Publications by Professor Majlinda Lako - ePrints

Browsing publications by Professor Majlinda Lako.

Newcastle Authors	Title	Year
Dr Maria Georgiou Alex Chaudhary Dr Joseph Collin Dr Rachel Queen Dr Birthe Hilgen et al.	Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: A Comprehensive Validation Using Drugs and Compounds Affecting the Retina	2022
Dr Laura Wadkin Professor Majlinda Lako Dr Nick Parker Professor Anvar Shukurov	A mathematical modelling framework for the regulation of intra-cellular OCT4 in human pluripotent stem cells	2021
Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Professor Francisco Figueiredo Professor Lyle Armstrong et al.	A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells	2021
Professor Francisco Figueiredo Dr Jeffry Hogg Arthur Okonkwo Dr Gustavo Figueiredo Professor Majlinda Lako et al.	A systematic review of cellular therapies for the treatment of limbal stem cell deficiency affecting one or both eyes	2021
Dr Marzena Kurzawa-Akanbi Professor David Steel Professor Majlinda Lako	Age-related macular degeneration - Biomarkers and therapies	2021
Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Professor David Steel Professor Majlinda Lako et al.	Dissecting the transcriptional and chromatin accessibility heterogeneity of proliferating cone precursors in human retinoblastoma tumours by single cell sequencing- opening pathways to new therapeutic strategies?	2021
Dr Darin Zerti Marina MoyaMolina Dr Birthe Hilgen Dr Roman Bauer Professor Majlinda Lako et al.	IGFBPs mediate IGF-1’s functions in retinal lamination and photoreceptor development during pluripotent stem cell differentiation to retinal organoids	2021
Professor Lyle Armstrong Dr Joseph Collin Dr Islam Mostafa Dr Rachel Queen Professor Francisco Figueiredo et al.	In the eye of the storm: SARS-CoV-2 infection and replication at the ocular surface?	2021
Dr Laura Wadkin Dr Sirio Orozco Fuentes Dr Irina Neganova Professor Majlinda Lako Dr Andrew Baggaley et al.	OCT4 expression in human embryonic stem cells: spatio-temporal dynamics and fate transitions	2021
Professor Francisco Figueiredo Professor Majlinda Lako	Pathophysiology of aniridia-associated keratopathy: Developmental aspects and unanswered questions	2021
Dr Chunbo Yang Dr Maria Georgiou Rob Atkinson Dr Joseph Collin Professor Lyle Armstrong et al.	Pre-mRNA Processing Factors and Retinitis Pigmentosa: RNA Splicing and Beyond	2021
Professor Majlinda Lako Professor Francisco Figueiredo	Referral Patterns of Patients with Limbal Stem Cell Deficiency to a Specialized Tertiary Center in the United Kingdom	2021
Nik Tzoumas Dr Dean Hallam Professor Claire Harris Professor Majlinda Lako Professor David Kavanagh et al.	Revisiting the role of factor H in age-related macular degeneration: Insights from complement-mediated renal disease and rare genetic variants.	2021
Ivo Djidrovski Dr Maria Georgiou Marina MoyaMolina Dr Git Chung Professor Majlinda Lako et al.	SARS-CoV-2 infects an upper airway model derived from induced pluripotent stem cells	2021
Dr Rachel Queen Professor Majlinda Lako Zerti Zerti	Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics	2021
Dr Sirio Orozco Fuentes Dr Laura Wadkin Dr Irina Neganova Professor Majlinda Lako Dr Andrew Baggaley et al.	Spatio-temporal analyses of transcription factor expression and fate transitions in a hESC colony	2021
Professor Majlinda Lako Professor Miodrag Stojkovic	Stem cells and hearing loss	2021
Dr Darin Zerti Dr Birthe Hilgen Dr Joseph Collin Professor Lyle Armstrong Professor Evelyne Sernagor et al.	Transplanted pluripotent stem cell‐derived photoreceptor precursors elicit conventional and unusual light responses in mice with advanced retinal degeneration	2021
Dr Ali Ghareeb Professor Majlinda Lako Professor David Steel	Coculture techniques for modeling retinal development and disease, and enabling regenerative medicine	2020
Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Dr Birthe Hilgen Maria Georgiou et al.	Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface	2020
Edvinas Cerniauskas Dr Marzena Kurzawa-Akanbi Dr Long Xie Dr Dean Hallam Marina Moya Molina et al.	Complement modulation reverses pathology in Y402H-retinal pigment epithelium cell model of AMD by restoring lysosomal function	2020
Dr Darin Zerti Dr Birthe Hilgen Majed Felemban Dr Ali Ghareeb Dr Min Yu et al.	Developing a simple method to enhance the generation of cone and rod photoreceptors in pluripotent stem cell‐derived retinal organoids	2020
Dr Jarmila Spegarova Dr Karin Engelhardt Dr Helen Griffin Dr Aneta Mikulasova Dr Meghan Acres et al.	Germline TET2 loss-of-function causes childhood immunodeficiency and lymphoma	2020
Dr Valeria Chichagova Dr Gerrit Hilgen Dr Ali Ghareeb Madeleine Carter Professor Evelyne Sernagor et al.	Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line‐ and method‐dependent	2020
Dr Sanja Bojic Professor Lyle Armstrong Professor Majlinda Lako Dr Roman Bauer Professor Miodrag Stojkovic et al.	Platform to study intracellular polystyrene nanoplastic pollution and clinical outcomes	2020
Dr Ali Ghareeb Professor Majlinda Lako Professor Francisco Figueiredo	Recent Advances in Stem Cell Therapy for Limbal Stem Cell Deficiency: A Narrative Review	2020
Dr Maria Georgiou Dr Valeria Chichagova Dr Birthe Hilgen Professor Evelyne Sernagor Professor Lyle Armstrong et al.	Room temperature shipment does not affect the biological activity of pluripotent stem cell-derived retinal organoids	2020
Dr Rachel Queen Professor Majlinda Lako	SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes	2020
Dr Laura Wadkin Dr Sirio Orozco Fuentes Dr Irina Neganova Professor Majlinda Lako Professor Anvar Shukurov et al.	The recent advances in the mathematical modelling of human pluripotent stem cells	2020
Dr Rachel Queen Dr Simon Cockell Professor Majlinda Lako	Understanding the complexity of retinal and pluripotent stem cell derived retinal organoids with single cell RNA sequencing: current progress, remaining challenges and future prospectives	2020
Dr Adriana Buskin Professor Majlinda Lako	AAV-Mediated Gene Augmentation Therapy Restores Critical Functions in Mutant PRPF31+/− iPSC-Derived RPE Cells	2019
Dr Carla Jackson Dr Roman Bauer Dr Joseph Collin Dr Birthe Hilgen Dr Darin Zerti et al.	An integrated transcriptional analysis of the developing human retina	2019
Dr Joseph Collin Dr Darin Zerti Dr Rachel Queen Dr Roman Bauer Dr Jonathan Coxhead et al.	CRX Expression in Pluripotent Stem Cell‐Derived Photoreceptors Marks a Transplantable Subpopulation of Early Cones	2019
Majed Felemban Dr Birthe Hilgen Dr Darin Zerti Dr Nicola Hunt Dr Dean Hallam et al.	Decellularised extracellular matrix-derived peptides from neural retina and retinal pigment epithelium enhance the expression of synaptic markers and light responsiveness of human pluripotent stem cell derived retinal organoids	2019
Dr Joseph Collin Dr Rachel Queen Dr Darin Zerti Dr Birthe Hilgen Raf Hussain et al.	Deconstructing Retinal Organoids: Single cell RNA-Seq reveals the cellular components of human pluripotent stem cell-derived retina	2019
Dr Valeria Chichagova Dr Birthe Hilgen Majed Felemban Dr Maria Georgiou Professor Lyle Armstrong et al.	Differentiation of Retinal Organoids from Human Pluripotent Stem Cells	2019
Dr Laura Wadkin Dr Sirio Orozco Fuentes Dr Irina Neganova Dr Sanja Bojic Dr Alex Laude et al.	Seeding hESCs to achieve optimal colony clonality	2019
Dr Carla Jackson Dr Joseph Collin Dr Rachel Queen Dr Birthe Hilgen Dr Darin Zerti et al.	Systematic Comparison of Retinal Organoid Differentiation from Human Pluripotent Stem Cells Reveals Stage Specific, Cell Line, and Methodological Differences	2019
Dr Sai Kolli Dr Sanja Bojic Dr Ali Ghareeb Dr Marzena Kurzawa-Akanbi Professor Francisco Figueiredo et al.	The Role of Nerve Growth Factor in Maintaining Proliferative Capacity, Colony‐Forming Efficiency, and the Limbal Stem Cell Phenotype	2019
Dr Osagie Izuogu Dr Carla Mellough Dr Joseph Collin Dr Richard Gallon Francesco Kumara Mastrorosa et al.	Analysis of human ES cell differentiation establishes that the dominant isoforms of the lncRNAs RMST and FIRRE are circular	2018
Dr Sanja Bojic Dr Dean Hallam Nuno Alcada Dr Ali Ghareeb Dr Rachel Queen et al.	CD200 expression marks a population of quiescent limbal epithelial stem cells with holoclone forming ability	2018
Dr Valeria Chichagova Dr Dean Hallam Dr Joseph Collin Dr Darin Zerti Dr Birthe Hilgen et al.	Cellular regeneration strategies for macular degeneration: past, present and future	2018
Dr Laura Wadkin Dr Sirio Orozco Fuentes Dr Irina Neganova Dr Alex Laude Professor Majlinda Lako et al.	Correlated random walks of human embryonic stem cells in vitro	2018
Dr Charlie Osei-Bempong Dr Ali Ghareeb Professor Majlinda Lako Professor Francisco Figueiredo	Defining the optimal cryoprotectant and concentration for cryopreservation of limbal stem cells	2018
Dr Sanja Bojic Dr Joseph Collin Dr Min Yu Professor Lyle Armstrong Professor Francisco Figueiredo et al.	Differences in the activity of endogenous BMP signalling impact on the ability of induced pluripotent stem cells to differentiate to corneal epithelial like cells	2018
Dr Jane Carr-Wilkinson Dr Nilendran Prathalingam Dr Deepali Pal Dr Mohammad Moad Dr Peter James et al.	Differentiation of human embryonic stem cells to sympathetic neurons: A model for understanding neuroblastoma pathogenesis.	2018
Dr Adriana Buskin Dr Lili Zhu Dr Valeria Chichagova Dr David Dolan Dr Joseph Collin et al.	Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa	2018
Dr iRINA Neganova Lewis Cotts Dr Andrew Banks Katja Gassner Professor Lyle Armstrong et al.	EDG5 plays an important role in induction and maintenance of pluripotency	2018
Professor Lyle Armstrong Professor Majlinda Lako Professor Miodrag Stojkovic	Ethical and safety issues of stem cell-based therapy	2018
Majed Felemban Dr Birthe Hilgen Dr Nicola Hunt Dr Dean Hallam Dr Darin Zerti et al.	Extracellular matrix components expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix	2018
Minjin Jeong Professor Majlinda Lako Professor Lyle Armstrong	Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells	2018
Heather Crawford Professor Majlinda Lako Dr Nicholas Hole Professor Colin Jahoda	Hair Follicle Dermal Cells Support Expansion of Murine and Human Embryonic and Induced Pluripotent Stem Cells and Promote Haematopoiesis in Mouse Cultures	2018
Dr Dean Hallam Dr Birthe Hilgen Dr Lili Zhu Dr Min Yu Dr Sanja Bojic et al.	Human induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient dependent efficiency	2018
Dr Dean Hallam David Rawlings David Steel Professor Lyle Armstrong Professor Majlinda Lako et al.	In Reply to the Letter to the Editor from Hallam et al.: An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age-Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure	2018
Dario Melguizo Sanchis Dr Yaobo Xu Dheraj Taheem Dr Min Yu Dr Katarzyna Tilgner et al.	iPSC modelling of severe aplastic anemia reveals impaired differentiation and telomere shortening in blood progenitors	2018
Dr Birthe Hilgen Majed Felemban Alex Sharpe Dr Roman Bauer Dr Dean Hallam et al.	Laminin γ3 plays an important role in retinal lamination, photoreceptor organisation and ganglion cell differentiation	2018
Dr Gustavo Figueiredo Dr Oliver Baylis Professor Majlinda Lako Professor Francisco Figueiredo	Outcomes of penetrating keratoplasty following autologous cultivated limbal epithelial stem cell transplantation	2018
Dr Oliver Russell Pavandeep Rai Dr Amy Reeve Dr Karolina Rygiel Professor Majlinda Lako et al.	Preferential amplification of a human mitochondrial DNA deletion in vitro and in vivo	2018
Dr Tomas Barta Professor Majlinda Lako Professor Lyle Armstrong	Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study	2018
Professor Majlinda Lako	Special Series: Transplantation of Stem Cells into the Eye	2018
Dr Dean Hallam Dr Valeria Chichagova Professor David Steel Professor Majlinda Lako	The application of biomaterials to tissue engineering neural retina and retinal pigment epithelium	2018
Dr Nicola Hunt Dr Dean Hallam Dr Carla Jackson Dr Jinju Chen Professor Majlinda Lako et al.	3D culture of human pluripotent stem cells in RGD-alginate hydrogel improves retinal tissue development	2017
Dr Irina Neganova Dr Valeria Chichagova Professor Lyle Armstrong Professor Majlinda Lako	A critical role for p38MAPK signalling pathway during reprogramming of human fibroblasts to iPSCs	2017
Dr Dean Hallam Dr Joseph Collin Dr Sanja Bojic Dr Valeria Chichagova Dr Adriana Buskin et al.	An iPSC patient specific model of CFH (Y402H) polymorphism displays characteristic features of AMD and indicates a beneficial role for UV light exposure	2017
Ellie Meader Dr Tomas Barta Dario Melguizo Sanchis Dr Katarzyna Tilgner Professor Lyle Armstrong et al.	Brief Report: Pluripotent Stem Cell-Derived Hematopoietic Progenitors Are Unable to Downregulate Key Epithelial-Mesenchymal Transition-Associated miRNAs	2017
Dr Gustavo Figueiredo Dr Julian De Havilland Professor Majlinda Lako Professor Francisco Figueiredo	Cell Therapy in Practice	2017
Dario Melguizo Sanchis Dr Sujith Samarasinghe Professor Lyle Armstrong Professor Majlinda Lako	Concise review: Getting to the core of inherited bone marrow failures	2017
Dr Laura Wadkin Dr Irina Neganova Dr Nick Parker Dr Valeria Chichagova Georgina Kay-Black et al.	Dynamics of single human embryonic stem cells and their pairs: a quantitative analysis	2017
Dr Gustavo Figueiredo Dr Sanja Bojic Professor Che Connon Dr Ricardo Martins Gouveia Professor Francisco Figueiredo et al.	Gamma-irradiated human amniotic membrane decellularised with sodium dodecylsulfate is a more efficient substrate for the ex vivo expansion of limbal stem cells	2017
Dr Roly Megaw Dr Carla Mellough Professor Majlinda Lako	Gelsolin dysregulation causes photoreceptor loss in induced pluripotent stem cell and animal models of retinitis pigmentosa	2017
Professor Majlinda Lako	Hepatic differentiation of human iPSCs in different 3D models: A comparative study	2017
Dr Laura Wadkin Dr Sirio Orozco Fuentes Dr Nick Parker Professor Anvar Shukurov Dr Irina Neganova et al.	Human embryonic stem cell colony formation: statistical analysis and agent-based modelling	2017
Dr Valeria Chichagova Dr Dean Hallam Dr Joseph Collin Dr Adriana Buskin Dr Gabriele Saretzki et al.	Human iPSC disease modelling reveals functional and structural defects in retinal pigment epithelial cells harbouring the m.3243A>G mitochondrial DNA mutation	2017
Dr Chunbo Yang Dr Yaobo Xu Dr Min Yu Dr David Lee Dr John O'Sullivan et al.	Induced pluripotent stem cell modelling of HLHS underlines the contribution of dysfunctional NOTCH signalling to impaired cardiogenesis	2017
Professor Majlinda Lako Professor Lyle Armstrong	Multiplex High-Throughput Targeted Proteomic Assay to Identify Induced Pluripotent Stem Cells	2017
Professor Majlinda Lako Professor Lyle Armstrong	Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience	2017
Professor Majlinda Lako Professor Miodrag Stojkovic	Stem Cell-Based Therapy in Transplantation and Immune-Mediated Diseases	2017
Professor Lyle Armstrong Professor Majlinda Lako	Towards optimisation of induced pluripotent cell culture: Extracellular acidification results in growth arrest of iPSC prior to nutrient exhaustion	2017
Dr Joseph Collin Dr Lili Zhu Professor Lyle Armstrong Dr Irina Neganova Professor Majlinda Lako et al.	A Novel role for miR-1305 in Regulation of Pluripotency-Differentiation Balance, Cell Cycle and Apoptosis in Human Pluripotent Stem Cells	2016
Professor Majlinda Lako Professor Lyle Armstrong Professor Miodrag Stojkovic	Aging of Stem and Progenitor Cells: Mechanisms, Impact on Therapeutic Potential, and Rejuvenation	2016
Dr Min Yu Dr Sanja Bojic Dr Gustavo Figueiredo Dr Julian De Havilland Professor Anne Dickinson et al.	An important role for adenine, cholera toxin, hydrocortisone and triiodothyronine inthe proliferation, self-renewal and differentiation of limbal stem cells in vitro	2016
Professor Majlinda Lako	Development Refractoriness of MLL-Rearranged Human B Cell Acute Leukemias to Reprogramming into Pluripotency	2016
Dr Carla Jackson Professor Majlinda Lako	How to build a human	2016
Dr Tomas Barta Dr Joseph Collin Dr Irina Neganova Professor Lyle Armstrong Professor Majlinda Lako et al.	Inhibition of miR-145 Enhances Reprogramming of Human Dermal Fibroblasts to Induced Pluripotent Stem Cells	2016
Professor Majlinda Lako	Insights into islet development and biology through characterization of a human iPSC-derived endocrine pancreas model	2016
Dr Irina Neganova Dr Evgeniya Shmeleva Dr Jennifer Munkley Dr Valeria Chichagova Dr George Anyfantis et al.	JNK/SAPK signalling is essential for efficient reprogramming of human fibroblasts to induced pluripotent stem cells	2016
Professor Lyle Armstrong Professor Majlinda Lako Professor Miodrag Stojkovic	Primordial Germ Cells: Current Knowledge and Perspectives	2016
Professor Majlinda Lako Professor Miodrag Stojkovic	Stem Cells, Inflammation, and Fibrosis	2016
Dr Lili Zhu Dr Aurora Gomez Duran Dr Gabriele Saretzki Dr Katarzyna Tilgner Dario Melguizo Sanchis et al.	The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages	2016
Dr Nicola Hunt Professor Majlinda Lako	Tissue engineering using pluripotent stem cells: multidisciplinary approaches to accelerate bench-to-bedside transition	2016
Dr Gustavo Figueiredo Dr Jeffry Hogg Arthur Okonkwo Dr Deborah Stocken Professor Simi Ali et al.	Understanding ocular surface inflammation in tears before and after ex vivo expanded autologous limbal stem cell transplantation	2016
Dr Joseph Collin Dr Carla Jackson Dr Birthe Hilgen Professor Majlinda Lako	Using Zinc Finger Nuclease Technology to Generate CRX-Reporter Human Embryonic Stem Cells as a Tool to Identify and Study the Emergence of Photoreceptors Precursors During Pluripotent Stem Cell Differentiation	2016
Dr Chunbo Yang Professor Majlinda Lako Professor Lyle Armstrong	Concise Review: Cardiac Disease Modeling Using Induced Pluripotent Stem Cells	2015
Dr Valeria Chichagova Dr Irene Sanchez-Vera Professor Lyle Armstrong Professor David Steel Professor Majlinda Lako et al.	Generation of Human Induced Pluripotent Stem Cells Using RNA-Based Sendai Virus System and Pluripotency Validation of the Resulting Cell Population	2015
Dr Carla Jackson Joseph Collin Mahmoud Khazim Dr Kathryn White Professor Evelyne Sernagor et al.	IGF-1 Signaling Plays an Important Role in the Formation of Three-Dimensional Laminated Neural Retina and Other Ocular Structures From Human Embryonic Stem Cells	2015
Majed Felemban Dr Nicola Hunt Dr Birthe Hilgen Dr Carla Mellough Professor Majlinda Lako et al.	Investigation of extracellular matrix (ECM) component expression in developing retina	2015
Professor Francisco Figueiredo Professor Majlinda Lako Dr Oliver Baylis Dr Gustavo Figueiredo	Patient reported outcomes before and following ex vivo cultured autologous limbal stem cell transplantation for total unilateral limbal stem cell deficiency	2015
Dr Roly Megaw Dr Carla Mellough Professor Majlinda Lako	Use of induced pluripotent stem-cell technology to understand photoreceptor cytoskeletal dynamics in retinitis pigmentosa	2015
Professor Majlinda Lako Dr Joseph Collin Dr Carla Jackson Dr Birthe Hilgen	Using zinc finger nuclease technology to generate reporter-labelled human pluripotent stem cells as a tool to optimize photoreceptor transplantation	2015
Dr Saba Habibollah Dr Katarzyna Tilgner Dr Joseph Collin Dr Tomas Barta Raf Hussain et al.	An Induced Pluripotent Stem Cell Model of Hypoplastic Left Heart Syndrome (HLHS) Reveals Multiple Expression and Functional Differences in HLHS-Derived Cardiac Myocytes	2014
Dr Irina Neganova Dr Katarzyna Tilgner Dr Adriana Buskin Iliana Paraskevopoulou Dr Stuart Atkinson et al.	CDK1 plays an important role in the maintenance of pluripotency and genomic stability in human pluripotent stem cells	2014
Professor Lyle Armstrong Professor Miodrag Stojkovic Professor Majlinda Lako	Concise Review: The Epigenetic Contribution to Stem Cell Ageing: Can We Rejuvenate Our Older Cells?	2014
Professor Majlinda Lako Professor Lyle Armstrong	Engraftment's Holy Grail: is one signal enough?	2014
Dr Carla Jackson Dr Joseph Collin Professor Evelyne Sernagor Nicholas Wride Professor David Steel et al.	Lab generated retina: Realizing the dream	2014
Professor Majlinda Lako Professor Miodrag Stojkovic	Stem Cells as New Agents for the Treatment of Infertility: Current and Future Perspectives and Challenges	2014
Sai Kolli Dr Sajjad Ahmad Professor Majlinda Lako Professor Francisco Figueiredo	Successful Application of Ex Vivo Expanded Human Autologous Oral Mucosal Epithelium for the Treatment of Total Bilateral Limbal Stem Cell Deficiency	2014
Dr Katarzyna Tilgner Dr Irina Neganova Sun Yung Chatcha Singhapol Dr Gabriele Saretzki et al.	A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors	2013
Dr Mohammad Moad Dr Deepali Pal Dr Anastasia Hepburn Dr Stuart Williamson Laura Wilson et al.	A novel model of urinary tract differentiation, tissue regeneration, and disease: Reprogramming human prostate and bladder cells into induced pluripotent stem cells	2013
Dr Oliver Baylis Professor Francisco Figueiredo Professor Majlinda Lako Dr Sajjad Ahmad	An investigation of donor and culture parameters which influence epithelial outgrowths from cultured human cadaveric limbal explants	2013
Dr Katarzyna Tilgner Dr Irina Neganova Chatcha Singhapol Dr Gabriele Saretzki Jerome Evans et al.	Brief Report: A Human Induced Pluripotent Stem Cell Model of Cernunnos Deficiency Reveals an Important Role for XLF in the Survival of the Primitive Hematopoietic Progenitors	2013
Sun Yung Dr Katarzyna Tilgner Dr Maria Ledran Dr Saba Habibollah Dr Irina Neganova et al.	Brief Report: Human Pluripotent Stem Cell Models of Fanconi Anemia Deficiency Reveal an Important Role for Fanconi Anemia Proteins in Cellular Reprogramming and Survival of Hematopoietic Progenitors	2013
Dr Mohammad Moad Dr Anastasia Hepburn Professor Majlinda Lako Dr Deepali Pal Professor Rakesh Heer et al.	Generation of induced pluripotent stem cells from human urinary tract cells	2013
Dr Aaron Ions Gardner Dr Andrew Owens Professor Majlinda Lako	Human hair follicle dermal cells provide enhanced support for both epithelial and embryonic stem cell culture proliferation and maintenance	2013
Professor Majlinda Lako Professor Miodrag Stojkovic	Mesenchymal Stem Cells for Diabetes and Related Complications	2013
Dr Alison Dickinson Professor Majlinda Lako Sai Kolli Professor Francisco Figueiredo	Outcomes of ex vivo expanded limbal stem cell transplantation in humans	2013
Dr Stuart Atkinson Professor Majlinda Lako Professor Lyle Armstrong	Potential for Pharmacological Manipulation of Human Embryonic Stem Cells	2013
Dr Charlie Osei-Bempong Professor Francisco Figueiredo Professor Majlinda Lako	The limbal epithelium of the eye A review of limbal stem cell biology, disease and treatment	2013
Stuart Atkinson Dr Joseph Collin Dr George Anyfantis Professor Majlinda Lako Professor Lyle Armstrong et al.	A Putative Role for the Immunoproteasome in the Maintenance of Pluripotency in Human Embryonic Stem Cells	2012
Dr Yan Jiang Dr Katarzyna Tilgner Dr Gabriele Saretzki Professor Majlinda Lako Professor Lyle Armstrong et al.	Derivation and functional analysis of patient specific induced pluripotent stem cells (IPSCS) as an in vitro model of chronic granulomatous disease	2012
Dr Yan Jiang Dr Katarzyna Tilgner Dr Gabriele Saretzki Professor Majlinda Lako Professor Lyle Armstrong et al.	Derivation and Functional Analysis of Patient Specific Induced Pluripotent Stem Cells as an In Vitro Model of Chronic Granulomatous Disease	2012
Dr Yan Jiang Dr Katarzyna Tilgner Dr Gabriele Saretzki Professor Majlinda Lako Professor Lyle Armstrong et al.	Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease	2012
Dr Carla Jackson Professor Evelyne Sernagor Professor David Steel Professor Majlinda Lako	Efficient Stage-Specific Differentiation of Human Pluripotent Stem Cells Toward Retinal Photoreceptor Cells	2012
Dr John Blackwood Dr Laura Greaves Laura Wilson Rob Pickard Professor Majlinda Lako et al.	Lineage tracking in situ: Where are the prostate stem cells? What are they doing?	2012
Professor Lyle Armstrong Professor Majlinda Lako Professor Miodrag Stojkovic	Our Top 10 Developments in Stem Cell Biology over the Last 30 Years	2012
Professor Majlinda Lako	SCL/TAL1 Regulates Hematopoietic Specification From Human Embryonic Stem Cells	2012
Professor Majlinda Lako	Using human pluripotent stem cells to understand our beginnings and treat disease	2012
Dr Oliver Baylis Professor Francisco Figueiredo Dr Christin Henein Professor Majlinda Lako Dr Sajjad Ahmad et al.	13 Years of Cultured Limbal Epithelial Cell Therapy: A Review of the Outcomes	2011
Dr Irina Neganova Dr Stuart Atkinson Dr Joao Passos Professor Thomas von Zglinicki Professor Lyle Armstrong et al.	An Important Role for CDK2 in G1 to S Checkpoint Activation and DNA Damage Response in Human Embryonic Stem Cells	2011
Dr Joseph Collin Professor Majlinda Lako	Concise Review: Putting a Finger on Stem Cell Biology: Zinc Finger Nuclease-Driven Targeted Genetic Editing in Human Pluripotent Stem Cells	2011
Sun Yung Dr Maria Ledran Ian Dimmick Dr Nicholas Slater Iliana Paraskevopoulou et al.	Large-scale transcriptional profiling and functional assays reveal important roles for Rho-GTPase signalling and SCL during haematopoietic differentiation of human embryonic stem cells	2011
Professor Majlinda Lako	Law, Ethics, Religion, and Clinical Translation in the 21st Century - A Conversation with Anthony D. Ho	2011
Professor Majlinda Lako	Law, Ethics, Religion, and Clinical Translation in the 21st Century-A Conversation with Cinzia Rota	2011
Professor Miodrag Stojkovic Professor Majlinda Lako	Neural Stem Cells, a Step Closer to Clinic?	2011
Dr George Anyfantis Professor Lyle Armstrong Professor Majlinda Lako	Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage	2011
Dr Katarzyna Tilgner Dr Stuart Atkinson Sun Yung Anna Golebiewska Professor Miodrag Stojkovic et al.	Expression of GFP Under the Control of the RNA Helicase VASA Permits Fluorescence-Activated Cell Sorting Isolation of Human Primordial Germ Cells	2010
Dr Maria Ledran Professor Majlinda Lako	Hematopoietic differentiation from human ESCs as a model for developmental studies and future clinical translations. Invited review following the FEBS Anniversary Prize received on 5 July 2009 at the 34th FEBS Congress in Prague	2010
Professor Lyle Armstrong Dr Katarzyna Tilgner Dr Gabriele Saretzki Dr Stuart Atkinson Professor Miodrag Stojkovic et al.	Human Induced Pluripotent Stem Cell Lines Show Stress Defense Mechanisms and Mitochondrial Regulation Similar to Those of Human Embryonic Stem Cells	2010
Dr Katarzyna Tilgner Dr Chunbo Yang Dr Irina Neganova Professor Lyle Armstrong Professor Majlinda Lako et al.	Human-Induced Pluripotent Stem Cell-Derived Models for the Study of Spinal Muscular Atrophy	2010
Professor Majlinda Lako Professor Lyle Armstrong Professor Miodrag Stojkovic	Induced Pluripotent Stem Cells : It Looks Simple but Can Looks Deceive?	2010
Professor Majlinda Lako	Law, Ethics, Religion, and Clinical Translation in the 21(st) Century - A Discussion with Pete Coffey	2010
Professor Majlinda Lako	Law, Ethics, Religion, and Clinical Translation in the 21st Century - A Discussion with Stephen Bellamy	2010
Professor Majlinda Lako	Law, Ethics, Religion, and Clinical Translation in the 21st Century-A Conversation with Il-Hoan Oh	2010
Professor Majlinda Lako	Law, Ethics, Religion, and Clinical Translation in the 21st Century-A Discussion with Andrew Webster	2010
Professor Majlinda Lako	Law, Ethics, Religion, and Clinical Translation in the 21st Century-A Discussion with Derek Hei	2010
Professor Majlinda Lako	Law, Ethics, Religion, and Clinical Translation in the 21st Century-A Discussion with John Sinden	2010
Dr Stuart Atkinson Professor Lyle Armstrong Professor Derek Mann Professor Majlinda Lako	Opposing Putative Roles for Canonical and Noncanonical NF kappa B Signaling on the Survival, Proliferation, and Differentiation Potential of Human Embryonic Stem Cells	2010
Dr Katarzyna Tilgner Professor Lyle Armstrong Professor Majlinda Lako	Positive effect of human ESC conditioned medium on somatic cell reprogramming	2010
Professor Todd Marder Professor Majlinda Lako	Retinoid supplementation of differentiating human neural progenitors and embryonic stem cells leads to enhanced neurogenesis in vitro	2010
Sai Kolli Dr Sajjad Ahmad Professor Majlinda Lako Professor Francisco Figueiredo	Successful Clinical Implementation of Corneal Epithelial Stem Cell Therapy for Treatment of Unilateral Limbal Stem Cell Deficiency	2010
Dr Aiqing Chen Bernard Siow Professor Andrew Blamire Professor Majlinda Lako Dr Gavin Clowry et al.	Transplantation of magnetically labeled mesenchymal stem cells in a model of perinatal brain injury	2010
Dr Meenakshi Choudhary Professor Majlinda Lako Professor Miodrag Stojkovic Professor Alison Murdoch	"Beauty and Beast'' molecule; HA in early human development	2009
Dr Meenakshi Choudhary Professor Majlinda Lako Professor Miodrag Stojkovic Professor Alison Murdoch	"Beauty and Beast" molecule: HA in early human development	2009
Dr Irina Neganova Dr Stuart Atkinson Dr George Anyfantis Dr Owen Hughes Professor Tom Strachan et al.	A role for NANOG in G1 to S transition in human embryonic stem cells through direct binding of CDK6 and CDC25A	2009
Professor Majlinda Lako	Balancing Work and Life: A Conversation with Barbara Knowles	2009
Professor Majlinda Lako	Balancing Work and Life: A Conversation with Fiona Watt	2009
Professor Majlinda Lako	Balancing Work and Life: A Conversation with George Daley	2009
Professor Majlinda Lako	Balancing Work and Life: A Conversation with Konrad Hochedlinger	2009
Professor Majlinda Lako	Balancing Work and Life: A Conversation with Lesley Forrester	2009
Professor Majlinda Lako	Balancing Work and Life: A Conversation with Marella de Bruijn	2009
Professor Majlinda Lako	Balancing Work and Life: A Conversation with Margaret "Peggy" Goodell	2009
Professor Majlinda Lako	Balancing Work and Life: A Conversation with Mina Bissell	2009
Professor Majlinda Lako	Balancing Work and Life: A Conversation with Sean Morrison	2009
Professor Majlinda Lako	Balancing Work and Life: An Interview with Connie Eaves	2009
Professor Majlinda Lako	Balancing Work and Life: An Interview with Kathleen Sakamoto	2009
Professor Majlinda Lako	Balancing Work and Life: Finding Our Inspirations	2009
Professor Majlinda Lako	Consensus Guidance for Banking and Supply of Human Embryonic Stem Cell Lines for Research Purposes	2009
Anna Golebiewska Stuart Atkinson Professor Majlinda Lako Professor Lyle Armstrong	Epigenetic Landscaping During hESC Differentiation to Neural Cells	2009
Dr Irina Neganova Stuart Atkinson Professor Majlinda Lako	Expression and functional analysis of G1 to S regulatory components reveals an important role for CDK2 in cell cycle regulation in human embryonic stem cells	2009
Professor Majlinda Lako Dr Irina Neganova Professor Lyle Armstrong	G(1) to S transition and pluripotency Two sides of the same coin?	2009
Dr Carla Jackson Professor David Steel Professor Majlinda Lako	Genetic basis of inherited macular dystrophies and implications for stem cell therapy	2009
Dr Chunbo Yang Dr Rebecca Stewart Dr George Anyfantis Stuart Atkinson Dr Gabriele Saretzki et al.	A key role for telomerase reverse transcriptase unit in modulating human embryonic stem cell proliferation, cell cycle dynamics, and in vitro differentiation	2008
Dr Sajjad Ahmad Sai Kolli Ian Dimmick Professor Lyle Armstrong Professor Francisco Figueiredo et al.	A putative role for RHAMM/HMMR as a negative marker of stem cell-containing population of human limbal epithelial cells	2008
Professor Toivo Maimets Dr Irina Neganova Professor Lyle Armstrong Professor Majlinda Lako	Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells	2008
Dr Gabriele Saretzki Theresia Walter Dr Joao Passos Dr Rebecca Stewart Dr Simon Hoare et al.	Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells	2008
Dr Maria Ledran Professor Lyle Armstrong Ian Dimmick Dr Rebecca Lang Sun Yung et al.	Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches	2008
Stuart Atkinson Dr Rebecca Stewart Professor Majlinda Lako Professor Lyle Armstrong	Epigenetic marking prepares the human HOXA cluster for activation during differentiation of pluripotent cells	2008
Dr Irina Neganova Professor Majlinda Lako	G1 to S phase cell cycle transition in somatic and embryonic stem cells	2008
Dr Katarzyna Tilgner Stuart Atkinson Anna Golebiewska Professor Miodrag Stojkovic Professor Majlinda Lako et al.	Isolation of Primordial Germ Cells from Differentiating Human Embryonic Stem Cells	2008
Sai Kolli Professor Majlinda Lako Professor Francisco Figueiredo Dr Sajjad Ahmad	Loss of corneal epithelial stem cell properties in outgrowths from human limbal explants cultured on intact amniotic membrane	2008
Petra Stojkovic Professor Lyle Armstrong Professor Majlinda Lako Professor Miodrag Stojkovic	Non-invasive Imaging of Stem Cells by Scanning Ion Conductance Microscopy: Future Perspective	2008
Dr Rebecca Stewart Dr Chunbo Yang Dr George Anyfantis Dr Nicholas Hole Professor Tom Strachan et al.	Silencing of the expression of pluripotent driven-reporter genes stably transfected into human pluripotent cells	2008
Dr Hannah Gautrey Professor Majlinda Lako Dr Judith Hall Professor John Hesketh	Staufen1 is expressed in preimplantation mouse embryos and is required for embryonic stem cell differentiation	2008
Dr Irina Neganova Professor Majlinda Lako	Cell cycle regulation in human embryonic stem cells	2007
Professor Majlinda Lako	Characterization of human embryonic stem cell lines by the International Stem Cell Initiative	2007
Dr Sajjad Ahmad Dr Rebecca Stewart Sun Yung Sai Kolli Professor Lyle Armstrong et al.	Differentiation of human embryonic stem cells into corneal epithelial-like cells by in vitro replication of the corneal epithelial stem cell niche	2007
Dr Meenakshi Choudhary Petra Stojkovic Dr Louise Hyslop Dr George Anyfantis Professor Mary Herbert et al.	Putative role of hyaluronan and its related genes, HAS2 and RHAMM, in human early preimplantation embryogenesis and embryonic stem cell characterization	2007
Dr Sajjad Ahmad Professor Francisco Figueiredo Professor Majlinda Lako	Corneal epithelial stem cells: characterization, culture and transplantation	2006
Petra Stojkovic Professor Lyle Armstrong Professor Majlinda Lako Professor Miodrag Stojkovic	Derivation of human embryonic stem cells from developing and arrested embryos	2006
Professor Lyle Armstrong Professor Majlinda Lako Professor Miodrag Stojkovic	Epigenetic modification is central to genome reprogramming in somatic cell nuclear transfer	2006
Dr Graham Holliman Dr Ali Aldibbiat Dr Susan Campbell Professor Derek Manas Professor Majlinda Lako et al.	Expression of the pluripotent stem cell marker OCT-4 in normal adult human pancreas	2006
Dr Rebecca Stewart Professor Miodrag Stojkovic Professor Majlinda Lako	Mechanisms of self-renewal in human embryonic stem cells	2006
Professor Lyle Armstrong Professor Majlinda Lako	The future of human nuclear transfer?	2006
Professor Lyle Armstrong Dr Owen Hughes Sun Yung Dr Louise Hyslop Dr Rebecca Stewart et al.	The role of PI3K/AKT, MAPK/ERK and NFκβ signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis	2006
Petra Stojkovic Professor Majlinda Lako Dr Rebecca Stewart Professor Lyle Armstrong Jerome Evans et al.	An autogeneic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells	2005
Petra Stojkovic Professor Majlinda Lako Dr Rebecca Stewart Professor Lyle Armstrong Professor Mary Herbert et al.	An Autogeneic Feeder Cell System That Efficiently Supports Growth of Undifferentiated Human Embryonic Stem Cells	2005
Professor Miodrag Stojkovic Petra Stojkovic Vanessa Hall Professor Lyle Armstrong Professor Mary Herbert et al.	Derivation of a human blastocyst after heterologous nuclear transfer to donated oocytes	2005
Dr Louise Hyslop Professor Miodrag Stojkovic Professor Lyle Armstrong Theresia Walter Petra Stojkovic et al.	Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages	2005
Petra Stojkovic Professor Majlinda Lako Professor Lyle Armstrong Professor Miodrag Stojkovic	Human embryonic stem cells express markers of pluripotency and differentiate under long-term in vitro growth conditions	2005
Dr Louise Hyslop Professor Lyle Armstrong Professor Miodrag Stojkovic Professor Majlinda Lako	Human embryonic stem cells: Biology and clinical implications	2005
Petra Stojkovic Professor Majlinda Lako Professor Lyle Armstrong Jerome Evans Professor Miodrag Stojkovic et al.	Human-serum matrix supports undifferentiated growth of human embryonic stem cells	2005
Professor Majlinda Lako Professor Miodrag Stojkovic	In search of the best candidate for regeneration of ischemic tissues: are embryonic/fetal stem cells more advantageous than adult counterparts?	2005
Professor Majlinda Lako Professor Miodrag Stojkovic	In search of the best candidate for regeneration of ischemic tissues: Are embryonic/fetal stem cells more advantageous than adult counterparts?	2005
Dr Rebecca Stewart Professor Majlinda Lako	Neural development by transplanted human embryonal carcinoma stem cells expressing green fluorescent protein	2005
Professor Lyle Armstrong Dr Gabriele Saretzki Dr Heiko Peters Ilka Wappler Dr Nicholas Hole et al.	Overexpression of telomerase confers growth advantage, stress resistance, and enhanced differentiation of ESCs toward the hematopoietic lineage	2005
Dr Rebecca Stewart Professor Miodrag Stojkovic Professor Majlinda Lako	Signalling pathways in human ES cells	2005
Dr Sajjad Ahmad Professor Lyle Armstrong Professor Miodrag Stojkovic Ian Dimmick Dr Louise Hyslop et al.	The identification and characterisation of human corneal epithelial progenitors on the basis of high aldehyde dehydrogenase activity	2005
Professor Lyle Armstrong Professor Majlinda Lako Dr Nicholas Hole	A role for nucleoprotein Zap3 in the reduction of telomerase activity during embryonic stem cell differentiation	2004
Professor Lyle Armstrong Professor Majlinda Lako Dr Gabriele Saretzki Dr Nicholas Hole	A role for nucleoprotein Zap3 in the reduction of telomerase activity during embryonic stem cell differentiation	2004
Professor Miodrag Stojkovic Professor Majlinda Lako Petra Stojkovic Dr Rebecca Stewart Professor Lyle Armstrong et al.	Derivation of human embryonic stem cells from day-8 blastocysts recovered after three-step in vitro culture	2004
Professor Miodrag Stojkovic Professor Majlinda Lako Professor Tom Strachan Professor Alison Murdoch	Derivation, growth and applications of human embryonic stem cells	2004
Dr Sajjad Ahmad Dr Louise Hyslop Professor Colin Jahoda Professor Tom Strachan Professor Majlinda Lako et al.	From embryo to eye - Human embryonic stem cell markers OCT-4 and NANOG are localised to adult limbal epithelium	2004
Dr Rebecca Stewart Professor Majlinda Lako	Human embryonal carcinoma stem cells expressing green fluorescent protein form functioning neurons in vitro: A research tool for co-culture studies	2004
Dr Susan Campbell Professor Majlinda Lako	PDCD4 is a novel gene that is upreglated during pancreatic islet neogenesis, GLP-1 stimulation of whole islets and differentiation of embryonic stem cells to a beta cell phenotype	2004
Professor Lyle Armstrong Professor Miodrag Stojkovic Ian Dimmick Dr Sajjad Ahmad Petra Stojkovic et al.	Phenotypic characterization of murine primitive hematopoietic progenitor cells isolated on basis of aldehyde dehydrogenase activity	2004
Dr Susan Campbell Professor Lyle Armstrong Dr Nicholas Hole Professor Majlinda Lako	Programmed cell death gene 4 (PDCD4): A novel gene upregulated during islet neogenesis and embryonic stem cell differentiation	2004
Dr Gabriele Saretzki Professor Lyle Armstrong Alan Leake Professor Majlinda Lako Professor Thomas von Zglinicki et al.	Stress defense in murine embryonic stem cells is superior to that of various differentiated murine cells	2004
Professor Majlinda Lako Professor Lyle Armstrong Paul Cairns Dr Simon Harris Dr Nicholas Hole et al.	Hair follicle dermal cells repopulate the mouse haematopoietic system	2002
Professor Majlinda Lako Emerita Professor Susan Lindsay Paul Cairns Professor Lyle Armstrong Dr Nicholas Hole et al.	Characterisation of Wnt gene expression during the differentiation of murine embryonic stem cells in vitro: Role of Wnt3 in enhancing haematopoietic differentiation	2001
Professor Lyle Armstrong Professor Majlinda Lako Paul Cairns	mTert expression correlates with telomerase activity during the differentiation of murine embryonic stem cells	2000
Professor Majlinda Lako Dr Nicholas Hole	Searching the unknown with gene trapping	2000
Professor Majlinda Lako Professor Tom Strachan	Mutation screening in British 21-hydroxylase deficiency families and development of novel microsatellite based approaches to prenatal diagnosis	1999