autonomic dysfunction in primary biliary cirrhosis	2009
Professor David Jones Dr Janine Gray Professor Julia Newton	Perceived fatigue is comparable between different disease groups	2009
Dr James Frith Professor David Jones Professor Julia Newton	Regulation of Cerebral Blood Flow is Significantly Impaired in Primary Biliary Cirrhosis	2009
Professor Julia Newton Professor David Jones	Serum anti-mitochondrial antibodies and fatigue in primary biliary cirrhosis	2009
Professor Julia Newton Jessie Pairman Katharine Wilton Professor David Jones	A Predictive Model for Fatigue and Its Etiologic Associations in Primary Biliary Cirrhosis	2008
Professor David Jones Jessie Pairman Katharine Wilton Professor Julia Newton	An integrated care pathway improves quality of life in Primary Biliary Cirrhosis	2008
Professor Julia Newton Dr James Frith Dr Lisa Robinson Professor David Jones	Appreciation of the benefits of exercise programmes in non-alcoholic liver disease: implications of fatigue and impact upon activities of daily living	2008
Professor Julia Newton Dr Kieren Hollingsworth Professor Andrew Blamire Professor Roy Taylor Ruth Pearce et al.	Autonomic dysfunction: A potential modifiable risk factor for cognitive decline in primary biliary cirrhosis	2008
Dr Helen Marshall Dr Helen Robertson Professor Alastair Burt Professor David Jones Professor John Kirby et al.	Biliary epithelial to mesenchymal transition contributes to portal tract fibrogenesis in primary sclerosing cholangitis	2008
Professor Julia Newton Dr Kieren Hollingsworth Professor Roy Taylor Ruth Pearce Professor Andrew Blamire et al.	Cognitive impairment in primary biliary cirrhosis: Symptom impact and potential etiology	2008
Dr Stuart Kendrick Dr Graeme O'Boyle Dr Jeremy Palmer Professor David Jones	Enhanced inflammatory responses in alcoholic liver disease: is acetate the key?	2008
Professor John Kirby Dr Helen Robertson Dr Helen Marshall Dr Karolina Rygiel Dr Mark Hudson et al.	Epithelial to mesenchymal transition in primary sclerosing cholangitis	2008
Professor John Kirby Dr Helen Robertson Helen Marshall Dr Karolina Rygiel Dr Mark Hudson et al.	Epithelial to mesenchymal transition in primary sclerosing cholangitis	2008
Dr Karolina Rygiel Dr Helen Robertson Dr Helen Marshall Marcin Pekalski Liena Zhao et al.	Epithelial-mesenchymal transition contributes to portal tract fibrogenesis during human chronic liver disease	2008
Professor David Jones Professor Lynn Rochester	Every day walking with Parkinson’s disease: Understanding personal challenges and strategies	2008
Dr James Frith Dr Lisa Robinson Jessie Pairman Katharine Wilton Professor David Jones et al.	Falls are common in primary biliary cirrhosis and associate with dysautonomia and distal lower limb weakness	2008
Professor Julia Newton Jessie Pairman Katharine Wilton Professor David Jones	Fatigue in non-alcoholic fatty liver disease (NAFLD) associates with hypotension and autonomic dysfunction	2008
Professor Julia Newton Professor David Jones Katharine Wilton Professor Alastair Burt Professor Chris Day et al.	Fatigue in non-alcoholic fatty liver disease (NAFLD) is significant and associates with inactivity and excessive daytime sleepiness but not with liver disease severity or insulin resistance	2008
Dr Kieren Hollingsworth Professor David Jones Dr Benjamin Aribisala Professor Roy Taylor Professor Andrew Blamire et al.	Globus pallidus abnormalities in MRI T2 relaxation time in primary biliary cirrhosis are associated with impaired cerebral autoregulation: implications for the pathogenesis of cognitive decline	2008
Dr Jeremy Palmer Professor David Jones Professor John Kirby	Human Th17 cells: investigation of T cell differentiation in the presence of TGF-beta and a range of pro-inflammatory cytokines	2008
Professor David Jones Professor Lynn Rochester Victoria Hetherington	Identifying fallers with Parkinson's disease using home-based tests: Who is at risk?	2008
Professor Julia Newton Dr Kieren Hollingsworth Dr Jeremy Palmer Professor Roy Taylor Professor Andrew Blamire et al.	Mitochondrial dysfunction and muscle PH abnormality post-exercise: A two-hit mechanism for fatigue pathogenesis in primary biliary cirrhosis	2008
Dr James Frith Professor Dame Louise Robinson Jessie Pairman Katharine Wilton Professor David Jones et al.	Orthostatic grading scale is better than timed up and go at identifying fallers with primary biliary cirrhosis	2008
Professor David Jones	Pathogenesis of Primary Biliary Cirrhosis	2008
Professor David Jones	Pathogenesis of primary biliary cirrhosis	2008
Dr Kieren Hollingsworth Professor Julia Newton Professor Roy Taylor Dr Claire McDonald Dr Jeremy Palmer et al.	Pilot Study of Peripheral Muscle Function in Primary Biliary Cirrhosis: Potential Implications for Fatigue Pathogenesis	2008
Professor David Jones Dr Jeremy Palmer Professor Alastair Burt Professor John Kirby	The specificity of liver inflammation in mouse models of primary biliary cirrhosis	2008
Sam Stevens Emeritus Professor Alan Murray Professor David Jones Professor Julia Newton	Vascular optical assessment of peripheral autonomic dysfunctino (AD) in primary biliary cirrhosis	2008
Dr Hannah Walden Professor John Kirby Emeritus Professor Steve Yeaman Dr Joseph Gray Professor David Jones et al.	Xenobiotic Incorporation into Pyruvate Dehydrogenase Complex Can Occur Via the Exogenous Lipoylation Pathway	2008
Dr Martin Prince Professor Margaret Bassendine Dr Mark Hudson Emeritus Professor Oliver James Professor David Jones et al.	A randomized trial of antioxidant therapy alone or with corticosteroids in acute alcoholic hepatitis	2007
Professor David Jones Professor Julia Newton	An open study of modafinil for the treatment of daytime somnolence and fatigue in primary biliary cirrhosis	2007
Professor David Jones Professor Julia Newton	An open study of modafinil for the treatment of daytime somnolence and fatigue in primary biliary cirrhosis	2007
Professor David Jones Professor Julia Newton	Association between fatigue and decreased survival in primary biliary cirrhosis - Reply	2007
Professor David Jones Professor Julia Newton	Authors' reply [2]	2007
Professor Julia Newton Dr Simon Kerr Jessie Pairman Professor David Jones	Autonomic dysfunction in primary biliary cirrhosis correlates with fatigue severity	2007
Dr Helen Robertson Professor John Kirby Professor David Jones Professor Alastair Burt	Biliary epithelial-mesenchymal transition in posttransplantation recurrence of primary biliary cirrhosis	2007
Dr Claire McDonald Professor David Jones Professor Julia Newton	Central cerebral activation is reduced in primary biliary cirrhosis and associated with excessive daytime sleepiness	2007
Professor David Jones	Complications of cholestasis	2007
Dr Peter Donaldson Professor David Jones Dr John Taylor Professor Julia Newton Professor Margaret Bassendine et al.	Cytotoxic T-Lymphocyte-Associated Antigen-4 Single Nucleotide Polymorphisms and Haplotypes in Primary Biliary Cirrhosis	2007
Dr Graeme O'Boyle Professor David Jones Professor Chris Day	Effects of ethanol on endotoxin-mediated cytokine release: Sensitisation via TLR4 but normal tolerance	2007
Dr Stuart Kendrick Dr Graeme O'Boyle Professor Jelena Mann Professor David Jones Professor Chris Day et al.	Ethanol-induced histone acetylation: A novel mechanism for enhancement of inflammation in alcoholic hepatitis?	2007
Professor David Jones	Fatigue in cholestatic liver disease: Is it all in the mind?	2007
Professor Julia Newton Professor David Jones Elsbeth Henderson Jessie Pairman Katharine Wilton et al.	Fatigue in NAFLD is severe and associates with excessive daytime somnolence but not with liver disease severity or insulin resistance	2007
Professor David Jones Professor Julia Newton	Fatigue-associated mortality in Primary Biliary Cirrosis is principally a problem of the over 65’s.	2007
Dr Stuart Kendrick Dr Jeremy Palmer Professor David Jones Professor Chris Day	Lymphocyte steroid sensitivity in severe alcoholic hepatitis	2007
Dr Stuart Kendrick Professor David Jones	Mechanisms of Innate Immunity in Sepsis	2007
Professor David Jones	Pathogenesis of primary biliary cirrhosis	2007
Professor Julia Newton Dr Mark Hudson Jessie Pairman Professor David Jones	Population prevalence and symptom associations of autonomic dysfunction in primary biliary cirrhosis	2007
Professor Julia Newton Professor David Jones	Population prevalence of autonomic dysfunction in Primary Biliary Cirrhosis	2007
Dr Hannah Walden Dr Jeremy Palmer Professor John Kirby Dr Stuart Kendrick Professor David Jones et al.	Substrate promiscuity in the pyruvate dehydrogenase complex (PDC) lipoylation pathway: Xenobiotic incorporation as a potential mechanism for the pathogenesis of primary biliary cirrhosis (PBC)	2007
Professor Julia Newton Professor David Jones	Symptoms of autonomic dysfunction in chronic fatigue syndrome	2007
Professor Julia Newton Professor David Jones	Symptoms of autonomic dysfunction in chronic fatigue syndrome	2007
Professor Mark Freeston Dr Christine Baker Professor David Jones Professor Julia Newton	The role of psychological factors in the fatigue of primary biliary cirrhosis	2007
Professor David Jones Dr Amanda Robe Dr Jeremy Palmer Professor John Kirby	Adoptive transfer of self-PDC reactive T-cells into naive mice induces portal tract and bile duct changes characteristic of primary biliary cirrhosis (PBC)	2006
Professor David Jones	Anaesthesia for patients with chronic liver disease	2006
Professor Julia Newton Professor David Jones Katharine Wilton Jessie Pairman Dr Steve Parry et al.	Calcaneal bone mineral density in older patients who have fallen	2006
Professor Julia Newton Professor David Jones Katharine Wilton Jessie Pairman Dr Steve Parry et al.	Calcaneal bone mineral density in older patients who have fallen	2006
Professor Julia Newton Professor David Jones	Characterisation of the associations and impact of symptoms in primary biliary cirrhosis using a disease specific quality of life measure	2006
Professor David Jones Professor Julia Newton	Cognitive impairment in primary biliary cirrhosis (PBC) is related to sympathetic autonomic nervous system dysfunction	2006
Dr Karolina Rygiel Dr Helen Robertson Professor Alastair Burt Professor David Jones Professor John Kirby et al.	Demonstration of the transition of intrahepatic biliary epithelial cells to fibroblasts during chronic inflammatory liver diseases	2006
Professor Julia Newton Emeritus Professor John Gibson Katharine Wilton Professor David Jones	Fatigue in primary biliary cirrhosis is associated with excessive daytime somnolence	2006
Professor Julia Newton Jessie Pairman Professor David Jones	Fatigue in Primary Biliary Cirrhosis is Associated with Symptomatic Abnormalities in Blood Pressure Regulation	2006
Dr Jenny Milner Professor David Jones Professor David Young Emeritus Professor Drew Rowan Emeritus Professor Tim Cawston et al.	Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthritis	2006
Professor David Jones Dr Martin Prince Professor Julia Newton	Four year follow up of fatigue in a geographically defined primary biliary cirrhosis patient cohort	2006
Dr Peter Donaldson Dr Anna Baragiotta Professor David Jones Emeritus Professor Oliver James Professor Margaret Bassendine et al.	HLA class II alleles, genotypes, haplotypes, and amino acids in primary biliary cirrhosis: A large-scale study	2006
Professor Julia Newton Professor David Jones	Modafinil is an effective treatment for excessive daytime somnolence and fatigue in primary biliary cirrhosis (PBC)	2006
Anna McHugh Dr Amanda Robe Dr Jeremy Palmer Professor David Jones	PDC-E3BP is not a dominant T-cell autoantigen in primary biliary cirrhosis	2006
Professor David Jones Professor Julia Newton	Primary biliary cirrhosis	2006
Professor Julia Newton Professor David Jones	Reduced heart rate variability and baroreflex sensitivity in primary biliary cirrhosis	2006
Professor David Jones Professor Julia Newton	Reflections on therapeutic trials in primary biliary cirrhosis: A qualify of life oriented counter-view	2006
Professor Christopher Ward Dr Ian Forrest Professor David Jones Dr Gary Pritchard Rachel Stovold et al.	The phosphodiesterase type IV (PDE IV) inhibitor cilomilast decreases pro-inflammatory cytokine production from primary bronchial epithelial cells derived from lung transplant recipients	2006
Dr Anna Broad Professor David Jones Professor John Kirby	Toll-like receptor (TLR) response tolerance: A key physiological "damage limitation" Effect and an important potential opportunity for therapy	2006
Dr Anna Broad Professor John Kirby Professor David Jones	Toll-like receptor interactions: Tolerance of MyD88-dependent cytokines but enhancement of MyD88-independent interferon-β production	2006
Dr Amanda Robe Professor John Kirby Professor David Jones Dr Jeremy Palmer	A key role for autoreactive B cells in the breakdown of T-cell tolerance to pyruvate dehydrogenase complex in the mouse	2005
Dr Amanda Robe Professor John Kirby Professor David Jones Dr Jeremy Palmer	A key role for autoreactive B cells in the breakdown of T-cell tolerance to pyruvate dehydrogenase complex in the mouse	2005
Dr Mark Hudson Joanne Newton Dr Martin Prince Professor David Jones	An evidence-based model for the targeting of varices screening in PBC	2005
Dr Ann Jacoby Professor Julia Newton Emeritus Professor Oliver James Professor David Jones	Development, validation, and evaluation of the PBC-40, a disease specific health related quality of life measure for primary biliary cirrhosis	2005
Dr Ian Forrest Dr James Lordan Dr Gary Pritchard Professor David Jones Dr Helen Robertson et al.	Epithelial to mesenchymal transition in clinically stable lung transplant recipients	2005
Liena Zhao Dr Helen Robertson Professor John Kirby Professor David Jones Professor Alastair Burt et al.	Epithelial-mesenchymal transition in portal fibrosis	2005
Professor David Jones	Fat is an immuno-regulatory issue	2005
Dr Martin Prince Professor Margaret Bassendine Professor David Jones	Fatigue in primary biliary cirrhosis [1]	2005
Professor Julia Newton Professor David Jones	Fatigue in primary biliary cirrhosis is associated with symptoms of autonomic dysfunction	2005
Professor David Young Dr Rachel Lakey Professor David Jones Emeritus Professor Tim Cawston	Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption	2005
Professor Christopher Ward Dr Helen Robertson Dr Ian Forrest Dr James Lordan Denis Murphy et al.	Hypothesis: Epithelial-to-mesenchymal transition is a common cause of chronic allograft failure	2005
Dr Stephen Stewart Dr Beate Haugk Professor Alastair Burt Professor David Jones Professor Chris Day et al.	Anti-cytochrome P4502E1 autoantibody titre associates with immune liver histology in advanced alcoholic liver disease	2004
Dr Jeremy Palmer Professor John Kirby Professor David Jones	Apoptosis as a mechanism for cell surface expression of the autoantigen pyruvate dehydrogenase complex	2004
Dr Deborah Buck Professor David Jones Emeritus Professor Oliver James Dr Ann Jacoby	Assessing quality of life in primary biliary cirrhosis	2004
Dr Amanda Robe Dr Jeremy Palmer Professor John Kirby Professor David Jones	Breakdown of T-cell tolerance to the primary biliary cirrhosis (PBC) autoantigen pyruvate dehydrogenase complex is a B-cell driven process	2004
Dr Amanda Robe Dr Jeremy Palmer Professor John Kirby Professor David Jones	Breakdown of T-cell tolerance to the primary biliary cirrhosis (PBC) autoantigen pyruvate dehydrogenase complex is a B-cell driven process	2004
Dr Anna Baragiotta Dr Kaushik Agarwal Dr Alison Sutherland Professor David Jones Dr Peter Donaldson et al.	Chemokine receptor 5 and primary biliary cirrhosis: A two-centre genetic association study	2004
Dr Stephen Stewart Professor David Jones Dr Beate Haugk Professor Alastair Burt Professor Chris Day et al.	Correlation between anti-CYP2E1 titre and lymphocyte infiltration in ALD - An autoimmune disease in some patients?	2004
Dr Jeremy Palmer Dr Amanda Robe Professor Alastair Burt Professor John Kirby Professor David Jones et al.	Covalent modification as a mechanism for the breakdown of immune tolerance to pyruvate dehydrogenase complex in the mouse	2004
Professor Margaret Bassendine Professor David Jones	Fatigue and primary biliary cirrhosis: Association of globus pallidus magnetisation transfer ratio measurements with fatigue severity and blood manganese levels	2004
Dr Anna Baragiotta Dr Kaushik Agarwal Professor David Jones Dr Peter Donaldson Professor Margaret Bassendine et al.	No evidence for involvement of the CCR5 (chemokine receptor-5) delta 32 mutation in primary biliary cirrhosis	2004
Dr Stephen Stewart Professor Chris Day Professor David Jones	Oxidative Stress as a Trigger for Cellular Immune Responses in Patients with Alcoholic Liver Disease	2004
Emeritus Professor Oliver James Professor David Jones	Patterns of Autoimmunity in PBC Patients and Their Families: a Population-Based Cohort Study	2004
Emeritus Professor Oliver James Professor David Jones	Patterns of autoimmunity in primary biliary cirrhosis patients and their families: A population-based cohort study	2004
Professor David Jones	Primary biliary cirrhosis	2004
Professor David Jones Professor Margaret Bassendine	Primary biliary cirrhosis: Report of a focus study group	2004
Professor Julia Newton Professor David Jones	Risk factors for sudden cardiac death in primary biliary cirrhosis.	2004
Dr Martin Prince Dr Denis Burke Matthew Edwards Dr Michael Bramble Emeritus Professor Oliver James et al.	A placebo controlled randomised crossover trial of oral antioxidant supplementation for fatigue in primary biliary cirrhosis (PBC)	2003
Professor David Jones	Addison's other disease: Primary biliary cirrhosis as a model autoimmune disease	2003
Dr John Taylor Emeritus Professor Oliver James Professor Margaret Bassendine Professor David Jones Dr Peter Donaldson et al.	Caspase 8 gene polymorphism is associated with primary biliary cirrhosis	2003
Professor David Jones Professor John Kirby	Cell-surface expression of PDC during apoptosis: A possible route for autoantigen presentation in PBC?	2003
Professor David Jones	Discussion on the true impact of fatigue in primary biliary cirrhosis: A population study [1] (multiple letters)	2003
Professor Ann Daly Julian Leathart Dr Beate Haugk Professor David Jones Professor Alastair Burt et al.	Evidence that alcoholic liver disease is due to immune mechanisms in genetically susceptible drinkers	2003
Dr Martin Prince Professor David Jones	Fatigue in anti-mitochondrial antibody positive patients with normal liver function tests	2003
Professor David Jones	Fatigue in PBC	2003
Dr Stephen Stewart Professor Ann Daly Professor David Jones Julian Leathart Professor Chris Day et al.	Genetic and epigenetic factors in autoimmune reactions toward cytochrome P4502E1 in alcoholic liver disease	2003
Professor David Jones Dr Peter Donaldson	Genetic factors in the pathogenesis of primary biliary cirrhosis	2003
Anna McHugh Dr Jeremy Palmer Emeritus Professor Steve Yeaman Professor David Jones	Is PDC-E3BP (protein X) a T-cell autoantigen in primary biliary cirrhosis?	2003
Professor Chris Day Professor David Jones	Neo-antigen specific T-cell responses are closely associated with the presence of liver disease in heavy drinkers	2003
Dr Martin Prince Emeritus Professor Oliver James Professor David Jones	Oral antioxidant supplementation for fatigue associated with primary biliary cirrhosis	2003
Dr Martin Prince Dr Nia Edwards Dr Michael Bramble Emeritus Professor Oliver James Professor David Jones et al.	Oral antioxidant supplementation for fatigue associated with primary biliary cirrhosis: Results of a multicentre, randomized, placebo-controlled, cross-over trial	2003
Dr Martin Prince Emeritus Professor Oliver James Professor Chris Day Dr Mark Hudson Professor David Jones et al.	Pain as a complication of opiate antagonist therapy in cholestasis: A single centre experience	2003
Dr Martin Prince Dr Mark Hudson Professor Chris Day Emeritus Professor Oliver James Professor David Jones et al.	Pain as a complication of use of opiate antagonists for symptom control in cholestasis	2003
Professor David Jones	Pathogenesis of primary biliary cirrhosis	2003
Professor David Jones Dr Martin Prince Dr Mark Hudson	The Mayo prognostic score fails to predict increased mortality associated with portal hypertension in primary biliary cirrhosis (PBC)	2003
Professor John Kirby Michael Bone Dr Helen Robertson Dr Mark Hudson Professor David Jones et al.	The number of intraepithelial T cells decreases from ascending colon to rectum [1]	2003
Dr Amanda Robe Dr Jeremy Palmer Professor John Kirby Professor Margaret Bassendine Professor David Jones et al.	[abstract] Characterisation of liver infiltrating T-cell antigen specificity in a mouse model of primary biliary cirrhosis (PBC)	2002
Dr Martin Prince Dr Denis Burke Matthew Edwards Dr Michael Bramble Emeritus Professor Oliver James et al.	A placebo controlled randomised crossover trial of oral antioxidant supplementation for fatigue in primary biliary cirrhosis (PBC)	2002
Professor David Jones Dr Jeremy Palmer Professor Alastair Burt Dr Amanda Robe Professor John Kirby et al.	Bacterial motif DNA as an adjuvant for the breakdown of immune self-tolerance to pyruvate dehydrogenase complex	2002
Dr Jeremy Palmer Professor John Kirby Professor David Jones	Breakdown of tolerance is seen to both PDC-E2 and PDC-E3BP, individual antigens in primary biliary cirrhosis, in a mouse model of PDC autoreactivity	2002
Dr John Taylor Emeritus Professor Oliver James Professor Margaret Bassendine Professor David Jones Dr Peter Donaldson et al.	Caspase 8 gene polymorphism is associated with primary biliary cirrhosis	2002
Dr Pamela MacDonald Professor John Kirby Professor David Jones	Cell-surface expression of pyruvate dehydrogenase complex during apoptosis: A possible route for autoantigen presentation in primary biliary cirrhosis	2002
Dr Amanda Robe Dr Jeremy Palmer Professor John Kirby Professor David Jones	Characterisation of liver infiltrating T-cell antigen specificity in a mouse model of primary biliary cirrhosis (PBC)	2002
Professor David Jones	Complications of cholestasis	2002
Professor Ann Daly Julian Leathart Dr Beate Haugk Professor David Jones Professor Alastair Burt et al.	Evidence that alcoholic liver disease is due to immune mechanisms in genetically susceptible drinkers	2002
Dr Martin Prince Professor David Jones	Fatigue in anti-mitochondrial antibody positive patients with normal liver function tests	2002
Dr Kaushik Agarwal Professor David Jones Professor Alastair Burt Dr Mark Hudson Emeritus Professor Oliver James et al.	Metastatic breast carcinoma presenting as acute liver failure and portal hypertension	2002
Professor Chris Day Professor David Jones	Neo-antigen specific T-cell responses are closely associated with the presence of liver disease in heavy drinkers	2002
Professor David Jones Dr Jeremy Palmer Dr Amanda Robe Professor John Kirby	Oral tolerisation to pyruvate dehydrogenase complex as a potential therapy for primary biliary cirrhosis	2002
Professor Julia Newton Professor David Jones	Osteoporosis in primary biliary cirrhosis	2002
Professor Julia Newton Emeritus Professor Oliver James Professor Margaret Bassendine Professor David Jones	Osteoporosis is not a specific complication of primary biliary cirrhosis	2002
Dr Martin Prince Emeritus Professor Oliver James Professor Chris Day Dr Mark Hudson Professor David Jones et al.	Pain as a complication of opiate antagonist therapy in cholestasis: A single centre experience	2002
Dr Martin Prince Professor Margaret Bassendine Professor David Jones	Reduced pallidal magnetisation transfer ratios are associated with fatigue in pre-cirrhotic patients with primary biliary cirrhosis (PBC)	2002
Professor Margaret Bassendine Professor David Jones	Reduced pallidal magnetisation transfer ratios are associated with fatigue in pre-cirrhotic patients with primary biliary cirrhosis [abstract]	2002
Dr Jeremy Palmer Professor John Kirby Professor David Jones	The immunology of primary biliary cirrhosis: The end of the beginning?	2002
Professor David Jones Dr Martin Prince Dr Mark Hudson	The impact of portal hypertension in primary biliary cirrhosis (PBC)	2002
Professor David Jones Dr Martin Prince Dr Mark Hudson	The mayo prognostic score fails to predict increased mortality associated with portal hypertension in primary biliary cirrhosis	2002
Professor David Jones Dr Martin Prince Dr Mark Hudson	The prevalence of portal hypertension (PHT) in primary biliary cirrhosis (PBC) [abstract]	2002
Dr Martin Prince Dr Anna Baragiotta Professor Margaret Bassendine Emeritus Professor Oliver James Professor David Jones et al.	The true impact of fatigue in primary biliary cirrhosis: A population study	2002
Dr Stephen Stewart Professor Ann Daly Julian Leathart Professor David Jones Professor Chris Day et al.	A polymorphism in CTLA-4 is associated with the presence of anti-CYP2E1 antibody titres in patients with alcoholic liver disease	2001
Dr Stephen Stewart Professor David Jones Professor Chris Day	Alcoholic liver disease: New insights into mechanisms and preventative strategies	2001
Dr Jeremy Palmer Emeritus Professor Steve Yeaman Professor David Jones	Epitope specificity of anti-PDC E1 alpha antibodies in primary biliary cirrhosis (PBC)	2001
Emeritus Professor Oliver James Professor David Jones	Failure to sustain peripheral muscle activity as an aetiological factor for fatigue in primary biliary cirrhosis (PBC)	2001
Professor David Jones Professor Julia Newton	Fatigue in primary biliary cirrhosis is associated with early autonomic failure	2001
Dr Anna Baragiotta Professor David Jones Dr Kaushik Agarwal Emeritus Professor Oliver James Professor Margaret Bassendine et al.	Genetic susceptibility to primary biliary cirrhosis (PBC): Analysis of chemokine receptor 5 (CCR5) delta32 deletion	2001
Emeritus Professor Oliver James Professor David Jones	Grip strength and subjective fatigue in patients with primary biliary cirrhosis [4]	2001
Dr Peter Donaldson Dr Kaushik Agarwal Emeritus Professor Oliver James Professor David Jones	HLA and interleukin 1 gene polymorphisms in primary biliary cirrhosis: associations with disease progression and disease susceptibility	2001
Dr Martin Prince Professor David Jones	Measuring fatigue in medically unwell and distressed patients	2001
Dr David Neill David Hughes Alan Leake Louise Ward Professor David Jones et al.	Neuritogenic-neurotoxic effects of membrane-associated forms of amyloid precursor protein	2001
Professor Julia Newton Emeritus Professor Roger Francis Emeritus Professor Oliver James Professor Margaret Bassendine Professor David Jones et al.	Osteoporosis in primary biliary cirrhosis revisited	2001
Professor John Isaacs Professor David Jones	The ninety-fifth annual general meeting of the association of physicians of Great Britain and Ireland 2001	2001
Dr Kaushik Agarwal Dr John Rose Dr Mark Hudson Professor David Jones	TIPSS in PBC: Lessons regarding the role played by variceal bleeding in disease prognosis	2001
Dr Anna Baragiotta Emeritus Professor Oliver James Professor David Jones Joanne Newton Professor Margaret Bassendine et al.	Vitamin D receptor (VDR) TaqI polymorphism in primary biliary cirrhosis (PBC)	2001
Professor David Jones	Autoantigens in primary biliary cirrhosis	2000
Emeritus Professor Steve Yeaman Professor John Kirby Professor David Jones	Autoreactive responses to pyruvate dehydrogenase complex in the pathogenesis of primary biliary cirrhosis	2000
Professor David Jones Professor Ann Daly Emeritus Professor Oliver James Dr Bijayeswar Vaidya Professor Simon Pearce et al.	CTLA-4 gene polymorphism confers susceptibility to primary biliary cirrhosis	2000
Dr Kaushik Agarwal Professor David Jones Dr Peter Donaldson	Cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphisms and susceptibility to type 1 autoimmune hepatitis	2000
Dr Kaushik Agarwal Professor David Jones Dr Peter Donaldson	Cytotoxic T lymphocyte antigen-4 gene polymorphisms and susceptibility to type 1 autoimmune hepatitis	2000
Professor David Jones	Fetal microchimerism: an aetiological factor in primary biliary cirrhosis?	2000
Dr Martin Prince Professor David Jones	Primary biliary cirrhosis: New perspectives in diagnosis and treatment	2000
Professor David Jones	Recent advances in autoimmune diseases	2000
Dr Jeremy Palmer Professor John Kirby Emeritus Professor Steve Yeaman Professor Margaret Bassendine Professor David Jones et al.	Secretory autoantibodies in primary biliary cirrhosis (PBC)	2000
Dr Martin Prince Emeritus Professor Oliver James Professor David Jones	Validation of a fatigue impact score in primary biliary cirrhosis: towards a standard for clinical and trial use	2000
Denise Howel Dr Jane Metcalf Professor David Jones Emeritus Professor Oliver James	Cancer risk in primary biliary cirrhosis: A study in northern England	1999
Professor David Jones Emeritus Professor Oliver James Dr Michael Bramble	Case report: Oral antioxidant therapy for the treatment of primary biliary cirrhosis: A pilot study	1999
Dr Jeremy Palmer Professor David Jones Professor Janet Quinn Anna McHugh Emeritus Professor Steve Yeaman et al.	Characterization of the autoantibody responses to recombinant E3 binding protein (protein X) of pyruvate dehydrogenase in primary biliary cirrhosis	1999
Professor David Jones	Co-sensitisation with self- and homologous foreign-antigen as a mechanism of breakdown of self-tolerance in primary biliary cirrhosis (PBC)	1999
Dr Kaushik Agarwal Professor David Jones Professor Ann Daly Professor Margaret Bassendine	CTLA-4 gene polymorphism and chronicity in viral hepatitis	1999
Dr Kaushik Agarwal Professor David Jones Dr Peter Donaldson	CTLA-4 gene polymorphism and susceptibility to autoimmune hepatitis	1999
Dr Kaushik Agarwal Professor David Jones Professor Ann Daly Professor Margaret Bassendine Dr Mark Hudson et al.	CTLA-4 gene polymorphism and susceptibility to inflammatory bowel disease (IBD)	1999
Professor David Jones Emeritus Professor Oliver James Professor Alastair Burt Dr Mark Hudson	Development of autoimmune hepatitis following liver transplantation for primary biliary cirrhosis	1999
Professor David Jones Professor Margaret Bassendine Emeritus Professor Oliver James	Familial primary hiliary cirrhosis reassessed: A geographically-based population study	1999
Dr Kaushik Agarwal Professor David Jones Professor Margaret Bassendine	Genetic susceptibility to primary biliary cirrhosis [Review]	1999
Dr Jeremy Palmer Professor John Kirby Emeritus Professor Steve Yeaman Professor David Jones	Persistence of secretory autoantibodies in PBC patients post-liver transplant: a potential mechanism for disease recurrence?	1999
Dr Jeremy Palmer Emeritus Professor Steve Yeaman Professor Margaret Bassendine Professor David Jones	T cell responses to the putative dominant autoepitope in primary biliary cirrhosis (PBC)	1999
Dr Martin Prince Lorna Ingoe Professor David Jones Dr Irving Cobden Professor Roger Barton et al.	The CLO test in the UK: inappropriate reading and missed results	1999
Dr Kaushik Agarwal Professor David Jones	Treatment of hepatitis C infection - Review underplayed important public health issues	1999
Professor David Jones Professor Julia Newton Professor Ann Daly Professor Chris Day Emeritus Professor Oliver James et al.	Tumour necrosis factor-α promoter polymorphisms in primary biliary cirrhosis	1999
Professor David Jones Emeritus Professor Oliver James Professor Margaret Bassendine	Primary biliary cirrhosis: clinical and associated autoimmune features and natural history	1998