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Browsing publications by Professor Peter Blain.

Newcastle AuthorsTitleYearFull text
Professor Peter Blain
Chemical, biological, radiological, and nuclear mass casualty medicine: a review of lessons from the Salisbury and Amesbury Novichok nerve agent incidents2022
Dr Alistair Leitch
Dr Ibrahim Ibrahim
Dr Tarek Mamdouh Abdelghany
Dr Alex Charlton
Clair Roper
et al.
The methylimidazolium ionic liquid M8OI is detectable in human sera and is subject to biliary excretion in perfused human liver2021
Dr Tarek Mamdouh Abdelghany
Dr Alistair Leitch
Professor Peter Blain
Professor Matthew Wright
Changes in the gut microbiota of mice orally exposed to methylimidazolium ionic liquids2020
Professor Peter Blain
Chemical terrorism2020
Dr Michael Dunn
Dr Robert Jefferson
Professor Peter Blain
Professor Simon Thomas
Modest and variable efficacy of pre-exposure hydroxocobalamin and dicobalt edetate in a porcine model of acute cyanide salt poisoning2020
Dr Alistair Leitch
Dr Tarek Mamdouh Abdelghany
Dr Alex Charlton
Professor Fiona Oakley
Dr Lee Borthwick
et al.
Renal injury and hepatic effects from the methylimidazolium ionic liquid M8OI in mouse2020
Dr Alistair Leitch
Dr Tarek Mamdouh Abdelghany
Dr Phillip Probert
Dr Stephanie Meyer
Dr Jeremy Palmer
et al.
The toxicity of the methylimidazolium ionic liquids, with a focus on M8OI and hepatic effects2020
Professor Peter Blain
Threat potential of pharmaceutical based agents2020
Dr Stephanie Meyer
Dr Michael Dunn
Dr Daniel Vidler
Professor Peter Blain
Dr Paul Jowsey
et al.
Phosphorylation of MCPH1 isoforms during mitosis followed by isoform-specific degradation by APC/C-CDH12019
Dr Paul Keane
Dr Peter Hanson
Lina Patterson
Professor Peter Blain
Philippa Hepplewhite
et al.
Trichloroethylene and its metabolite TaClo lead to degeneration of substantia nigra dopaminergic neurones: Effects in wild type and human A30P mutant α-synuclein mice 2019
Dr Shahriar Khateri
Professor Mahdi Balali-Mood
Professor Peter Blain
Emeritus Professor Faith Williams
Dr Paul Jowsey
et al.
DNA damage and repair proteins in cellular response to sulfur mustard in Iranian veterans more than two decades after exposure2018
Dr Ann Fitchett
Professor Peter Blain
Dr Christopher Morris
Dr Sarah Judge
Gene expression analysis reveals chronic low level exposure to the pesticide diazinon affects Psychological Disorders gene sets in the adult rat2018
Dr Phillip Probert
Dr Alistair Leitch
Dr Michael Dunn
Dr Stephanie Meyer
Dr Jeremy Palmer
et al.
Identification of a xenobiotic as a potential environmental trigger in primary biliary cholangitis2018
Rizwan Nisar
Dr Peter Hanson
Dr Paul Keane
Dr Langping He
Professor Robert Taylor
et al.
Manganese-Containing Thiocarbamates Cause Free Radical Production and Caspase-Independent Cell Death following Mitochondrial Dysfunction in Neural Cells2018
Professor Peter Blain
Dr Paul Jowsey
Dr Shahriar Khateri
Professor Mahdi Balali-Mood
Telomere shortening associated with increased levels of oxidative stress in sulfur mustard-exposed Iranian veterans2018
Dr Alistair Leitch
Anne Lakey
will Hotham
Professor Loranne Agius
Professor George Kass
et al.
The ionic liquid 1-octyl-3-methylimidazolium (M8OI) is an activator of the human estrogen receptor alpha2018
Dr Stephanie Meyer
Dr Phillip Probert
Anne Lakey
Dr Alistair Leitch
Dr Lynsay Blake
et al.
Environmental xenoestrogens super-activate a variant murine ER beta in cholangiocytes2017
Dr Stephanie Meyer
Dr Phillip Probert
Anne Lakey
Andrew Axon
Dr Alistair Leitch
et al.
Hepatic effects of tartrazine (E 102) after systemic exposure are independent of oestrogen receptor interactions in the mouse2017
Dr Ahmad Khundakar
Dr Peter Hanson
Dr Daniel Erskine
Dr Nichola Lax
Evangelia Karyka
et al.
Analysis of primary visual cortex in dementia with Lewy bodies indicates GABAergic involvement associated with recurrent complex visual hallucinations2016
Dr Simon Hill
Dr Michael Dunn
Professor Peter Blain
Professor Simon Thomas
Clinical toxicity following analytically confirmed use of the synthetic cannabinoid receptor agonist MDMB-CHMICA. A report from the Identification Of Novel psychoActive substances (IONA) study2016
Professor Peter Blain
Dr Paul Jowsey
Fe65 is Phosphorylated on Ser289 after UV-Induced DNA Damage2016
Dr Sarah Judge
Claire Savy
Dr Madeline Campbell
Rebecca Dodds
Grace Laws
et al.
Mechanism for the acute effects of organophosphate pesticides on the adult 5-HT system2016
Dr Peter Hanson
Professor Peter Blain
Dr Christopher Morris
Neurotoxicity of novel psychoactive substances2016
Dr Phillip Probert
Dr Stephanie Meyer
Fouzeyyah Alsaeedi
Andrew Axon
Dr Emma Fairhall
et al.
An expandable donor-free supply of functional hepatocytes for toxicology2015
Dr Paul Jowsey
Professor Peter Blain
Checkpoint kinase 1 is activated and promotes cell survival after exposure to sulphur mustard2015
Rizwan Nisar
Dr Peter Hanson
Dr Langping He
Professor Robert Taylor
Professor Peter Blain
et al.
Diquat causes caspase-independent cell death in SH-SY5Y cells by production of ROS independently of mitochondria2015
Claire Savy
Dr Ann Fitchett
Dr Richard McQuade
Dr Sasha Gartside
Dr Christopher Morris
et al.
Low-level repeated exposure to diazinon and chlorpyrifos decrease anxiety-like behaviour in adult male rats as assessed by marble burying behaviour2015
Professor Peter Blain
Mass casualty decontamination in a chemical or radiological/nuclear incident with external contamination: Guiding principles and research needs2015
Dr Simon Hill
Professor Simon Thomas
Emeritus Professor Paul Flecknell
Dr Aurelie Thomas
Dr Christopher Morris
et al.
Rapid and equivalent systemic bioavailability of the antidotes HI-6 and dicobalt edetate via the intraosseous and intravenous routes2015
Aimen Amer
Dr Phillip Probert
Dr Michael Dunn
Margaret Knight
Dr Abigail Vallance
et al.
Sustained Isoprostane E2 Elevation, Inflammation and Fibrosis after Acute Ischaemia-Reperfusion Injury Are Reduced by Pregnane X Receptor Activation2015
Dr Christopher Morris
Claire Savy
Dr Sarah Judge
Professor Peter Blain
Acute toxicity of organophosphorus compounds2014
Dr Paul Jowsey
Professor Peter Blain
Fe65 Ser228 is Phosphorylated by ATM/ATR and Inhibits Fe65-APP-Mediated Gene Transcription2014
Dr John Skamarauskas
Professor Fiona Oakley
Dr Fiona Smith
Carlo Bawn
Dr Michael Dunn
et al.
Non-invasive in vivo magnetic resonance measures of glutathione synthesis in human and rat liver as an oxidative stress biomarker2014
Craig Moore
Dr Simon Wilkinson
Professor Peter Blain
Dr Michael Dunn
Dr Gillian Aust
et al.
Percutaneous absorption and distribution of organophosphates (chlorpyrifos and dichlorvos) following dermal exposure and decontamination scenarios using in vitro human skin model2014
Dr Stephanie Meyer
Andrew Axon
Dr Paul Jowsey
Emeritus Professor Faith Williams
Professor Peter Blain
et al.
Tartrazine is not an activator of the mouse oestrogen ER alpha and ER beta receptors2014
Dr Simon Wilkinson
Professor Peter Blain
Professor Faith Williams
Use of a human skin in vitro model to investigate the influence of 'every-day' clothing and skin surface decontamination on the percutaneous penetration of organophosphates2014
Dr Paul Jowsey
Professor Peter Blain
Whole Genome Expression Analysis in Primary Bronchial Epithelial Cells after Exposure to Sulphur Mustard2014
Professor Peter Blain
A screening tool to prioritize public health risk associated with accidental or deliberate release of chemicals into the atmosphere2013
Raghu Sidaginamale
Professor Tom Joyce
James Lord
Dr Robert Jefferson
Professor Peter Blain
et al.
Blood metal ion testing is an effective screening tool to identify poorly performing metal on metal bearing surfaces2013
Dr Shahriar Khateri
Dr Paul Jowsey
Professor Peter Blain
Professor Mahdi Balali-Mood
Deoxyribonucleic acid damage in Iranian veterans 25 years after wartime exposure to sulfur mustard2013
Dr Simon Hill
Dr Michael Dunn
Professor Peter Blain
Professor Simon Thomas
Severe clinical toxicity associated with analytically confirmed recreational use of 25I–NBOMe: case series2013
Andrew Baron
Professor Stephen Rushton
Dr Christopher Morris
Professor Peter Blain
Dr Sarah Judge
et al.
Sex differences in effects of low level domoic acid exposure2013
Professor Tom Joyce
Professor Peter Blain
Dr Robert Jefferson
The clinical implications of elevated blood metal ion concentrations in asymptomatic patients with MoM hip resurfacings: a cohort study2013
Professor Peter Blain
Biotoxins and Bioterrorism: Ricin and Saxitoxin2012
Dr Peter Hanson
Professor Peter Blain
Dr Christopher Morris
Brominated flame retardants - Neurotoxic to humans?2012
Dr Paul Jowsey
Professor Faith Williams
Professor Peter Blain
DNA damage responses in cells exposed to sulphur mustard2012
Dr Marzena Kurzawa-Akanbi
Dr Peter Hanson
Professor Peter Blain
Debbie Lett
Professor Ian McKeith
et al.
Glucocerebrosidase Mutations alter the endoplasmic reticulum and lysosomes in Lewy body disease2012
Professor Simon Thomas
Dr Robert Jefferson
Dr Michael Dunn
Dr Daniel Vidler
Professor Peter Blain
et al.
Rapid and complete bioavailability of antidotes for organophosphorus nerve agent and cyanide poisoning in minipigs after intraosseous administration2012
Andrew Axon
Dr Felicity May
Dr Luke Gaughan
Professor Faith Williams
Professor Peter Blain
et al.
Tartrazine and sunset yellow are xenoestrogens in a new screening assay to identify modulators of human oestrogen receptor transcriptional activity2012
Paul Keane
Dr Sarah Judge
Professor Peter Blain
Dr Christopher Morris
An investigation into the mechanism of trichloroethylene neurotoxicity in relation to Parkinsonism2011
Claire Savy
Dr Christopher Morris
Professor Peter Blain
Dr Sarah Judge
Behavioural effects of low level exposure to organophosphate pesticides2011
Paul Keane
Dr Marzena Kurzawa-Akanbi
Professor Peter Blain
Dr Christopher Morris
Mitochondrial dysfunction in Parkinson's Disease2011
Andrew Baron
Rachel Steeg
Dr Christopher Morris
Professor Peter Blain
Dr Sarah Judge
et al.
Motor activity is a sensitive behavioural biomarker of low level exposure to the shellfish toxin, domoic acid, in male and female rats2011
Dr Paul Jowsey
Professor Faith Williams
Professor Peter Blain
The role of homologous recombination in the cellular response to sulphur mustard2011
Andy Axon
Dr David Cowie
Professor Fiona Oakley
Professor Faith Williams
Professor Peter Blain
et al.
Acute oestradiol (E2) administration to mice results in liver portal tract inflammation2010
Professor Peter Blain
Dr Robert Jefferson
Occupational Toxicology: general principles2010
Dr Paul Jowsey
Professor Faith Williams
Professor Peter Blain
The role of homologous recombination in the cellular response to sulphur mustard2010
Dr Robert Jefferson
Professor Peter Blain
Professor Simon Thomas
Diagnosis and treatment of polonium poisoning Polonium poisoning2009
Professor Peter Blain
Dr Robert Jefferson
Professor Simon Thomas
Did he really bring the war home with him?2009
Dr Kathryn Atherton
Professor Faith Williams
Professor Stephen Rushton
Professor Peter Blain
Dr Elaine Mutch
et al.
DNA damage in horticultural farmers: a pilot study showing an association with organophosphate pesticide exposure2009
Dr Paul Jowsey
Professor Faith Williams
Professor Peter Blain
DNA damage, signalling and repair after exposure of cells to the sulphur mustard analogue 2-chloroethyl ethyl sulphide2009
Seth Remington
Dr Paul Jowsey
Professor Faith Williams
Professor Peter Blain
Investigations into the genotoxic potential of dichlorvos2008
Dr Elaine Mutch
Professor Peter Blain
Professor Faith Williams
A possible mechanism for the neurotoxicity of trichloroethylene to man2007
Ria Wilkinson
Dr Christopher Jewell
Dr Simon Wilkinson
Professor Faith Williams
Professor Peter Blain
et al.
The effect of in vitro receptor media choice on the percutaneous absorption of methyl paraben2007
Professor Peter Blain
Clinical management of casualties exposed to lung damaging agents: a critical review2006
Zhen Jiang
Dr Elaine Mutch
Professor Peter Blain
Professor Faith Williams
Conversion of trichloroethylene to chloral using occupationally relevant levels2006
Professor Peter Blain
Supplement to HOSDB Evaluations of Taser Devices: A collection of medical evidence and other source material2006
Dr Ovnair Sepai Adem BEM
Professor Faith Williams
David Henderson
Professor Peter Blain
Biological monitoring of exposure to organochlorine pesticides in an African population2005
Vanessa Gage
Professor Peter Blain
Julian Leathart
Professor Ann Daly
Professor Faith Williams
et al.
Association of DNA damage to human peripheral lymphocytes with age and MnSOD and OGG1 genotype2004
Vanessa Gage
Professor Peter Blain
Dr Elaine Mutch
Professor Faith Williams
DNA damage and 8-hydroxy-2 '-deoxyguanosine formation due to hydrogen peroxide exposure in HepG2 cells2004
Professor Peter Blain
Guidance on a strategy for the risk assessment of chemical carcinogens2004
Emeritus Professor John Harris
Professor Peter Blain
Neurotoxicology: What the neurologist needs to know2004
Emeritus Professor John Harris
Professor Peter Blain
Neurotoxicology: What the neurologist needs to know2004
Professor Peter Blain
Report of a Royal Society Group: Making the UK safer: detecting and decontaminating chemical and biological agents2004
Professor Peter Blain
Committee on carcinogenicity of chemicals in food, consumer products and the environment - Statement on ILSI/HESI research programme on alternative cancer models.2003
Dr Elaine Mutch
Professor Ann Daly
Julian Leathart
Professor Peter Blain
Professor Faith Williams
et al.
Do multiple cytochrome P450 isoforms contribute to parathion metabolism in man?2003
Professor Peter Blain
Tear gases and irritant incapacitants: 1-Chloroacetophene, 2-Chlorobenzylidene malononitrile and dibenz[B,F]-1,4-oxazepine2003
Professor Peter Blain
Treatment of poisoning by selected chemical compounds2003
Professor Tanja Pless-Mulloli
Professor Peter Blain
Environmental Hazards and Health: A Scoping Study2002
Professor Peter Blain
Adverse health effects after low level exposure to organophosphates2001
Professor Peter Blain
Assessing “Sun Know How”: comparing outdoor and indoor workers.2001
Professor Peter Blain
Genomics: Some Implications for Defence2001
Professor Peter Blain
The Role of the Defence Scientific Advisory Council2001
Denise Howel
Professor Stephen O'Brien
Dr David Chinn
Professor Peter Blain
Upper aerodigestive tract cancers in former employees at an iron and steel works2001
Dr Elaine Mutch
Professor Faith Williams
Professor Peter Blain
Cytogenetic response without changes in peripheral cholinesterase enzymes following exposure to a sheep dip containing diazinon in vivo and in vitro2000
Dr Gail De Blaquiere
Louise Waters
Professor Peter Blain
Professor Faith Williams
Electrophysiological and biochemical effects of single and multiple doses of the organophosphate diazinon in the mouse2000
Professor Peter Blain
The Environmental Aspects of Dialysis2000
Dr Elaine Mutch
Professor Peter Blain
Professor Faith Williams
The role of metabolism in determining susceptibility to parathion toxicity in man1999
Professor Peter Blain
Occupational asthma due to porcine pancreatic amylase1998
Professor Peter Blain
Professor Faith Williams
The percutaneous absorption and skin distribution of lindane in man. II. In vitro studies1997
Professor Peter Blain
Professor Faith Williams
The effect of sulphur mustard on glutathione levels in rat lung slices and the influence of treatment with arylthiols and cysteine esters1996
Dr Elaine Mutch
Professor Peter Blain
Professor Faith Williams
Interindividual variations in enzymes controlling organophosphate toxicity in man1992