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Browsing publications by Professor Tim Goodship.

Newcastle AuthorsTitleYearFull text
Professor Kevin Marchbank
Dr Isabel Pappworth
Harriet Denton
Kate Cooke
Grant Richardson
et al.
C3 Glomerulopathy and Related Disorders in Children.2021
Dr Suren Kanagasundaram
Dr Simon Baudouin
Sarah Rowling
Professor John Dark
Professor Tim Goodship
et al.
Mitochondrial Haplogroup and the Risk of Acute Kidney Injury Following Cardiac Bypass Surgery2019
Dr Rebecca Darlay
Aisling Stewart
Dr Yaobo Xu
Dr Heather Lambert
Dr Mauro Santibanez Koref
et al.
Erratum: Publisher Correction: Genome-wide linkage and association study implicates the 10q26 region as a major genetic contributor to primary nonsyndromic vesicoureteric reflux (Scientific reports (2017) 7 1 (14595))2018
Professor David Kavanagh
Dr Valerie Wilson
Professor Tim Goodship
Statistical Validation of Rare Complement Variants Provides Insights into the Molecular Basis of Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy2018
Professor Tim Goodship
Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference2017
Dr Vicky Brocklebank
Dr Sally Johnson
Dr Patrick Walsh
Dr Edwin Wong
Dr Larissa Kerecuk
et al.
Factor H autoantibody is associated with atypical hemolytic uremic syndrome in children in the United Kingdom and Ireland2017
Dr Rebecca Darlay
Aisling Stewart
Dr Yaobo Xu
Dr Mauro Santibanez Koref
Professor John Sayer
et al.
Genome-wide linkage and association study implicates the 10q26 region as a major genetic contributor to primary nonsyndromic vesicoureteric reflux2017
Rachel Challis
Dr Edwin Wong
Dr Vicky Brocklebank
Dr Valerie Wilson
Professor Kevin Marchbank
et al.
Thrombotic Microangiopathy in Inverted Formin 2-Mediated Renal Disease2017
Rachel Challis
Dr Edwin Wong
Dr Holly Anderson
Dr Valerie Wilson
Dr Vicky Brocklebank
et al.
A De Novo Deletion in the Regulators of Complement Activation Cluster Producing a Hybrid Complement Factor H/Complement Factor H–Related 3 Gene in Atypical Hemolytic Uremic Syndrome2016
Professor Neil Sheerin
Professor David Kavanagh
Professor Tim Goodship
Dr Sally Johnson
A national specialised service in England for atypical haemolytic uraemic syndrome – the first year’s experience2016
Professor Tim Goodship
An unusual case of haemolytic uraemic syndrome following endoscopic retrograde cholangiopancreatography rapidly improved with eculizumab2016
Dr Valerie Wilson
Tom Cox
Dr Kate Smith-Jackson
Professor David Kavanagh
Professor Tim Goodship
et al.
Chromosomal rearrangement – a rare cause of complement factor I associated atypical haemolytic uraemic syndrome2016
Dr Veronique Fremaux-Bacchi
Professor Tim Goodship
Database of Complement Gene Variants: A comprehensive database providing insights on function, structure and allele frequency for genetic variants identified in complement-mediated diseases2016
Professor Tim Goodship
Professor Neil Sheerin
Management of Recurrent aHUS After Adult Kidney transplantation Despite Eculizumab Prophylaxis.2016
Professor Tim Goodship
Prevention of recurrence of atypical hemolytic uremic syndrome post renal transplant with the use of higher-dose eculizumab2016
Dr Vicky Brocklebank
Dr Edwin Wong
Professor Kevin Marchbank
Professor Tim Goodship
Professor David Kavanagh
et al.
The role of ADAMTS-13 activity and complement mutational analysis in differentiating acute thrombotic microangiopathies2016
Dr Veronique Fremaux-Bacchi
Professor Tim Goodship
Professor David Kavanagh
Atypical aHUS: State of the art2015
Rachael Horbury
Dr Karim Bennaceur
Catriona Barker
Professor David Kavanagh
Professor Tim Goodship
et al.
Autoantibodies to CD59, CD55, CD46 or CD35 are not associated with atypical haemolytic uraemic syndrome (aHUS)2015
Professor Tim Goodship
Case Report: Benefits and Challenges of Long-term Eculizumab in Atypical Hemolytic Uremic Syndrome2015
Dr Edwin Wong
Dr Vicky Brocklebank
Professor Tim Goodship
Professor David Kavanagh
Dr Anna Richards
et al.
Characterisation of a C3 Mutation with Increased Resistance to Complement Regulation in an Individual with Recurrent C3GN in a Renel Transplant2015
Professor Tim Goodship
Professor Neil Sheerin
Efficacy and safety of eculizumab in atypical hemolytic uremic syndrome from 2-year extensions of phase 2 studies2015
Dr Valerie Wilson
Professor Tim Goodship
Dr Veronique Fremaux-Bacchi
Mapping interactions between complement C3 and regulators using mutations in atypical hemolytic uremic syndrome2015
Professor Judith Goodship
Professor Tim Goodship
Mutations in TBX18 Cause Dominant Urinary Tract Malformations via Transcriptional Dysregulation of Ureter Development2015
Dr Edwin Wong
Rachel Challis
Professor Neil Sheerin
Dr Sally Johnson
Professor David Kavanagh
et al.
Patient stratification and therapy in atypical haemolytic uraemic syndrome (aHUS)2015
Dr Mustafa Sevinc
Dr Vicky Brocklebank
Professor Tim Goodship
Professor David Kavanagh
Plasma resistant atypical hemolytic uremic syndrome associated with a CFH mutation treated with eculizumab: A case report2015
Dr Edwin Wong
Dr Isabel Pappworth
Professor Claire Harris
Professor Tim Goodship
Dr Sally Johnson
et al.
The national study of membranoproliferative glomerulonephrtis and C3 glomerulopathy - characterisation of the paediatric cohort2015
Professor Tim Goodship
Dr Sally Johnson
Dr Veronique Fremaux-Bacchi
The role of complement in C3 glomerulopathy2015
Professor Tim Goodship
Dr Alison Brown
Professor Neil Sheerin
Thrombotic microangiopathy as a cause of chronic kidney transplant dysfunction: a case report demonstrating successful treatment with Eculizumab2015
Professor Judith Goodship
Professor Tim Goodship
Dr Heather Lambert
Professor Heather Cordell
Urinary Tract Effects of HPSE2 Mutations2015
Professor Tim Goodship
Use of eculizumab in crescentic IgA nephropathy: Proof of principle and conundrum?2015
Professor Tim Goodship
Professor Kevin Marchbank
A novel method for direct measurement of complement convertases activity in human serum2014
Professor Tim Goodship
Professor Kevin Marchbank
A novel method for direct measurement of complement convertases activity in human serum2014
Dr Vicky Brocklebank
Dr Edwin Wong
Professor Tim Goodship
Professor David Kavanagh
Atypical haemolytic uraemic syndrome associated with a CD46 mutation triggered by Shigella flexneri2014
Catriona Barker
Professor David Kavanagh
Professor Tim Goodship
Dr Isabel Pappworth
Autoantibodies to CD59, CD55, CD46 and CD35 are not associated with aHUS2014
Dr Edwin Wong
Dr Holly Anderson
Rachel Challis
Dr Lisa Turnbull
Gladys -
et al.
Characterization of a Factor H Mutation That Perturbs the Alternative Pathway of Complement in a Family with Membranoproliferative GN2014
Professor Tim Goodship
Complement factor H-related hybrid protein deregulates complement in dense deposit disease2014
Professor Heather Cordell
Dr Valerie Wilson
Professor Judith Goodship
Professor Tim Goodship
Factors determining penetrance in familial atypical haemolytic uraemic syndrome2014
Professor Tim Goodship
How I treat thrombotic thrombocytopenic purpura and atypical haemolytic uraemic syndrome2014
Professor Tim Goodship
Time to Improvements with Eculizumab in Patients with Atypical Haemolytic Uraemic Syndrome of Long Duration and Chronic Kidney Disease: 3-Year Update2014
Dr Lisa Turnbull
Professor Tim Goodship
Dr Veronique Fremaux-Bacchi
A prevalent CFHR1/FH reverse hybrid gene in aHUS patients induces deregulation of the alternative pathway2013
Rachel Challis
Dr Holly Anderson
Dr Edwin Wong
Dr Lisa Turnbull
Professor Kevin Marchbank
et al.
Atypical haemolytic uraemic syndrome associated with a novel hybrid CFH/CFHR3 gene2013
Professor David Kavanagh
Professor Tim Goodship
Dr Anna Richards
Atypical hemolytic uremic syndrome2013
Professor Tim Goodship
Changing strategies for organ transplantation in atypical haemolytic uraemic syndrome: A tertiary case series2013
Dr Veronique Fremaux-Bacchi
Professor Tim Goodship
Combined Complement Gene Mutations in Atypical Hemolytic Uremic Syndrome Influence Clinical Phenotype2013
Professor Tim Goodship
Complement deregulation in dense deposit disease by a novel CFHR2-CFHR5 hybrid protein2013
Dr Edwin Wong
Professor Tim Goodship
Professor David Kavanagh
Complement therapy in atypical haemolytic uraemic syndrome (aHUS)2013
Dr Lucy Holmes
Dr Lisa Turnbull
Dr Iain Moore
Professor Kevin Marchbank
Professor David Kavanagh
et al.
Determining the Population Frequency of the CFHR3/CFHR1 Deletion at 1q322013
Professor Tim Goodship
Distribution and determinants of circulating complement factor H concentration determined by a high-throughput immunonephelometric assay2013
Professor Tim Goodship
Eculizumab in aHUS pts with long disease duration, with or without renal transplant2013
Dr Steven Hardy
Professor Tim Goodship
Eculizumab therapy for atypical haemolytic uraemic syndrome due to a gain-of-function mutation of complement factor B2013
Professor Tim Goodship
Efficacy and safety of Eculizumab in the treatment of atypical haemolyticuraemic syndrome: A single tertiary centre experience2013
Professor Tim Goodship
Professor Neil Sheerin
Efficacy of Eculizumab in atypical hemolytic uremic syndrome (aHUS) patients with or without prior transplant2013
Dr Valerie Wilson
Dr Rebecca Darlay
Dr Katrina Wood
Professor Claire Harris
Dr Eva-Maria Hunze
et al.
Genotype/Phenotype Correlations in Complement Factor H Deficiency Arising From Uniparental Isodisomy2013
Professor Tim Goodship
Long-term efficacy of Eculizumab in patients with atypical haemolyticuraemic syndrome with a long disease duration and chronic kidney disease2013
Professor Neil Sheerin
Professor Tim Goodship
Terminal Complement Inhibitor Eculizumab in Atypical Hemolytic–Uremic Syndrome2013
Professor Tim Goodship
Use of Eculizumab in atypical haemolyticuraemic syndrome associated with complement factor B variant2013
Professor David Kavanagh
Dr Lisa Turnbull
Professor Kevin Marchbank
Professor Claire Harris
Professor Tim Goodship
et al.
A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome2012
Dr Luca Ermini
Professor Tim Goodship
Dr Lisa Turnbull
Professor Heather Cordell
Dr Veronique Fremaux-Bacchi
et al.
Common genetic variants in complement genes other than CFH, CD46 and the CFHRs are not associated with aHUS.2012
Dr Luca Ermini
Dr Ian Wilson
Professor Tim Goodship
Professor Neil Sheerin
Complement polymorphisms: Geographical distribution and relevance to disease2012
Dr Lisa Turnbull
Professor Tim Goodship
Dense deposits disease (DDD): Favorable long-term outcome on enalapril despite persistence of complement activation2012
Professor Tim Goodship
Eculizumab (ECU) Safety and Efficacy in Atypical Hemolytic Uremic Syndrome (aHUS) Patients with Long Disease Duration and Chronic Kidney Disease (CKD): 2-Year Results2012
Professor Tim Goodship
Eculizumab Is an Effective Treatment for Atypical Hemolytic Uremic Syndrome in Patients with or without Identified Genetic Complement Mutations or Complement Factor H Auto-Antibodies2012
Professor Tim Goodship
Dr Isabel Pappworth
Dr Iain Moore
Dr Eva-Maria Hunze
James Staniforth
et al.
Factor H autoantibodies in membranoproliferative glomerulonephritis2012
Professor David Kavanagh
Dr Isabel Pappworth
Christine Hayes
Dr Iain Moore
Dr Eva-Maria Hunze
et al.
Factor I Autoantibodies in Patients with Atypical Hemolytic Uremic Syndrome: Disease-Associated or an Epiphenomenon?2012
Dr Edwin Wong
Dr Holly Anderson
Rachel Challis
Professor Kevin Marchbank
Professor David Kavanagh
et al.
Familial membranoproliferative glomerulonephritis type I associated with a functionally significant mutation in complement factor H2012
Dr Karim Bennaceur
Dr Eva-Maria Hunze
James Staniforth
Dr Lisa Turnbull
Dr Valerie Wilson
et al.
MCP (CD46) autoantibodies are associated with atypical hemolytic uremic syndrome2012
Dr Valerie Wilson
Dr Iain Moore
Dr Lisa Turnbull
Professor Kevin Marchbank
Professor Neil Sheerin
et al.
Postpartum aHUS Secondary to a Genetic Abnormality in Factor H Acquired Through Liver Transplantation2012
Professor Tim Goodship
Professor Claire Harris
Sensitive and specific assays for C3 nephritic factors clarify mechanisms underlying complement dysregulation2012
Dr Lisa Turnbull
Professor Tim Goodship
The European MPGN Registry: Novel genetic- and autoimmune-factors allow a differentiation between MPGN subtype I and subtype II2012
Professor Tim Goodship
Association of Genetic Variants in Complement Factor H and Factor H-Related Genes with Systemic Lupus Erythematosus Susceptibility2011
Professor Tim Goodship
Eculizumab Is An Effective Long-Term Treatment In Patients with Atypical Hemolytic Uremic Syndrome (aHUS) Previously Receiving Chronic Plasma Exchange/Infusion (PE/PI): Extension Study Results2011
Professor Tim Goodship
Eculizumab is an effective treatment for patients with atypical hemolytic syndrome (aHUS) receiving chronic plasma therapy (PT)2011
Dr Luca Ermini
Professor Tim Goodship
Dr Lisa Turnbull
Professor Heather Cordell
Dr Veronique Fremaux-Bacchi
et al.
Genetic variants in CFH and CD46 are the major susceptibility factors for aHUS-An association study of multiple complement genes2011
Professor David Kavanagh
Professor Tim Goodship
Haemolytic Uraemic Syndrome2011
Dr Roslyn Simms
Professor John Sayer
Dr Richard Quinton
Professor Mark Walker
Professor Tim Goodship
et al.
Monogenic diabetes, renal dysplasia and hypopituitarism: a patient with a HNF1A mutation2011
Professor David Kavanagh
Professor Tim Goodship
Dr Veronique Fremaux-Bacchi
Mutations in Complement Regulatory Proteins Predispose to Preeclampsia: A Genetic Analysis of the PROMISSE Cohort2011
Professor Tim Goodship
Plasma therapy for atypical haemolytic uraemic syndrome associated with heterozygous factor H mutations2011
Professor Tim Goodship
Prevention of large-vessel stenoses in atypical hemolytic uremic syndrome associated with complement dysregulation2011
Aisling Stewart
Professor Heather Cordell
Professor Judith Goodship
Professor Tim Goodship
Primary, Nonsyndromic Vesicoureteric Reflux and Nephropathy in Sibling Pairs: A United Kingdom Cohort for a DNA Bank2011
Dr Colin Wilson
Dr Nicholas Torpey
Bryon Jaques
Dr Lisa Turnbull
David Talbot
et al.
Successful Simultaneous Liver-Kidney Transplant in an Adult With Atypical Hemolytic Uremic Syndrome Associated With a Mutation in Complement Factor H2011
Dr Alison Brown
Professor Tim Goodship
Professor Neil Sheerin
Professor Derek Manas
Successful Treatment of De Novo Posttransplant Thrombotic Microangiopathy With Eculizumab2011
Professor David Kavanagh
Dr Lisa Turnbull
Professor Kevin Marchbank
Professor Tim Goodship
A novel hybrid complement gene associated with familial haemolytic uraemic syndrome2010
Dr Iain Moore
Dr Lisa Turnbull
Dr Isabel Pappworth
Professor David Kavanagh
James Staniforth
et al.
Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome2010
Professor Heather Cordell
Professor Tim Goodship
Associations of CFHR1-CFHR3 deletion and a CFH snp to age-related macular degeneration are not independent reply2010
Dr Lisa Turnbull
Professor Tim Goodship
Atypical haemolytic uraemic syndrome in one large kindred predisposed by factor H mutation penetrance data based on mutation testing and family history2010
Professor David Kavanagh
Professor Tim Goodship
Atypical hemolytic uremic syndrome2010
Professor Tim Goodship
Clinical Practice Guidelines for the management of atypical Haemolytic Uraemic Syndrome in the United Kingdom2010
Dr Isabel Pappworth
Dr Iain Moore
Dr Lisa Turnbull
Professor David Kavanagh
James Staniforth
et al.
Complement Factor H Autoantibodies and Age-Related Macular Degeneration2010
Professor Tim Goodship
Early Intensive Plasma Exchange (PEX) for Atypical Haemolytic Uraemic Syndrome (aHUS) May Slow Progression to End-Stage Renal Failure (ESRF) [meeting abstract]2010
Professor David Kavanagh
Dr Isabel Pappworth
Dr John Tapson
Dr Iain Moore
Dr Lisa Turnbull
et al.
Factor I autoantibodies are associated with atypical haemolytic uraemic syndrome2010
Professor David Kavanagh
Dr Lisa Turnbull
Professor Kevin Marchbank
Professor Tim Goodship
Functional characterisation of a novel hybrid complement factor H protein associated with atypical haemolytic uraemic2010
Professor David Kavanagh
Professor Tim Goodship
Genetics and complement in atypical HUS2010
Professor Kevin Marchbank
Professor Tim Goodship
Impact of compound heterozygous complement factor H mutations on development of atypical hemolytic uremic syndrome-A pedigree revisited2010
Dr Lisa Turnbull
Professor Tim Goodship
Maintenance of Kidney Function Following Treatment With Eculizumab and Discontinuation of Plasma Exchange After a Third Kidney Transplant for Atypical Hemolytic Uremic Syndrome Associated With a CFH Mutation2010
Professor David Kavanagh
Professor Tim Goodship
Dr Veronique Fremaux-Bacchi
Mutations in complement regulatory proteins predispose to preeclampsia2010
Professor Tim Goodship
Non-atheromatous arterial stenoses in atypical haemolytic uraemic syndrome associated with complement dysregulation2010
Professor Tim Goodship
Professor David Kavanagh
Pulling the Trigger in Atypical Hemolytic Uremic Syndrome: The Role of Pregnancy2010
Professor Tim Goodship
Relative Role of Genetic Complement Abnormalities in Sporadic and Familial aHUS and Their Impact on Clinical Phenotype2010
Professor Heather Cordell
Professor Tim Goodship
Reply to “Associations of CFHR1–CFHR3 deletion and a CFH SNP to age-related macular degeneration are not independent”2010
Professor Tim Goodship
Successful Isolated Liver Transplantation in a Child with Atypical Hemolytic Uremic Syndrome and a Mutation in Complement Factor H2010
Dr Isabel Pappworth
Professor Kevin Marchbank
Dr Lisa Turnbull
Professor Tim Goodship
Successful Renal Transplantation in Factor H Autoantibody Associated HUS with CFHR1 and 3 Deficiency and CFH Variant G2850T2010
Professor David Kavanagh
Professor Tim Goodship
Transplantation in Atypical Hemolytic Uremic Syndrome2010
Professor Kevin Marchbank
Professor David Kavanagh
Dr Lisa Turnbull
Professor Tim Goodship
Triggering of atypical hemolytic uremic syndrome by influenza A (H1N1)2010
Professor Heather Cordell
Dr Rebecca Darlay
Dr Heather Lambert
Professor Tim Goodship
Dr Rajko Kenda
et al.
Whole-Genome Linkage and Association Scan in Primary, Nonsyndromic Vesicoureteric Reflux2010
Dr Lisa Turnbull
Professor Tim Goodship
Eculizumab allows plasma exchange iscontinuation after a third kidney transplantation in a patient with plasma dependent atypical HUS due to CFH mutation2009
Dr Lisa Turnbull
Professor Tim Goodship
Eculizumab allows plasma exchnage discontinuation after a third kidney transplantation in a patient with plasma dependent atypical hus due to CFH mutation2009
Professor Kevin Marchbank
Dr Lisa Turnbull
Dr Veronique Fremaux-Bacchi
James Staniforth
Professor David Kavanagh
et al.
Genomic disorders associated with aHUS2009
Dr Lisa Turnbull
Professor Tim Goodship
In atypical HUS (aHUS), the EKZ-AMC protocol of plasma therapy (PT) prevents a chronic renal failure, allows successful kidney transplantation and avoid cerebral arteries stenosis2009
Dr Matthew Edey
Dr Lisa Turnbull
Professor Tim Goodship
Is complement factor H a susceptibility factor for IgA nephropathy?2009
Dr Veronique Fremaux-Bacchi
Professor Tim Goodship
Liver-kidney transplantation to cure atypical hemolytic uremic syndrome2009
Dr Lisa Turnbull
Professor Tim Goodship
Prophylactic plasma exchange in CD46-associated atypical haemolytic uremic syndrome2009
James Staniforth
Professor David Kavanagh
Dr Lisa Turnbull
Professor Tim Goodship
Professor Kevin Marchbank
et al.
Towards a highly specific Factor H ELISA for rapid screening of patient sera2009
Professor Tim Goodship
Uromodulin mutations causing familial juvenile hyperuricaemic nephropathy lead to protein maturation defects and retention in the endoplasmic reticulum2009
Dr Matthew Edey
Professor David Kavanagh
Dr Anne Lampe
Professor Judith Goodship
Dr Lisa Turnbull
et al.
A Novel Non-Synonymous Polymorphism (p.Arg240His) in C4b-Binding Protein Is Associated with Atypical Hemolytic Uremic Syndrome and Leads to Impaired Alternative Pathway Cofactor Activity2008
Dr Iain Moore
Dr Lisa Turnbull
Professor Tim Goodship
Professor Kevin Marchbank
Anti-factor H autoantibodies in aHUS - Is there an association with CFHR1/3 copy number?2008
Dr Matthew Edey
Dr Lisa Turnbull
Professor Tim Goodship
Dr Suren Kanagasundaram
Association of a Factor H Mutation With Hemolytic Uremic Syndrome Following a Diarrheal Illness2008
Professor Tim Goodship
Chapter 14 Hemolytic Uremic Syndrome/Thrombotic Thrombocytopenic Purpura2008
Dr Lisa Turnbull
Professor Tim Goodship
Effect of plasma exchanges (PEs) in 2 cases of dense deposit disease (DDD)2008
Dr Veronique Fremaux-Bacchi
Professor Tim Goodship
Efficacy of plasma therapy in atypical hemolytic uremic syndrome with complement factor H mutations2008
Dr Lisa Turnbull
Professor Tim Goodship
Failure of prophylactic plasma exchanges (PEs) to prevent end-stage renal failure (ESRF) in MCP mutation-related atypical hemolytic uremic syndrome (aHUS)2008
Dr Veronique Fremaux-Bacchi
Professor Tim Goodship
Membrane cofactor protein mutations in atypical hemolytic uremic syndrome (aHUS), fatal Stx-HUS, C3 glomerulonephritis, and the HELLP syndrome2008
Dr Veronique Fremaux-Bacchi
Dr Lisa Turnbull
Dr Alison Brown
Dr Nadeem Moghal
Professor Tim Goodship
et al.
Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome2008
Dr Lisa Turnbull
Professor Tim Goodship
Plasma therapy in atypical haemolytic uremic syndrome: Lessons from a family with a factor H mutation2008
Dr Lisa Turnbull
Dr Veronique Fremaux-Bacchi
Professor Tim Goodship
The complement factor H R1210C mutation is associated with atypical hemolytic uremic syndrome2008
Dr Lisa Turnbull
Professor Tim Goodship
The European MPGN registry2008
Professor David Kavanagh
Dr Matthew Edey
Dr Lisa Turnbull
Professor Judith Goodship
Dr Anne Lampe
et al.
A non-synonymous polymorphism (arg240his) in C4b-binding protein is associated with atypical haemolytic uraemic syndrome and leads to impaired alternative pathway cofactor activity2007
Professor Tim Goodship
Anguish over angiopathy: Hemolytic uremic syndrome2007
Professor Tim Goodship
Complement factor H and the hemolytic uremic syndrome2007
Dr Matthew Edey
Dr Lisa Turnbull
Professor Judith Goodship
Professor Tim Goodship
Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome2007
Dr Matthew Edey
Dr Lisa Turnbull
Professor Judith Goodship
Professor Tim Goodship
Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency and affect recognition functions2007
Professor Tim Goodship
Genetics of HUS2007
Professor David Kavanagh
Dr Veronique Fremaux-Bacchi
Professor Tim Goodship
Implications of the initial mutations in membrane cofactor protein (MCP; CD46) leading to atypical hemolytic uremic syndrome2007
Dr Veronique Fremaux-Bacchi
Professor Tim Goodship
Membrane cofactor protein mutations in atypical hemolytic uremic syndrome (aHUS), fatal Stx-HUS, C3 glomerulonephritis and the HELLP syndrome2007
Professor Tim Goodship
Microangiopathies2007
Professor Tim Goodship
Modeling how CD46 deficiency predisposes to atypical hemolytic uremic syndrome2007
Dr Veronique Fremaux-Bacchi
Professor Tim Goodship
Mutations in complement C3 predispose to development of atypical haemolytic uraemic syndrome2007
Professor Tim Goodship
Nutritional Screening in Patients on Hemodialysis: Is Subjective Global Assessment an Appropriate Tool?2007
Professor David Kavanagh
Dr Veronique Fremaux-Bacchi
Professor Tim Goodship
Screening for complement system abnormalities in patients with atypical hemolytic uremic syndrome2007
Professor David Kavanagh
Rachel Burgess
Professor Judith Goodship
Professor Tim Goodship
The decay accelerating factor mutation I197V found in hemolytic uraemic syndrome does not impair complement regulation2007
Dr Veronique Fremaux-Bacchi
Professor Tim Goodship
The factor H-aHUS mutation database and website: Update and integration of MCP and FI mutations with structural models2007
Dr Veronique Fremaux-Bacchi
Professor Tim Goodship
The interactive factor H-atypical hemolytic uremic syndrome mutation database and website: Update and integration of membrane cofactor protein and factor I mutations with structural models2007
Professor David Kavanagh
Professor Tim Goodship
Update on evaluating complement in hemolytic uremic syndrome2007
Dr Veronique Fremaux-Bacchi
Professor Tim Goodship
Where next with atypical hemolytic uremic syndrome?2007
Professor Tim Goodship
A common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of age-related macular degeneration2006
Professor Tim Goodship
An interactive web database of Factor H-associated haemolytic ureamic syndrome mutations: Insights into the structural consequences of disease-associated mutations2006
Professor Tim Goodship
An interactive web database of factor H-associated hemolytic uremic syndrome mutations: Insights into the structural consequences of disease-associated mutations2006
Professor David Kavanagh
Professor Tim Goodship
Dr Anna Richards
Atypical haemolytic uraemic syndrome2006
Dr Julian Venables
Dr Lisa Turnbull
Dr David Bourn
Dr Martha Lucia Diaz Torres
Dr Michael Jackson
et al.
Atypical haemolytic uraemic syndrome associated with a hybrid complement gene2006
Professor Tim Goodship
Atypical HUS and complement dysregulation2006
Dr Lisa Turnbull
Professor Tim Goodship
Complement factor H-associated atypical hemolytic uremic syndrome in monozygotic twins: Concordant presentation, discordant response to treatment2006
Dr Michael Jackson
Dr Lisa Turnbull
Professor Judith Goodship
Dr Liz Kemp
Professor Tim Goodship
et al.
De novo gene conversion in the RCA gene cluster (1q32) causes mutations in complement factor H associated with atypical hemolytic uremic syndrome2006
Professor David Kavanagh
Dr Anna Richards
Rachel Burgess
Professor Judith Goodship
Professor Tim Goodship
et al.
Does complement factor B have a role in the pathogenesis of atypical HUS?2006
Professor Tim Goodship
Factor H genotype-phenotype correlations: Lessons from aHUS, MPGN II, and AMD2006
Dr Lisa Turnbull
Professor Tim Goodship
Favorable long-term outcome after liver-kidney transplant for recurrent hemolytic uremic syndrome associated with a factor H mutation2006
Professor David Kavanagh
Professor Tim Goodship
Membrane cofactor protein and factor I: Mutations and transplantation2006
Professor Tim Goodship
No association betiveen 2 functional single nucleolide polymorphisms (SNPs) in complement factor H (CFR) and SLE2006
Professor Tim Goodship
Outcome of renal transplantation in patients with non-Shiga toxin-associated hemolytic uremic syndrome: Prognostic significance-of genetic background2006
Dr Mark Boxall
Professor Tim Goodship
Dr Alison Brown
Professor Thomas von Zglinicki
Telomere shortening and haemodialysis2006
Professor Judith Goodship
Dr Lisa Turnbull
Dr Julian Venables
Daniel Routledge
Professor Kevin Marchbank
et al.
The genomic organisation of the RCA cluster, including CFH, predisposes to gene conversion and nonhomologous recombination as a cause of atypical haemolytic uraemic syndrome2006
Professor David Kavanagh
Dr Liz Kemp
Professor Judith Goodship
Professor Tim Goodship
Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome2005
Professor Tim Goodship
Dr Lisa Turnbull
Posttransplantation cytomegalovirus-induced recurrence of atypical hemolytic uremic syndrome associated with a factor H mutation: Successful treatment with intensive plasma exchanges and ganciclovir2005
Dr Veronique Fremaux-Bacchi
Professor Judith Goodship
Dr Lisa Turnbull
Professor Tim Goodship
The development of atypical haemolytic-uraemic syndrome is influenced by susceptibility factors in factor H and membrane cofactor protein: Evidence from two independent cohorts2005
Dr Lisa Turnbull
Professor Judith Goodship
Professor Tim Goodship
The development of atypical hemolytic uremic syndrome is not influenced by thrombophilia susceptibility factors [15]2005
Dr Lisa Turnbull
Professor Tim Goodship
Atypical relapse of hemolytic uremic syndrome after transplantation2004
Dr Lisa Turnbull
Professor Tim Goodship
Challenges in the management if infantile factor H associated hemolytic uremic syndrome2004
Claire Lambert
Professor Tim Goodship
Familial hemolytic uremic syndrome: a privileged observation2004
Professor Tim Goodship
Inherited dysregulation of the complement system2004
Professor Judith Goodship
Professor Tim Goodship
Lack of major involvement of human uroplakin genes in vesicoureteral reflux: Implications for disease heterogeneity2004
Dr Liz Kemp
Professor Tim Goodship
Modeling how deficiency of membrane cofactor protein (MCP; CD46) predisposes to atypical hemolytic uremic syndrome2004
Professor Tim Goodship
Dr Liz Kemp
Mutations in CD46, a complement regulatory protein, predispose to atypical HUS2004
Professor John Sayer
Dr Georgina Carr
Professor Simon Pearce
Professor Tim Goodship
Professor Nicholas Simmons
et al.
Disordered calcium crystal handling in antisense CLC-5-treated collecting duct cells2003
Dr Chris Redfern
Professor Tim Goodship
Effect of insulin upon protein degradation in cultured human myocytes2003
Professor Judith Goodship
Professor Tim Goodship
Familial haemolytic uraemic syndrome and mutations in membrane cofactor protein (MCP; CD46) of the complement system2003
Professor Judith Goodship
Dr Anne Lampe
Professor Tim Goodship
Familial hemolytic uremic syndrome and mutations in membrane cofactor protein (MCP; CD46) of the complement system2003
Professor Tim Goodship
Fibrinogen in hemodialysis: The worst of both worlds?2003
Dr Anna Richards
Professor Judith Goodship
Dr Anne Lampe
Professor Tim Goodship
Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome2003
Dr Mark Boxall
Barbara Keys
Professor Thomas von Zglinicki
Professor Tim Goodship
Peripheral blood mononuclear cell telomere length is unaltered in hemodialysis despite increased oxidative stress.2003
Professor Tim Goodship
Anodipsia nervosa a variant of anorexia in patients with end-stage renal disease2002
Professor John Sayer
Dr Georgina Carr
Professor Nicholas Simmons
Professor Tim Goodship
Antisense CLC-5 disrupts acidic endosomes and endocytosis in murine collecting duct cells2002
Dr Jonathan Louden
Professor Kim Bartlett
Dr David Reaich
Professor Tim Goodship
Effects of feeding on albumin synthesis in hypoalbuminemic hemodialysis patients2002
Professor Tim Goodship
Dr Nicholas Hoenich
Timothy Hawkins
Dr Peter Fawcett
Dr John Tapson
et al.
Is decreased treatment time in hemodialysis patients harmful if solute clearance is maintained?2002
Professor Tim Goodship
Molecular modelling of the C-terminal domains of factor H of human complement: A correlation between haemolytic uraemic syndrome and a predicted heparin binding site2002
Dr Rosemary Donne
Dr Margaret Little
Professor Tim Goodship
Recurrence of hemolytic uremic syndrome after live related renal transplantation associated with subsequent de novo disease in the donor2002
Dr Chris Redfern
Professor Tim Goodship
Skeletal muscle mRNA levels for cathepsin B, but not components of the ubiquitin-proteasome pathway, are increased in patients with lung cancer referred for thoracotomy2002
Dr Chris Redfern
Professor Kim Bartlett
Professor Robert Wilkinson
Professor Tim Goodship
Sodium bicarbonate treatment and ubiquitin gene expression in acidotic human subjects with chronic renal failure2002
Professor Judith Goodship
Professor Tim Goodship
Anne Hattersley
Solitary functioning kidney and diverse genital tract malformations associated with hepatocyte nuclear factor-1 beta mutations2002
Professor Tim Goodship
Solution structures of complement components by X-ray and neutron scattering and analytical ultracentrifugation2002
Professor Judith Goodship
Professor Tim Goodship
The genetics and pathogenesis of haemolytic uraemic syndrome and thrombotic thrombocytopenic purpura2002
Dr Mark Buddles
Dr Rosemary Donne
Professor Judith Goodship
Professor Tim Goodship
Factor H mutations in hemolytic uremic syndrome cluster in exons 18-20, a domain important for host cell recognition2001
Professor Tim Goodship
Genotypic and phenotypic spectrum in tricho-rhino-phalangeal syndrome types I and III2001
Professor Tim Goodship
Emeritus Professor John Gibson
Nutritional status of patients undergoing lung cancer operations2001
Professor Tim Goodship
Emeritus Professor John Gibson
The influence of nutritional status on complications after operations for lung cancer2001
Professor John Sayer
Dr Gavin Stewart
Dr Stefan Boese
Dr Michael Gray
Professor Simon Pearce
et al.
The voltage-dependent of Cl- channel ClC-5 and plasma membrane Cl- conductances of mouse renal collecting duct cells (mIMCD-3)2001
Dr Jonathan Louden
Professor Tim Goodship
Acid-Base in Renal Failure: What have isotope studies in humans told us about the nutritional effects of acidosis in dialysis?2000
Dr Jonathan Louden
Professor Tim Goodship
An assessment of the methods available to determine nutritional equilibrium in patients with chronic renal failure2000
Dr Mark Buddles
Dr Rosemary Donne
Amy Richards
Professor Judith Goodship
Professor Tim Goodship
et al.
Complement factor H gene mutation associated with autosomal recessive atypical hemolytic uremic syndrome2000
Professor Tim Goodship
Janet Stoddart
Dr Alison Brown
Dr Michael Ward
Dr John Owen
et al.
Long-term follow-up of patients presenting to adult nephrologists with chronic pyelonephritis and 'normal' renal function2000
Professor Tim Goodship
Professor Judith Goodship
Primary, nonsyndromic vesicoureteric reflux and its nephropathy is genetically heterogeneous, with a locus on chromosome 12000
Professor Tim Goodship
Professor Judith Goodship
A major locus for vesicoureteric reflux and its nephropathy1999
Dr Jonathan Louden
Professor Tim Goodship
Acidosis and nutrition1999
Professor Tim Goodship
Dr Peter Fawcett
Dr John Tapson
Adequacy of haemodialysis - the long and the short of it1999
Professor Tim Goodship
Angiotensin converting enzyme inhibitors (ACE-I) and bilateral nephrectomy in the treatment of hypertension in non-diarrhoeal haemolytic uraemic syndrome (d-HUS) - a retrospective study.1999
Professor Tim Goodship
Dr Michael Ward
Audit of hospital haemodialysis delivery1999
Professor Tim Goodship
Dr John Owen
Jan Stoddart
Dr Michael Ward
Professor Robert Wilkinson
et al.
Chronic pyelonephritis. A re-evaluation of prognostic factors for the development of renal impairment1999
Professor Tim Goodship
Professor Kim Bartlett
Does clenbuterol affect whole body protein turnover in adults with end-stage renal failure managed by CAPD?1999
Dr Rosemary Donne
Professor Judith Goodship
Professor Tim Goodship
Familial relapsing haemolytic uraemic syndrome and complement factor H deficiency1999
Professor Judith Goodship
Professor Tim Goodship
von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome1999
Dr Nicholas Hoenich
Dr Chris Redfern
Professor Tim Goodship
Production of interleukin 1 receptor antagonist and interleukin 1 during haemodialysis with cellulose membranes1994
Professor Stephen Proctor
Professor Tim Goodship
Immune complex glomerulonephritis, myasthenia gravis and
compensated hypothyroidism in a patient following allogeneic bone marrow transplantation
1993