Publications by Professor Christopher Ward - ePrints

Browsing publications by Professor Christopher Ward.

Newcastle Authors	Title	Year
Professor Christopher Ward	Air Pollution as a Risk Factor for Lung Cancer: Potential Mechanisms	2022
Professor Christopher Ward	Antimicrobial therapies for prevention of recurrent acute exacerbations of COPD (AECOPD): beyond the guidelines	2022
Dr Carlos Echevarria Dr Simon Doe Dr Malcolm Brodlie Professor Christopher Ward Dr Stephen Bourke et al.	Elexacaftor-Tezacaftor-Ivacaftor improve Gastro-Oesophageal reflux and Sinonasal symptoms in advanced cystic fibrosis	2022
Dr Hafez Al-momani Dr Christopher Stewart Rhys Jones Amaran Krishnan Dr Andrew Robertson et al.	Exposure to bile and gastric juice can impact the aerodigestive microbiome in people with cystic fibrosis	2022
Kyle Stanforth Dr Peter Chater Dr Iain Brownlee Dr Matthew Wilcox Professor Christopher Ward et al.	In vitro modelling of the mucosa of the oesophagus and upper digestive tract: narrative review	2022
Dr Iram Haq Dr Mike Althaus Dr Vinciane Saint-Criq Dr Bernard Verdon Dr Jen Townshend et al.	Clinical and molecular characterisation of the R751L-CFTR mutation	2021
Catherine Hatton Dr Rachel Botting Dr Maria Duenas Fadic Dr Iram Haq Dr Bernard Verdon et al.	Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2	2021
Dr Michael Mather Dr Bernard Verdon Dr Rachel Botting Justin Engelbert Livia Delpiano et al.	Development of a physiological model of human middle ear epithelium	2021
Dr Michael Mather Steven Powell Dr Ben Talks Professor Christopher Ward Professor Muzlifah Haniffa et al.	Dysregulation of immune response in otitis media	2021
Professor Christopher Ward	Eosinophilic Granulomatosis with Polyangiitis	2021
Professor Christopher Ward	Fully integrating pathophysiological insights in COPD: an updated working disease model to broaden therapeutic vision	2021
Abdullah Althuwaybi Maher Al Quaimi Amaran Krishnan Rhys Jones Professor Jeffrey Pearson et al.	Hospitalization outcomes for COVID-19 in patients with interstitial lung disease: A potential role for aerodigestive pathophysiology?	2021
Professor Christopher Ward	Mechanistic Insights on EMT and Smoking-Related COPD	2021
Nina Jordan Dr Sam Tingle Victoria Shuttleworth Katie Cooke Dr Rachael Redgrave et al.	MiR-126-3p Is Dynamically Regulated in Endothelial-to-Mesenchymal Transition during Fibrosis	2021
Professor Christopher Ward Amal Alamer	Bronchiectasis in the Elderly—a Disease That Has Not Gone Away	2020
Professor Christopher Ward Dr John Perry Amaran Krishnan Dr Rhys Jones Professor Jeffrey Pearson et al.	Clonally related viable nontuberculous mycobacteria in gastric juice and sputum in people with cystic fibrosis	2020
Dr Emily Mavin Dr Bernard Verdon Sean Carrie Dr Vinciane Saint-Criq Jason Powell et al.	Real-time measurement of cellular bioenergetics in fully differentiated human nasal epithelial 2 cells grown at air-liquid-interface	2020
Dr Aaron Ions Gardner Dr Iram Haq Professor John Simpson Dr Vinciane Saint-Criq Dr Bernard Verdon et al.	Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis	2020
Professor Christopher Ward	Stability of eosinophilic inflammation in COPD bronchial biopsies	2020
Jason Powell Dr Bernard Verdon Emerita Professor Janet Wilson Professor John Simpson Professor Jeffrey Pearson et al.	Establishment of an immortalized human subglottic epithelial cell line	2019
Professor Christopher Ward Dr Gerard Meachery Dr James Lordan Professor Andrew Fisher Emeritus Professor Nick Europe-Finner et al.	Long-term effect of azithromycin in bronchiolitis obliterans syndrome	2019
Dr Prosenjit Dutta Dr Wendy Funston Helen Mossop Vicky Ryan Rhys Jones et al.	Randomised, double-blind, placebo-controlled pilot trial of omeprazole in idiopathic pulmonary fibrosis	2019
Dr Vinciane Saint-Criq Dr Iram Haq Dr Aaron Ions Gardner Professor Christopher Ward Dr Malcolm Brodlie et al.	Real-Time, Semi-Automated Fluorescent Measurement of the Airway Surface Liquid pH of Primary Human Airway Epithelial Cells	2019
Professor Christopher Ward Dr Zelal Kharaba	Regarding epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux	2019
Professor Christopher Ward	The presence of Aspergillus fumigatus in asthmatic airways is not clearly related to clinical disease severity	2019
Shameem Sultanali Ladak Jason Powell Professor Andrew Fisher Professor Christopher Ward Professor Simi Ali et al.	The role of miR-200b-3p in modulating TGF-β1 induced injury in human bronchial epithelial cells	2019
Professor Christopher Ward Professor Jeffrey Pearson Dr James Lordan Professor Anthony De Soyza	A qualitative synthesis of gastro-oesophageal reflux in bronchiectasis: Current understanding and future risk	2018
Professor Christopher Ward Dr Robert Rutherford	Comorbidities and their impact	2018
Professor Christopher Ward	Epithelial mesenchymal transition (EMT), a spectrum of states: role in lung development, homeostasis and disease	2018
Jason Powell Dr James Garnett Dr Michael Mather Dr Faye Cooles Dr Bernard Verdon et al.	Excess Mucin Impairs Subglottic Epithelial Host Defense in Mechanically Ventilated Patients	2018
Professor Christopher Ward Rhys Jones Dr Melissa Friel	Pathophysiology in the Lung	2018
Dr Desmond Murphy Professor Christopher Ward Professor Jeffrey Pearson	Response	2018
Rhys Jones Amaran Krishnan Dr Malcolm Brodlie Professor Jeffrey Pearson Professor Stephen Bourke et al.	Risk factors for lung disease progression in children with cystic fibrosis	2018
Adil Aldhahrani Jason Powell Shameem Sultanali Ladak Dr Mohammed Ali Professor Simi Ali et al.	The Potential Role of Bile Acids in Acquired Laryngotracheal Stenosis	2018
Professor Christopher Ward	Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD)	2017
Professor Christopher Ward	Airway inflammation and inhaled corticosteroids in COPD.	2017
Zachary Shellman Adil Aldhahrani Dr Bernard Verdon Dr Michael Mather Professor Vinidh Paleri et al.	Bile acids: a potential role in the pathogenesis of pharyngeal malignancy	2017
Salam Ibrahim Mark Turner Dr Vinciane Saint-Criq Dr James Garnett Dr Iram Haq et al.	CK2 is a key regulator of SLC₄A2- mediated Cl-/HCO₃- exchange in human airway epithelia	2017
Adil Aldhahrani Dr Bernard Verdon Professor Christopher Ward Professor Jeffrey Pearson	Effects of Bile acids on Human Airway Epithelial Cells; implications for aerodigestive diseases	2017
Professor Christopher Ward	Epithelial mesenchymal transition (EMT) and non-small cell lung cancer (NSCLC): a mutual association with airway disease	2017
Professor Christopher Ward	Epithelial-mesenchymal transition: A necessary new therapeutic target in chronic obstructive pulmonary disease?	2017
Dr Hafez Al-momani Rhys Jones Professor Stephen Bourke Dr Simon Doe Dr John Perry et al.	Nontuberculous mycobacteria in gastrostomy fed patients with cystic fibrosis	2017
Professor Christopher Ward	Profiling cellular and inflammatory changes in the airway wall of mild to moderate COPD	2017
Professor Christopher Ward Professor Jeffrey Pearson	The potential role of aspiration in the asthmatic airway	2017
Professor Christopher Ward	Transforming growth factor (TGF) ß1 and Smad signaling pathways: A likely key to EMT-associated COPD pathogenesis	2017
Dr Aaron Ions Gardner Professor Christopher Ward Dr Malcolm Brodlie	β1-integrin accumulates in cystic fibrosis luminal airway epithelial membranes and decreases sphingosine promoting bacterial infections	2017
Professor Christopher Ward	β-catenin, Twist and Snail: Transcriptional regulation of EMT in smokers and COPD, and relation to airflow obstruction	2017
Professor Christopher Ward	A Study To Define The Microbiome Of The Asthmatic Airway	2016
Dr Iram Haq Dr Michael Gray Dr James Garnett Professor Christopher Ward Dr Malcolm Brodlie et al.	Airway surface liquid homeostasis in cystic fibrosis: pathophysiology and therapeutic targets	2016
Professor Anthony De Soyza Professor Christopher Ward	Comorbidities and the risk of mortality in patients with bronchiectasis: an international multicentre cohort study	2016
Rhys Jones Professor Jeffrey Pearson Professor Christopher Ward	Functional Dyspepsia	2016
Mark Turner Dr Vinciane Saint-Criq Waseema Patel Salam Ibrahim Dr Burns Verdon et al.	Hypercapnia Modulates cAMP Signalling and Cystic Fibrosis Transmembrane Conductance Regulator-dependent Anion and Fluid Secretion in Airway Epithelia	2016
Dr James Garnett Dr Georgina Carr Jason Powell Dr Malcolm Brodlie Professor Christopher Ward et al.	Hyperglycaemia and Pseudomonas aeruginosa acidify cystic fibrosis airway surface liquid by elevating epithelial monocarboxylate transporter 2 dependent lactate-H⁺ secretion	2016
Professor Christopher Ward Emeritus Professor Nick Europe-Finner Dr Malcolm Brodlie	IL-22 exacerbates weight loss in a murine model of chronic pulmonary Pseudomonas aeruginosa infection	2016
Professor Christopher Ward	Inhaled corticosteroid normalizes some but not all airway vascular remodeling in COPD	2016
Dr Hafez Al-momani Dr Christopher Stewart Rhys Jones Amaran Krishnan Dr Andrew Robertson et al.	Microbiological profiles of sputum and gastric juice aspirates in Cystic Fibrosis patients	2016
Shameem Sultanali Ladak Professor Christopher Ward Professor Simi Ali	MiRNA-200b Inhibits Epithelial-Mesenchymal Transition in TGF-b1 Induced Human Bronchial Epithelial Cells.	2016
Professor Christopher Ward	Mucosal Cytokines In Asthmatic Bronchoalveolar Lavage (bal) Fluid Reflect Systemic Inflammation And Disease Severity	2016
Professor Christopher Ward Professor Anthony De Soyza	Multidimensional severity assessment in bronchiectasis: an analysis of seven European cohorts	2016
Professor Christopher Ward Professor Anthony De Soyza	Multidimensional Severity Assessment in Bronchiectasis-An Analysis of 7 European Cohorts	2016
Christopher Cole Dr Sonya Carnell Kasim Jiwa Dr Jodie Birch Dr Katy Hester et al.	Neutrophil vascular endothelial growth factor (VEGF) as a driving force for angiogenesis in bronchiectasis?	2016
Dr Jodie Birch Stella Victorelli Rhys Anderson Kasim Jiwa Dr Elizabeth Moisey et al.	Telomere Dysfunction and Senescence-associated Pathways in Bronchiectasis	2016
Professor Christopher Ward Professor Jeffrey Pearson	The Potential Role of Aspiration in the Asthmatic Airway Response	2016
Shameem Ladak Professor Christopher Ward Professor Simi Ali	The potential role of microRNAs in lung allograft rejection	2016
Jason Powell Dr James Garnett Dr Bernard Verdon Emerita Professor Janet Wilson Professor Jeffrey Pearson et al.	A Human in Vitro Model of the Subglottic Airway	2015
Emeritus Professor Nick Europe-Finner Vicky Ryan Therese Small Dr James Lordan Professor Andrew Fisher et al.	A randomised controlled trial of azithromycin therapy in Bronchiolitis Obliterans Syndrome (BOS) post lung transplantation	2015
Dr James Garnett Dr Michael Gray Dr Malcolm Brodlie Professor Christopher Ward	Airway epithelial cells secrete bicarbonate in response to acidic by-products of pseudomonas aeruginosa metabolism	2015
Professor Anthony De Soyza Dr James Lordan Professor Jeffrey Pearson Professor Christopher Ward	Azithromycin Attenuates Release Of Bile Acid-Mediated Neutrophilic And Remodeling Factors From Human Bronchial Epithelial Cells	2015
Professor Anthony De Soyza Dr James Lordan June Pearson Professor Christopher Ward	Azithromycin Attenuates Release of Bile Acid-Mediated Neutrophilic and Remodelling Factors from Human Bronchial Epithelial Cells	2015
Dr Malcolm Brodlie Ali Aseeri Dr James Lordan Dr Andrew Robertson Dr Michael McKean et al.	Bile acid aspiration in people with cystic fibrosis before and after lung transplantation	2015
Professor Anthony De Soyza Dr James Lordan Professor Jeffrey Pearson Professor Christopher Ward	Bile Acids Cause Direct Inflammation And Injury And Worsen Acid Induced Injury In The Pulmonary Epithelium	2015
Professor Anthony De Soyza Dr James Lordan Professor Jeffrey Pearson Professor Christopher Ward	Bile Acids Cause Direct Inflammation and Injury and Worsen Acid Induced Injury in the Pulmonary Epithelium	2015
Professor Christopher Ward	Describing the Microbiome in the Asthmatic Airway	2015
Professor Christopher Ward	Epithelial mesenchymal transition in smokers: large versus small airways and relation to airflow obstruction	2015
Professor Christopher Ward	Hiatal hernias are correlated with increased severity of non-cystic fibrosis bronchiectasis	2015
Shameem Sultanali Ladak Professor Christopher Ward Professor Simi Ali	MicroRNA-200b represses TGF-β1 induced EMT in BEAS-2B and primary bronchial epithelial cells	2015
Professor Christopher Ward	'To measure is to know' (Lord Kelvin)	2015
Professor Christopher Ward	A randomized controlled trial of inhaled corticosteroids (ICS) on markers of epithelial-mesenchymal transition (EMT) in large airway samples in COPD: an exploratory proof of concept study	2014
Rhys Jones Amaran Krishnan Professor Jeffrey Pearson Professor John Simpson Professor Michael Griffin et al.	Characterisation of Reflux and Aspiration in Idiopathic Pulmonary Fibrosis; An Integrated Approach	2014
Professor Christopher Ward	Importance of epithelial mesenchymal transition (EMT) in COPD and asthma	2014
Dr Ali Anwar Professor Anthony De Soyza Dr Sylvia Worthy Emeritus Professor Nick Europe-Finner Dr James Lordan et al.	Lack of association between KIR and HLA-C type and susceptibility to idiopathic bronchiectasis	2014
Monika Suwara Dr Bart Vanaudenaerde Dr Nicola Green Professor Christopher Ward Dr Lee Borthwick et al.	Mechanistic differences between phenotypes of chronic lung allograft dysfunction after lung transplantation	2014
Gemma Crossfield Amaran Krishnan Dr Iain Brownlee Professor Christopher Ward Professor Jeffrey Pearson et al.	Overweight and obesity challenges in the Cystic Fibrosis population - a need for revision in nutritional advice?	2014
Shameem Sultanali Ladak Professor Simi Ali Professor Christopher Ward	The potential role of miRNA-200b in the development of Bronchiolitis obliterans syndrome	2014
Dr Shruti Parikh Dr Andrew Robertson Dr Malcolm Brodlie Emeritus Professor Nick Europe-Finner Professor Christopher Ward et al.	Are the enzymatic methods currently being used to measure bronchoalveolar lavage bile salt levels fit for purpose?	2013
Professor Michael Griffin Dr Andrew Robertson Dr Iain Brownlee Rachel Stovold Dr Malcolm Brodlie et al.	Aspiration and Allograft Injury Secondary to Gastroesophageal Reflux Occur in the Immediate Post-Lung Transplantation Period (Prospective Clinical Trial)	2013
Dr James Garnett Dr Michael Gray Dr Malcolm Brodlie Professor Christopher Ward Erin Baker et al.	Elevated Paracellular Glucose Flux across Cystic Fibrosis Airway Epithelial Monolayers Is an Important Factor for Pseudomonas aeruginosa Growth	2013
Amaran Krishnan Dr Malcolm Brodlie Emeritus Professor Nick Europe-Finner Professor Michael Griffin Dr Ian Forrest et al.	Identical Biofilm Forming Strains of Pseudomonas aeruginosa Occur in Lung Allograft BAL and Gastric Juice from CF Patients with Gastro Oesophageal Reflux	2013
Professor Christopher Ward Professor Simi Ali	Identification of biomolecular marker of chronic lung allograft rejection	2013
Rhys Jones Amaran Krishnan Dr Ian Forrest Professor Christopher Ward Arul Immanuel et al.	Initial Experience of an Aerodigestive Multidisciplinary Team	2013
Professor Christopher Ward Dr James Lordan Dr Robert Rutherford	Non-cystic fibrosis bronchiectasis	2013
Dr Malcolm Brodlie Professor Christopher Ward Emeritus Professor Nick Europe-Finner	Novel T helper cell responses against Pseudomonas aeruginosa in healthy individuals and patients with cystic fibrosis	2013
Gemma Crossfield Vicki Strugala Professor Christopher Ward Professor Jeffrey Pearson	Pepsin detection despite the use of acid suppressant medication in patients with airway reflux related chronic cough	2013
Dr Ali Anwar Dr Sylvia Worthy Professor Stephen Bourke Dr James Lordan Emeritus Professor Nick Europe-Finner et al.	Phenotyping adults with non-cystic fibrosis bronchiectasis: A prospective observational cohort study	2013
Professor Christopher Ward	Recent advances in understanding inflammation and remodeling in the airways in chronic obstructive pulmonary disease	2013
Professor Christopher Ward	Recent advances in understanding inflammation and remodeling in the airways in chronic obstructive pulmonary disease	2013
Jen Birch Dr Gavin Johnson Professor Christopher Ward Dr John Taylor Emeritus Professor Nick Europe-Finner et al.	Small Airway Epithelial Cell Senescence Present in COPD and Bronchiectasis?	2013
Dr Lee Borthwick Emeritus Professor Nick Europe-Finner Dr Rahul Mahida Andrew Walker Aaron Gardner et al.	TNFα From Classically Activated Macrophages Accentuates Epithelial to Mesenchymal Transition in Obliterative Bronchiolitis	2013
Emeritus Professor Nick Europe-Finner Therese Small Vicky Ryan Dr James Lordan Professor Andrew Fisher et al.	A Randomised Controlled Trial of Azithromycin Therapy in Bronchiolitis Obliterans Syndrome (BOS) Post Lung Transplantation	2012
Dr Andrew Robertson Amaran Krishnan Professor Christopher Ward Professor Jeffrey Pearson Therese Small et al.	Anti-reflux surgery in lung transplant recipients: outcomes and effects on quality of life	2012
Ali Aseeri Dr Malcolm Brodlie Dr James Lordan Emeritus Professor Nick Europe-Finner Professor Jeffrey Pearson et al.	Bile Acids Are Present in the Lower Airways of People with Cystic Fibrosis	2012
Rachel Stovold Professor Jeffrey Pearson Professor Christopher Ward	Chronic Cough: Relationship Between Microaspiration, Gastroesophageal Reflux, and Cough Frequency	2012
Professor Christopher Ward	Epithelial Mesenchymal Transition (EMT) in Chronic Obstructive Pulmonary Disease (COPD) Airways is Attenuated by Inhaled Corticosteroids (ICS)	2012
Dr Malcolm Brodlie Emeritus Professor Nick Europe-Finner Dr James Lordan Professor Christopher Ward	Interleukin-17 and Cystic Fibrosis Lung Disease	2012
Dr Aaron Ions Gardner Professor Andrew Fisher Christine Richter Grace Johnson Dr Elizabeth Moisey et al.	The Critical Role of TAK1 in Accentuated Epithelial to Mesenchymal Transition in Obliterative Bronchiolitis after Lung Transplantation	2012
Dr Lee Borthwick Dr John Perry Dr Malcolm Brodlie Professor Christopher Ward Katherine Gould et al.	Pseudomonas aeruginosa accentuates epithelial-to-mesenchymal transition in the airway	2011
Dr Malcolm Brodlie Dr James Lordan Professor Christopher Ward	Can cells other than Th17 lymphocytes be important sources of IL-17 in the lungs?	2011
Dr Malcolm Brodlie Dr James Lordan Professor Christopher Ward	Ceramide and cystic fibrosis lung disease	2011
Professor Christopher Ward	Infection and remodelling: a 21st century model of bronchiectasis?	2011
Dr Malcolm Brodlie Dr Michael McKean Dr Amy Anderson Professor Catharien Hilkens Professor Andrew Fisher et al.	Raised interleukin-17 is immunolocalised to neutrophils in cystic fibrosis lung disease	2011
Professor Christopher Ward	Assessment of airway inflammation using sputum, BAL, and endobronchial biopsies in current and ex-smokers with established COPD	2010
Dr Malcolm Brodlie Dr Michael McKean Dr Joseph Gray Professor Andrew Fisher Emeritus Professor Nick Europe-Finner et al.	Ceramide is Increased in the Lower Airway Epithelium of People with Advanced Cystic Fibrosis Lung Disease	2010
Dr Ali Anwar Professor Stephen Bourke Dr Peter Middleton Professor Christopher Ward Dr Robert Rutherford et al.	Efficacy of nebulised colomycin in patients with non-cystic fibrosis bronchiectasis colonised with Pseudomonas aeruginosa	2010
Dr Iain Brownlee Ali Aseeri Professor Christopher Ward Professor Jeffrey Pearson	From gastric aspiration to airway inflammation	2010
Dr Lee Borthwick Marta Gorowiec Dr Malcolm Brodlie Professor Christopher Ward Dr James Lordan et al.	Inflammation and Epithelial to Mesenchymal Transition in Lung Transplant Recipients: Role in Dysregulated Epithelial Wound Repair	2010
Dr Andrew Robertson Professor Christopher Ward Therese Small Dr James Lordan Professor Andrew Fisher et al.	Longitudinal changes in gastro-oesophageal reflux from three months to six months post lung transplantation	2010
Dr Andrew Robertson Professor Christopher Ward Professor Jeffrey Pearson Emeritus Professor Nick Europe-Finner Professor John Dark et al.	Lung Transplantation, Gastroesophageal Reflux, and Fundoplication	2010
Dr Ian Forrest Professor Christopher Ward	Macrolide antibiotics and the airway: antibiotic or non-antibiotic effects?	2010
Dr Malcolm Brodlie Dr Michael McKean Dr John Perry Dr Burns Verdon Dr Michael Gray et al.	Primary bronchial epithelial cell culture from explanted cystic fibrosis lungs	2010
Dr Don Reid Professor Christopher Ward	Reticular basement membrane fragmentation and potential epithelial mesenchymal transition is exaggerated in the airways of smokers with chronic obstructive pulmonary disease	2010
Professor Christopher Ward Vicky Ryan Professor Jeffrey Pearson	Susceptibility to Exacerbation in COPD	2010
Dr Lee Borthwick Dr Malcolm Brodlie Professor Christopher Ward Dr John Perry Emeritus Professor Nick Europe-Finner et al.	The M1 macrophage phenotype accentuates TGF-beta 1 driven epithelial to mesenchymal transition (EMT) via the secretion of TNF alpha	2010
Dr Andrew Robertson Dr Jonathan Shenfine Professor Christopher Ward Professor Jeffrey Pearson Professor John Dark et al.	A Call for Standardization of Antireflux Surgery in the Lung Transplantation Population	2009
Dr Malcolm Brodlie Professor Catharien Hilkens Professor Christopher Ward	Airway epithelial cells as guardians of immune homeostasis?	2009
Dr Andrew Robertson Professor Michael Griffin Professor Christopher Ward Professor Jeffrey Pearson Professor John Dark et al.	Aspiration in the Immediate Post Lung Transplantation Period	2009
Dr Andrew Robertson Professor Christopher Ward Professor Jeffrey Pearson Professor Andrew Fisher Dr James Lordan et al.	Aspiration Secondary to Gastro-Oesophageal Reflux but not Duodenal Reflux Occurs in the Immediate Post Lung Transplantation Period	2009
Dr Ian Forrest Professor Christopher Ward Vicky Ryan Dr Gavin Johnson Dr James Lordan et al.	Bronchalveolar Lavage Neutrophilia and MMP-9 at 3 Months Post Lung Transplantation May Predict the Development of BOS	2009
Professor Christopher Ward Julie Diboll Professor Andrew Fisher Dr Malcolm Brodlie Dr James Lordan et al.	Bronchial epithelial cells cultured from clinically stable lung allograft patients promote the development of macrophages from monocytes rather than dendritic cells	2009
Dr Malcolm Brodlie Dr Michael McKean Professor Andrew Fisher Emeritus Professor Nick Europe-Finner Dr James Lordan et al.	Ceramide is increased and associated with neutrophilic inflammation in the lower airway epithelium of people with cystic fibrosis	2009
Dr Lee Borthwick Dr Sean Parker Kate Brougham Marta Gorowiec Professor Christopher Ward et al.	Epithelial to mesenchymal transition (EMT) and airway remodelling after human lung transplantation	2009
Professor Christopher Ward Professor Jeffrey Pearson Therese Small Dr James Lordan Professor Andrew Fisher et al.	Longitudinal changes in gastro-oesophageal reflux from 3 months to 6 months after lung transplantation	2009
Dr Lee Borthwick Dr Malcolm Brodlie Professor Christopher Ward Dr James Lordan Professor John Kirby et al.	Pro-inflammatory Cytokines IL-1 beta and TNT alpha, but Not IL-8, Cause Aberrant Lung Epithelial Wound Repair Via TGF-beta 1 Driven Epithelial to Mesenchymal Transition (EMT)	2009
Dr Malcolm Brodlie Dr Michael McKean Professor Andrew Fisher Emeritus Professor Nick Europe-Finner Dr James Lordan et al.	Reticular basement membrane thickening in end-stage cystic fibrosis lung disease	2009
Dr Andrew Robertson Professor Michael Griffin Professor Jeffrey Pearson Dr Ian Forrest Professor John Dark et al.	Targeting Allograft Injury and Inflammation in the Management of Post-Lung Transplant Bronchiolitis Obliterans Syndrome	2009
Rachel Stovold Dr Ian Forrest Dr James Lordan Professor Andrew Fisher Professor John Dark et al.	Temporal Patterns of Lung Pepsin Levels in Allografts Suggest Aspiration Is an Ongoing Injury, Which Can Occur Early Following Lung Transplantation	2009
Dr Sean Parker Dr Lee Borthwick Professor Christopher Ward Dr James Lordan Emeritus Professor Nick Europe-Finner et al.	Airway epithelial cell senescence in the lung allograft	2008
Professor Christopher Ward	Angiogenesis: A potentially critical part of remodelling in chronic airway diseases?	2008
Dr Rachel Anderson Professor Christopher Ward Dr Ian Forrest Dr James Lordan Emeritus Professor Nick Europe-Finner et al.	Antimicrobial Peptides in Lung Transplant Recipients with Bronchiolitis Obliterans Syndrome	2008
Adillah Binti Yusof Dr Ian Forrest Emeritus Professor Nick Europe-Finner Therese Small Debra Jones et al.	Azithromycin attenuates effects of lipopolysaccharide on lung allograft bronchial epithelial cells	2008
Dr Ian Forrest Emeritus Professor Nick Europe-Finner Dr Gavin Johnson Therese Small Professor Andrew Fisher et al.	Azithromycin attenuates lipopolysaccharide-mediated release of interleukin-8 and GM-CSF from primary bronchial epithelial cells derived from stable lung transplant recipients	2008
Professor Christopher Ward	Bronchodilator reversibility, airway eosinophilia and anti-inflammatory effects of inhaled fluticasone in COPD are not related	2008
Rachel Stovold Emeritus Professor Nick Europe-Finner Professor Andrew Fisher Dr James Lordan Professor Jeffrey Pearson et al.	Does pepsin in gastric juice aspirated into the lung allograft stimulate mucus hypersecretion?	2008
Dr Ali Anwar Professor Stephen Bourke Dr Peter Middleton Professor Christopher Ward Dr Robert Rutherford et al.	Effects of long-term low-dose azithromycin in patients with non-CF bronchiectasis	2008
Professor Christopher Ward	Innate immune activation in neutrophilic asthma	2008
Rachel Stovold Dr Ian Forrest Dr James Lordan Professor Andrew Fisher Emeritus Professor Nick Europe-Finner et al.	Longitudinal assessment of pepsin levels in lung allografts suggests aspiration is an ongoing injury, which can occur early following lung transplantation	2008
Marta Gorowiec Dr Lee Borthwick Marcin Pekalski Dr James Lordan Emeritus Professor Nick Europe-Finner et al.	Oxidative stress induces epithelial to mesenchymal transition in human lung epithelial cells through transforming groeth factor beta and integrin beta6-dependent mechanism	2008
Dr Lee Borthwick Kate Brougham Professor Christopher Ward Dr James Lordan Professor John Kirby et al.	Pro-inflammatory cytokines dysregulate lung epithelial wound repair via epithelial to mesenchymal transition	2008
Dr Andrew Robertson Professor Michael Griffin Professor Christopher Ward Professor Jeffrey Pearson Anne Bredenoord et al.	Qualitative and quantitative assessments of aspiration in the immediate post-lung transplantation period	2008
Rachel Stovold Professor Jeffrey Pearson Professor Christopher Ward	Relationships between micro-aspiration, gastro-oesophageal reflux and cough in chronic cough subjects	2008
Emeritus Professor Mike Sir Michael Rawlins Dr Ian Forrest Emeritus Professor Nick Europe-Finner Therese Small Debra Jones et al.	Simvastatin attenuates release of neutrophilic and remodeling factors from primary bronchial epithelial cells derived from stable lung transplant recipients	2008
Dr Ian Forrest Emeritus Professor Nick Europe-Finner Therese Small Professor Andrew Fisher Emeritus Professor Tim Cawston et al.	Simvastatin potentially decreases neutrophilic inflammation and remodelling in the transplanted airway	2008
Dr Malcolm Brodlie Dr Michael McKean Dr John Perry Anne Nicholson Professor Jeffrey Pearson et al.	The culture of primary bronchial epithelial cells from the lungs of people with cystic fibrosis removed at the time of transplantation: a model to study cystic fibrosis lung disease	2008
Dr Lee Borthwick Sally Maloney Dr Rachel Anderson Professor Christopher Ward Dr James Lordan et al.	Transforming growth factor beta 1 suppresses secretory leucoprotease inhibitor release in response to infection in lung epithelial cells	2008
Dr Lee Borthwick Dr Sean Parker Marta Gorowiec Professor Christopher Ward Dr James Lordan et al.	Tumour necrosis factor-α accentuates transforming growth factor-β driven epithelial to mesenchymal transition (EMT) in airway epithelial cells from lung transplant recipients	2008
Professor Christopher Ward	Vascular remodelling in asthma	2008
Professor Christopher Ward	Airway cell and cytokine changes in early asthma deterioration after inhaled corticosteroid reduction	2007
Dr Laura Mackay Professor Christopher Ward Dr James Lordan Professor Andrew Fisher Emeritus Professor Nick Europe-Finner et al.	Alveolar septae in severe end-stage emphysema show morphological evidence of dysregulated mesenchymal cell proliferation and loss of microvascularity	2007
Dr Ian Forrest Professor Christopher Ward Emeritus Professor Nick Europe-Finner Debra Jones Professor Andrew Fisher et al.	Effect of azithromycin on primary bronchial epithelial cells derived from stable lung allografts	2007
Professor Christopher Ward	Effects of inhaled fluticasone on angiogenesis and vascular endothelial growth factor in asthma	2007
Professor Christopher Ward	Nonpharmacological and pharmacological interventions to prevent or reduce airway remodelling	2007
Marta Gorowiec Dr Sean Parker Dr Lee Borthwick Professor Christopher Ward Dr James Lordan et al.	Oxidative stress increases transforming growth factor-beta expression and drives epithelial to mesenchymal transition in human lung epithelial cells	2007
Rachel Stovold Dr Ian Forrest Emeritus Professor Nick Europe-Finner Professor John Dark Professor Jeffrey Pearson et al.	Pepsin, a biomarker of gastric aspiration in lung allografts: A putative association with rejection	2007
Rachel Stovold Dr Ian Forrest Emeritus Professor Nick Europe-Finner Julie Smith Professor John Dark et al.	Pepsin, a biomarker of gastric aspiration in lung allografts: a putative association with rejection	2007
Dr Sean Parker Professor Christopher Ward Dr James Lordan Emeritus Professor Nick Europe-Finner Dr Gabriele Saretzki et al.	Stress-induced premature senescence in airway epithelium and accelerated lung allograft aging	2007
Dr Sean Parker Marta Gorowiec Dr Lee Borthwick Dr James Lordan Professor Christopher Ward et al.	Transforming growth factor beta (TGF beta) induces cellular senescence in primary bronchial epithelial cells: A possible role in airway remodelling	2007
Professor Barbara Hanratty Professor Carl May Professor Christopher Ward	Doctor's understanding of palliative care	2006
Dr Lee Borthwick Professor Christopher Ward Dr James Lordan Emeritus Professor Nick Europe-Finner Professor Andrew Fisher et al.	Epithelial mesencymal transition occurs in primary airway epithelial cells in response to transforming growth factor-beta and epidermal growth factor	2006
Rachel Stovold Dr Ian Forrest Dr Desmond Murphy Emeritus Professor Nick Europe-Finner Professor Andrew Fisher et al.	Evidence of increased gastric aspiration in acute lung allograft rejection	2006
Dr Ian Forrest Professor Christopher Ward Dr Desmond Murphy David Jones Dr James Lordan et al.	Hepatocyte growth factor - A link between neutrophilic inflammation and BOS?	2006
Professor Christopher Ward	Increased vascular endothelial growth factor and receptors - Relationship to angiogenesis in asthma	2006
Dr Lee Borthwick Dr Sean Parker Professor Christopher Ward Emeritus Professor Nick Europe-Finner Dr James Lordan et al.	Oxidative stress induces epithelial to mesenchymal transition in bronchial epithelial cells: A possible role in airway remodelling	2006
Dr Sean Parker Professor Christopher Ward Dr Fiona Black Dr James Lordan Emeritus Professor Nick Europe-Finner et al.	Premature senescence of airway epithelial cells: A possible role in airway remodelling after human lung transplantation	2006
Professor Christopher Ward Dr Ian Forrest Professor David Jones Dr Gary Pritchard Rachel Stovold et al.	The phosphodiesterase type IV (PDE IV) inhibitor cilomilast decreases pro-inflammatory cytokine production from primary bronchial epithelial cells derived from lung transplant recipients	2006
Dr Desmond Murphy Professor Christopher Ward David Jones Rachel Stovold Professor Andrew Fisher et al.	The phosphodiesterase type IV inhibitor cilomilast decreases pro-inflammatory cytokine production from primary bronchial epithelial cells in lung transplantation patients	2006
Dr Lee Borthwick Professor Christopher Ward Dr James Lordan Emeritus Professor Nick Europe-Finner Professor Andrew Fisher et al.	Tumour necrosis factor-alpha accentuates transforming growth factor-beta driven epithelial to mesenchymal transition in lung epithelial cells	2006
Professor Christopher Ward Professor Anthony De Soyza Professor Andrew Fisher Emeritus Professor Nick Europe-Finner	A descriptive study of small airway reticular basement membrane thickening in clinically stable lung transplant recipients	2005
Professor Christopher Ward	Airway wall remodelling: The influence of corticosteroids	2005
Professor Christopher Ward Suzanne Scorfield Phil Botha Professor John Dark Emeritus Professor Nick Europe-Finner et al.	Association between the genotype of the TNF locus and acute rejection following lung transplant	2005
Professor Christopher Ward Dr Robert Rutherford Professor Andrew Fisher Dr James Lordan Professor John Dark et al.	Azithromycin reverses airflow obstruction in established bronchiolitis obliterans syndrome	2005
Professor Christopher Ward Dr Ian Forrest Professor Andrew Fisher Dr James Lordan Emeritus Professor Nick Europe-Finner et al.	Azithromycin reverses airflow obstruction in established bronchiolitis obliterans syndrome (BOS) following lung transplantation	2005
Professor Christopher Ward	Bronchial hyperresponsiveness and the bronchiolitis obliterans syndrome after lung transplantation	2005
Dr Ian Forrest Dr James Lordan Dr Gary Pritchard Professor David Jones Dr Helen Robertson et al.	Epithelial to mesenchymal transition in clinically stable lung transplant recipients	2005
Dr Lindsay Nicholson Professor Christopher Ward Professor John Dark Dr Peter Middleton Emeritus Professor Nick Europe-Finner et al.	Genetic polymorphisms and bronchiolitis obliterans syndrome post lung transplantation	2005
Professor Christopher Ward Dr Helen Robertson Dr Ian Forrest Dr James Lordan Denis Murphy et al.	Hypothesis: Epithelial-to-mesenchymal transition is a common cause of chronic allograft failure	2005
Professor Christopher Ward Vicky Ryan	Inter-relationships between airway inflammation, reticular basement membrane thickening and bronchial hyper-reactivity to methacholine in asthma; a systematic bronchoalveolar lavage and airway biopsy analysis	2005
Professor Christopher Ward	Longitudinal comparisons of lymphocytes and subtypes between airway wall and bronchoalveolar lavage after human lung transplantation	2005
Professor Christopher Ward Dr Ian Forrest Dr Iain Brownlee Professor Jeffrey Pearson Professor John Dark et al.	Pepsin like activity in bronchoalveolar lavage fluid is suggestive of gastric aspiration in lung allografts	2005
Professor Christopher Ward Dr Ian Forrest Dr Helen Robertson Emeritus Professor Tim Cawston Professor Andrew Fisher et al.	Phenotype of airway epithelial cells suggests epithelial to mesenchymal cell transition in clinically stable lung transplant recipients	2005
Dr Ian Forrest Dr Desmond Murphy Professor Christopher Ward David Jones Professor Kate Gould et al.	Primary airway epithelial cell culture from lung transplant recipients	2005
Dr Ian Forrest Professor Christopher Ward Emeritus Professor Nick Europe-Finner Professor Andrew Fisher Emeritus Professor Tim Cawston et al.	The potential role of interleukin-17 in airway inflammation and remodelling in post-transplant obliterative bronchiolitis	2005
Professor Bob Anderson Dr Ian Forrest Professor Christopher Ward Dr Gavin Johnson Dr James Lordan et al.	The pulmonary innate immune response to pseudomonas aeruginosa infection in human lung transplant recipients	2005
Professor Christopher Ward Dr Iain Brownlee Dr Ian Forrest Dr Thomas Ward Dr Desmond Murphy et al.	Clinically silent gastric aspiration is common in lung allografts	2004
Dr Ian Forrest Dr James Lordan Dr Helen Robertson Emeritus Professor Tim Cawston Professor John Dark et al.	Epithelial to mesenchymal transition in clinically stable lung transplantation	2004
Dr Ian Forrest Professor Christopher Ward Emeritus Professor Nick Europe-Finner Dr Peter Middleton	Genotypic risk factors for the development of the bronchiolitis oblitererans syndrome (BOS) after lung transplantation	2004
Dr Ian Forrest Professor Christopher Ward Emeritus Professor Tim Cawston Emeritus Professor Nick Europe-Finner Dr James Lordan et al.	IL-17 stimulates IL-8 release in primary epithelial cell cultures derived from lung allografts	2004
Dr Iain Brownlee Professor Christopher Ward Dr Ian Forrest Dr Gary Pritchard Professor John Dark et al.	Pepsin detection in the lungs of transplant patients: Evidence of gastric refluxate	2004
Professor Christopher Ward Professor Anthony De Soyza Professor Andrew Fisher Emeritus Professor Nick Europe-Finner	Reticular basement membrane thickening in airways of lung transplant recipients is not affected by inhaled corticosteroids	2004
Professor Christopher Ward	Exhaled nitric oxide continues to reflect airway hyperresponsiveness and disease activity in inhaled corticosteroid-treated adult asthmatic patients	2003
Professor Christopher Ward	Possible anti-inflammatory effect of salmeterol against interleukin-8 and neutrophil activation in asthma in vivo	2003
Professor Christopher Ward Dr Ian Forrest Professor Anthony De Soyza Professor Andrew Fisher Emeritus Professor Nick Europe-Finner et al.	Preliminary findings of quorum signal molecules in clinically stable lung allograft recipients	2003
Professor Christopher Ward	Revision of BTS guidelines for treatment of asthma [1] (multiple letters)	2003
Professor Christopher Ward Dr Ian Forrest Professor Anthony De Soyza Professor Andrew Fisher Emeritus Professor Nick Europe-Finner et al.	The presence of quorum-sensing signal molecules in clinically stable lung	2003
Professor Christopher Ward	Addition of inhaled corticosteroids to systemic immunosuppression after lung transplantation: a double-blind, placebo-controlled trial [see comment]	2002
Professor Christopher Ward	Airway inflammation, basement membrane thickening and bronchial hyperresponsiveness in asthma	2002
Professor Christopher Ward Dr Gary Pritchard Emeritus Professor Drew Rowan Emeritus Professor Tim Cawston Emeritus Professor Nick Europe-Finner et al.	Co-localisation of MMP-9 with neutrophils in stable lung transplant recipients - A potential role in Bronchiolitis Obliterans	2002
Professor Barbara Hanratty Professor Carl May Professor Christopher Ward	Doctors' perceptions of palliative care for heart failure: focus group study	2002
Professor Christopher Ward	European Community Respiratory Health Survey calibration project of dosimeter driving pressures	2002
Professor Christopher Ward	Increased soluble CD14 in bronchoalveolar lavage fluid of stable lung transplant recipients	2002
Professor Christopher Ward	Inhaled corticosteroid dosage in asthma - Reply	2002
Professor Christopher Ward Dr Douglas Reid	PD20 to methacholine is predicted by airway inflammation and remodelling: A systematic, longitudinal, steroid intervention study of airway biopsy (Ebb) and BAL parameters	2002
Professor Christopher Ward Professor Anthony De Soyza Andrew Fisher Dr Gary Pritchard Emeritus Professor Nick Europe-Finner et al.	Small airway reticular basement membrane (RBM) thickening in clinically stable lung transplant recipients (SLTR) is not affected by three months treatment with inhaled corticosteroids (ICS)	2002
Professor Christopher Ward Professor Anthony De Soyza Professor Andrew Fisher Emeritus Professor Nick Europe-Finner	The presence of quorum sensing signal molecules in clinically stable lung allograft recipients suggests bacterial biofilm biology	2002
Professor Christopher Ward	Bronchoalveolar lavage macrophage and lymphocyte phenotypes in lung transplant recipients	2001
Professor Christopher Ward	Effect of a Long-Acting β₂-Agonist over Three Months on Airway Wall Vascular Remodeling in Asthma	2001
Professor Christopher Ward	Eg-1 positive eosinophils in asthma - Reply	2001
Professor Christopher Ward	Iron overload and nitric oxide-derived oxidative stress following lung transplantation	2001
Professor Christopher Ward	Normally suppressing CD40 coregulatory signals delivered by airway macrophages to TH2 lymphocytes are defective in patients with atopic asthma	2001
Professor Christopher Ward	Reduced airway distensibility, fixed airflow limitation and airway wall remodelling in asthma	2001
Professor Christopher Ward	Reduced airway distensibility, fixed airflow limitation, and airway wall remodeling in asthma	2001
Professor Christopher Ward Nan Wang	Airway neutrophilia in stable and bronchiolitis obliterans syndrome patients following lung transplantation	2000
Professor Christopher Ward	Bronchoalveolar lavage cellular profiles in lung transplantation: the effect of inhaled corticosteroids	2000
Professor Christopher Ward	Bronchoalveolar lavage fluid urea as a measure of pulmonary permeability in healthy smokers	2000
Professor Christopher Ward	Post-lung transplant bronchiolitis obliterans syndrome (BOS) is characterized by increased exhaled nitric oxide levels and epithelial inducible nitric oxide synthase	2000
Professor Christopher Ward	Airway Vascular Changes in Lung Allograft Recipients	1999
Professor Christopher Ward	Modulatory effects of alveolar macrophages on CD4+ T-cell IL-5 responses correlate with IL-1beta, IL-6, and IL-12 production	1999