Publications by Dr Malcolm Brodlie - ePrints

Browsing publications by Dr Malcolm Brodlie.

Newcastle Authors	Title	Year
Dr Hannah Tumelty Dr Geoff Shenton Dr Malcolm Brodlie	Are trough tobramycin concentrations taken from a central venous catheter accurate enough to safely use?	2022
Dr Vrinda Nair Dr Prakash Kannan Loganathan Dr Mithilesh Lal Dr Helen Pringleton Dr Malcolm Brodlie et al.	Automatic oxygen control for reducing extremes of oxygen saturation: a randomised controlled trial	2022
Dr Michael Grayling Dr Ben Shillitoe Dr Malcolm Brodlie Dr Louise Michaelis	Characterising the allergic profile of children with cystic fibrosis	2022
Dr Joanne Martin Dr Jen Townshend Dr Malcolm Brodlie	Diagnosis and management of asthma in children	2022
Dr Carlos Echevarria Dr Simon Doe Dr Malcolm Brodlie Professor Christopher Ward Dr Stephen Bourke et al.	Elexacaftor-Tezacaftor-Ivacaftor improve Gastro-Oesophageal reflux and Sinonasal symptoms in advanced cystic fibrosis	2022
Dr Hafez Al-momani Dr Christopher Stewart Rhys Jones Amaran Krishnan Dr Andrew Robertson et al.	Exposure to bile and gastric juice can impact the aerodigestive microbiome in people with cystic fibrosis	2022
Dr Nicola Hall David Hamilton Professor John Simpson Steven Powell Dr Malcolm Brodlie et al.	Impact of COVID-19 on carers of children with tracheostomies	2022
Kim Keltie Dr Andrew Sims Dr Malcolm Brodlie Steven Powell	National Cohort Study of Health Care Resource Use after Pediatric Tracheostomy	2022
Dr Iram Haq Maryam Almulhem Simone Soars Dr Malcolm Brodlie	Precision Medicine Based on CFTR Genotype for People with Cystic Fibrosis	2022
Dr Malcolm Brodlie	The feasibility of home monitoring of young people with cystic fibrosis: Results from CLIMB-CF	2022
Dr Matthew Thomas Dr Noreen Zainal Abidin Dr Malcolm Brodlie	Treating nontuberculous mycobacteria in children with cystic fibrosis: a multicentre retrospective study	2022
JinHeng Lin Professor Michael Taggart Dr Lee Borthwick Professor Andrew Fisher Dr Malcolm Brodlie et al.	Acute cigarette smoke or extract exposure rapidly activates TRPA1-mediated calcium influx in primary human airway smooth muscle cells	2021
Dr Iram Haq Dr Mike Althaus Dr Vinciane Saint-Criq Dr Bernard Verdon Dr Jen Townshend et al.	Clinical and molecular characterisation of the R751L-CFTR mutation	2021
Dr Iram Haq Dr Malcolm Brodlie	Clinical characteristics of SARS-CoV-2 infection in children with cystic fibrosis: An international observational study	2021
Catherine Hatton Dr Rachel Botting Dr Maria Duenas Fadic Dr Iram Haq Dr Bernard Verdon et al.	Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2	2021
Aaron Gardner Dr Iram Haq Dr Malcolm Brodlie	Interferon regulatory factor 8 regulates expression of acid ceramidase and infection susceptibility in cystic fibrosis	2021
Dr Corey Chan Bruce Jaffray Dr Malcolm Brodlie Hany Gabra	Lung biopsy in children: when is it useful?	2021
Dr Malcolm Brodlie	Successful biodegradable stent insertion in an infant with severe bronchomalacia and cystic fibrosis	2021
Jason Powell Dr Rachel Agbeko Dr Malcolm Brodlie Steven Powell	Tracheostomy trends in paediatric intensive care	2021
Dr Noreen Zainal Abidin Aaron Gardner Dr Iram Haq Dr Matthew Thomas Dr Malcolm Brodlie et al.	Trends in nontuberculous mycobacteria infection in children and young people with cystic fibrosis	2021
Dr Malcolm Brodlie	Developing a core outcome set for children with protracted bacterial bronchitis	2020
Dr Joy Allen Dr Andrea Gonzalez-Ciscar Dr Clare Lendrem Dr Jana Suklan Dr Louise Johnston et al.	Diagnostic and economic evaluation of a point-of-care test for respiratory syncytial virus	2020
Dr Malcolm Brodlie	Neutrophils in community-acquired pneumonia: parallels in dysfunction at the extremes of age	2020
Dr Jessica Roberts Jason Powell Dr Jake Begbie Dr Gerard Siou Andrew Welch et al.	Pediatric tracheostomy: A large single-center experience	2020
Dr Aaron Ions Gardner Dr Iram Haq Professor John Simpson Dr Vinciane Saint-Criq Dr Bernard Verdon et al.	Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis	2020
Dr Ugo Offor Dr Christopher Bacon Dr Jessica Roberts Jason Powell Dr Malcolm Brodlie et al.	Transplantation For Congenital Heart Disease Is Associated With An Increased Risk Of Epstein-Barr Virus-Related Post-Transplant Lymphoproliferative Disorder In Children	2020
Dr Aaron Ions Gardner Dr Malcolm Brodlie Dr Matthew Thomas	Epidemiology of Nontuberculous Mycobacteria Infection in Children and Young People with Cystic Fibrosis: Analysis of UK Cystic Fibrosis Registry	2019
Dr Iram Haq Dr Noreen Zainal Abidin Attaybenes Socas Rodríguez Dr Andrea Gonzalez-Ciscar Dr Aaron Ions Gardner et al.	Modulator therapies for cystic fibrosis	2019
Dr Zheyi Liew Dr Alan Fenton Dr Sundeep Harigopal Dr Saikiran Gopalakaje Dr Malcolm Brodlie et al.	Physiological effects of high-flow nasal cannula therapy in preterm infants	2019
Dr Vinciane Saint-Criq Dr Iram Haq Dr Aaron Ions Gardner Professor Christopher Ward Dr Malcolm Brodlie et al.	Real-Time, Semi-Automated Fluorescent Measurement of the Airway Surface Liquid pH of Primary Human Airway Epithelial Cells	2019
Patrizia Calella Dr Malcolm Brodlie Professor Lorenzo Donini Dr Mario Siervo	Tools and Methods Used for the Assessment of Body Composition in Patients With Cystic Fibrosis: A Systematic Review	2019
Dr Jessica Roberts Jason Powell Dr Michael Mather Steven Powell Dr Malcolm Brodlie et al.	A review of adenotonsillar hypertrophy and adenotonsillectomy in children after solid organ transplantation	2018
Patrizia Calella Dr Matthew Thomas Dr Malcolm Brodlie Dr Mario Siervo	Association between body composition and pulmonary function in children and young people with cystic fibrosis	2018
Patrizia Calella Dr Malcolm Brodlie Professor Lorenzo Donini Dr Mario Siervo	Cystic fibrosis, body composition, and health outcomes: a systematic review	2018
Dr Tom Altmann Dr James Slack Dr Mary Slatter Professor Andrew Cant Dr Matthew Thomas et al.	Endothelial cell damage in idiopathic pneumonia syndrome	2018
Dr Adrien Tissot Dr Matthew Thomas Emeritus Professor Nick Europe-Finner Dr Malcolm Brodlie	NonTuberculous Mycobacteria infection and lung transplantation in cystic fibrosis: A worldwide survey of clinical practice	2018
Rhys Jones Amaran Krishnan Dr Malcolm Brodlie Professor Jeffrey Pearson Professor Stephen Bourke et al.	Risk factors for lung disease progression in children with cystic fibrosis	2018
Dr Aaron Ions Gardner Dr Malcolm Brodlie	Role of Sphingolipids in Bacterial Infections	2018
Dr Aaron Ions Gardner Dr Malcolm Brodlie	Sphingolipids as targets for inhalation treatment of cystic fibrosis	2018
Dr Noreen Zainal Abidin Dr Iram Haq Dr Aaron Ions Gardner Dr Malcolm Brodlie	Ataluren in cystic fibrosis: development, clinical studies and where are we now?	2017
Dr Malcolm Brodlie	Characterisation of eppin function: expression and activity in the lung	2017
Salam Ibrahim Mark Turner Dr Vinciane Saint-Criq Dr James Garnett Dr Iram Haq et al.	CK2 is a key regulator of SLC₄A2- mediated Cl-/HCO₃- exchange in human airway epithelia	2017
Dr Matthew Thomas Nicholas Robertson Dr Nicola Miller Professor Judith Rankin Dr Michael McKean et al.	Congenital lung agenesis: incidence and outcome in the North of England	2017
Dr Malcolm Brodlie	How to use nasal nitric oxide in a child with suspected primary ciliary dyskinesia	2017
Dr Hafez Al-momani Rhys Jones Professor Stephen Bourke Dr Simon Doe Dr John Perry et al.	Nontuberculous mycobacteria in gastrostomy fed patients with cystic fibrosis	2017
Dr Iram Haq Dr Michael McKean Dr Malcolm Brodlie	Should we use montelukast in wheezy children?	2017
Dr Zheyi Liew Professor Kate Gould Dr Su Bunn Dr Matthew Thomas Dr James Lordan et al.	Successful outcome following pneumonectomy in a teenage boy with cystic fibrosis: a case report.	2017
Dr Aaron Ions Gardner Professor Christopher Ward Dr Malcolm Brodlie	β1-integrin accumulates in cystic fibrosis luminal airway epithelial membranes and decreases sphingosine promoting bacterial infections	2017
Dr Iram Haq Dr Aaron Ions Gardner Dr Malcolm Brodlie	A multifunctional bispecific antibody against Pseudomonas aeruginosa as a potential therapeutic strategy	2016
Dr Alison Robb Dr Matthew Thomas Dr Malcolm Brodlie Dr Stephen Bourke Dr John Perry et al.	A novel culture medium for isolation of rapidly-growing mycobacteria from the sputum of patients with cystic fibrosis	2016
Dr Iram Haq Dr Michael Gray Dr James Garnett Professor Christopher Ward Dr Malcolm Brodlie et al.	Airway surface liquid homeostasis in cystic fibrosis: pathophysiology and therapeutic targets	2016
Dr James Garnett Dr Georgina Carr Jason Powell Dr Malcolm Brodlie Professor Christopher Ward et al.	Hyperglycaemia and Pseudomonas aeruginosa acidify cystic fibrosis airway surface liquid by elevating epithelial monocarboxylate transporter 2 dependent lactate-H⁺ secretion	2016
Professor Christopher Ward Emeritus Professor Nick Europe-Finner Dr Malcolm Brodlie	IL-22 exacerbates weight loss in a murine model of chronic pulmonary Pseudomonas aeruginosa infection	2016
Nicholas Robertson Professor Judith Rankin Dr Michael McKean Dr Malcolm Brodlie Dr Matthew Thomas et al.	Incidence and outcome of congenital lung agenesis in the north of England	2016
Gemma Zeybel Professor Jeffrey Pearson Amaran Krishnan Dr Stephen Bourke Dr Simon Doe et al.	Ivacaftor and symptoms of extra-oesophageal reflux in patients with cystic fibrosis and G551D mutation	2016
Dr Malcolm Brodlie Dr Michael McKean	Leukotriene receptor antagonists as maintenance or intermittent treatment in pre-school children with episodic viral wheeze	2016
Dr Hafez Al-momani Dr Christopher Stewart Rhys Jones Amaran Krishnan Dr Andrew Robertson et al.	Microbiological profiles of sputum and gastric juice aspirates in Cystic Fibrosis patients	2016
Emily Ward-Booth Dr David Spencer Professor Stephen Rushton Dr Malcolm Brodlie Dr Matthew Thomas et al.	Predictors of primary treatment failure in children with empyema	2016
Dr Alice Wort Professor John Simpson Dr David Spencer Dr Matthew Thomas Dr Malcolm Brodlie et al.	Viruses associated with community-acquired pneumonia in children – a large prospective study in the post-prevenar 13 era	2016
Dr James Garnett Dr Michael Gray Dr Malcolm Brodlie Professor Christopher Ward	Airway epithelial cells secrete bicarbonate in response to acidic by-products of pseudomonas aeruginosa metabolism	2015
Dr Malcolm Brodlie Ali Aseeri Dr James Lordan Dr Andrew Robertson Dr Michael McKean et al.	Bile acid aspiration in people with cystic fibrosis before and after lung transplantation	2015
Dr Alison Robb Dr Malcolm Brodlie Dr Stephen Bourke Dr John Perry	Comparison of various culture media for the isolation of non-tuberculous mycobacteria from respiratory samples from patients with cystic fibrosis	2015
Dr Malcolm Brodlie Dr Michael McKean	Leukotriene receptor antagonists as maintenance and intermittent therapy for episodic viral wheeze in children	2015
Dr Malcolm Brodlie Dr Iram Haq Keith Roberts	Targeted therapies to improve CFTR function in cystic fibrosis	2015
Dr Iram Haq Dr Saikiran Gopalakaje Dr Alan Fenton Dr Michael McKean Dr Malcolm Brodlie et al.	The evidence for high flow nasal cannula devices in infants	2014
Dr Shruti Parikh Dr Andrew Robertson Dr Malcolm Brodlie Emeritus Professor Nick Europe-Finner Professor Christopher Ward et al.	Are the enzymatic methods currently being used to measure bronchoalveolar lavage bile salt levels fit for purpose?	2013
Professor Michael Griffin Dr Andrew Robertson Dr Iain Brownlee Rachel Stovold Dr Malcolm Brodlie et al.	Aspiration and Allograft Injury Secondary to Gastroesophageal Reflux Occur in the Immediate Post-Lung Transplantation Period (Prospective Clinical Trial)	2013
Dr James Garnett Dr Michael Gray Dr Malcolm Brodlie Professor Christopher Ward Erin Baker et al.	Elevated Paracellular Glucose Flux across Cystic Fibrosis Airway Epithelial Monolayers Is an Important Factor for Pseudomonas aeruginosa Growth	2013
Amaran Krishnan Dr Malcolm Brodlie Emeritus Professor Nick Europe-Finner Professor Michael Griffin Dr Ian Forrest et al.	Identical Biofilm Forming Strains of Pseudomonas aeruginosa Occur in Lung Allograft BAL and Gastric Juice from CF Patients with Gastro Oesophageal Reflux	2013
Dr Malcolm Brodlie Professor Christopher Ward Emeritus Professor Nick Europe-Finner	Novel T helper cell responses against Pseudomonas aeruginosa in healthy individuals and patients with cystic fibrosis	2013
Dr Michael McKean Dr Malcolm Brodlie	Oesophageal foreign body presenting with stridor associated with feeding	2013
Dr Saikiran Gopalakaje Dr Alan Fenton Dr Michael McKean Dr Malcolm Brodlie	The evidence for high flow nasal cannula devices in infants	2013
Dr Lee Borthwick Emeritus Professor Nick Europe-Finner Dr Rahul Mahida Andrew Walker Aaron Gardner et al.	TNFα From Classically Activated Macrophages Accentuates Epithelial to Mesenchymal Transition in Obliterative Bronchiolitis	2013
Ali Aseeri Dr Malcolm Brodlie Dr James Lordan Emeritus Professor Nick Europe-Finner Professor Jeffrey Pearson et al.	Bile Acids Are Present in the Lower Airways of People with Cystic Fibrosis	2012
Dr Malcolm Brodlie Claire Graham Dr Michael McKean	Childhood cough	2012
Dr Malcolm Brodlie Emeritus Professor Nick Europe-Finner Dr James Lordan Professor Christopher Ward	Interleukin-17 and Cystic Fibrosis Lung Disease	2012
Dr Matt Bates Dr Victoria Nesbitt Dr Langping He Dr Charlotte Alston Dr Malcolm Brodlie et al.	Mitochondrial respiratory chain disease in children undergoing cardiac transplantation: A prospective study	2012
Dr Malcolm Brodlie Dr David Spencer	Omalizumab for the Treatment of Paediatric Asthma	2012
Dr Aaron Ions Gardner Professor Andrew Fisher Christine Richter Grace Johnson Dr Elizabeth Moisey et al.	The Critical Role of TAK1 in Accentuated Epithelial to Mesenchymal Transition in Obliterative Bronchiolitis after Lung Transplantation	2012
Dr Malcolm Brodlie Dr Terence Flood Dr David Spencer	The importance of thorough investigation of children with wet cough	2012
Dr Malcolm Brodlie Dr Michael McKean Dr Samantha Moss Dr David Spencer	The oral corticosteroid-sparing effect of omalizumab in children with severe asthma	2012
Dr Malcolm Brodlie Dr David Spencer	Use of somatostatin analogues to treat chylothorax in a child with Generalised Lymphatic Dysplasia	2012
Dr Malcolm Brodlie Dr Matthew Thomas Dr David Spencer	Vitamin D in children with cystic fibrosis	2012
Dr Lee Borthwick Dr John Perry Dr Malcolm Brodlie Professor Christopher Ward Katherine Gould et al.	Pseudomonas aeruginosa accentuates epithelial-to-mesenchymal transition in the airway	2011
Dr Malcolm Brodlie Dr James Lordan Professor Christopher Ward	Can cells other than Th17 lymphocytes be important sources of IL-17 in the lungs?	2011
Dr Malcolm Brodlie Dr James Lordan Professor Christopher Ward	Ceramide and cystic fibrosis lung disease	2011
Dr Malcolm Brodlie Dr Michael McKean Andrew Welch	Inflammatory myofibroblastic tumours of the respiratory tract: paediatric case series with varying clinical presentations	2011
Dr Lee Borthwick Phil Botha Dr Malcolm Brodlie Aaron Gardner Dr David Bourn et al.	Is CFTR-delF508 Really Absent from the Apical Membrane of the Airway Epithelium?	2011
Dr Malcolm Brodlie Dr Michael McKean Dr Amy Anderson Professor Catharien Hilkens Professor Andrew Fisher et al.	Raised interleukin-17 is immunolocalised to neutrophils in cystic fibrosis lung disease	2011
Dr Malcolm Brodlie Dr Michael McKean Dr Joseph Gray Professor Andrew Fisher Emeritus Professor Nick Europe-Finner et al.	Ceramide is Increased in the Lower Airway Epithelium of People with Advanced Cystic Fibrosis Lung Disease	2010
Dr Malcolm Brodlie	Exhaled nitric oxide in the diagnosis of childhood asthma	2010
Dr Lee Borthwick Marta Gorowiec Dr Malcolm Brodlie Professor Christopher Ward Dr James Lordan et al.	Inflammation and Epithelial to Mesenchymal Transition in Lung Transplant Recipients: Role in Dysregulated Epithelial Wound Repair	2010
Dr Malcolm Brodlie Dr Michael McKean Dr John Perry Dr Burns Verdon Dr Michael Gray et al.	Primary bronchial epithelial cell culture from explanted cystic fibrosis lungs	2010
Dr Lee Borthwick Dr Malcolm Brodlie Professor Christopher Ward Dr John Perry Emeritus Professor Nick Europe-Finner et al.	The M1 macrophage phenotype accentuates TGF-beta 1 driven epithelial to mesenchymal transition (EMT) via the secretion of TNF alpha	2010
Dr Aaron Ions Gardner Dr Malcolm Brodlie Professor Derek Mann Dr Lee Borthwick Professor Andrew Fisher et al.	The role of transforming growth factor-beta activated kinase-1 (TAK-1) in the development of airway fibrosis	2010
Dr Malcolm Brodlie Professor Catharien Hilkens Professor Christopher Ward	Airway epithelial cells as guardians of immune homeostasis?	2009
Professor Christopher Ward Julie Diboll Professor Andrew Fisher Dr Malcolm Brodlie Dr James Lordan et al.	Bronchial epithelial cells cultured from clinically stable lung allograft patients promote the development of macrophages from monocytes rather than dendritic cells	2009
Dr Malcolm Brodlie Dr David Spencer	Bronchomalacia occurring in monozygotic twins - Further information about its inheritance	2009
Dr Malcolm Brodlie Dr David Spencer	Bronchomalacia occurring in monozygotic twins - further information about its inheritance	2009
Dr Malcolm Brodlie Dr Michael McKean Professor Andrew Fisher Emeritus Professor Nick Europe-Finner Dr James Lordan et al.	Ceramide is increased and associated with neutrophilic inflammation in the lower airway epithelium of people with cystic fibrosis	2009
Dr Malcolm Brodlie Dr Michael McKean	Exhaled nitric oxide in the diagnosis of childhood asthma	2009
Dr Malcolm Brodlie Dr Terence Flood Dr David Spencer	Heterogeneity in the clinical manifestations of mannose-binding lectin deficiency	2009
Dr Malcolm Brodlie Dr Terence Flood Dr Fiona Black Dr David Spencer	Lymphoid bronchiolitis presenting at birth in an immunocompetent child: Chronic interstitial lung disease of unknown aetiology	2009
Dr Malcolm Brodlie Dr Michael McKean	Picture quiz: Dyspnoea and cough in a toddler	2009
Dr Lee Borthwick Dr Malcolm Brodlie Professor Christopher Ward Dr James Lordan Professor John Kirby et al.	Pro-inflammatory Cytokines IL-1 beta and TNT alpha, but Not IL-8, Cause Aberrant Lung Epithelial Wound Repair Via TGF-beta 1 Driven Epithelial to Mesenchymal Transition (EMT)	2009
Dr Malcolm Brodlie Dr Michael McKean Professor Andrew Fisher Emeritus Professor Nick Europe-Finner Dr James Lordan et al.	Reticular basement membrane thickening in end-stage cystic fibrosis lung disease	2009
Dr Malcolm Brodlie Dr David Spencer	Growth recovery after withdrawal of inappropriate inhaled fluticasone proprionate	2008
Dr Malcolm Brodlie Dr Michelle Muller Dr Leslie Mitchell Dr David Spencer	High-resolution computed tomography in children with confirmed post-infectious obliterative bronchiolitis	2008
Dr Malcolm Brodlie	Hypertrophic cardiomyopathy and transposition of great arteries associated with maternal diabetes and presumed gestational diabetes	2008
Dr Malcolm Brodlie	Prostaglandin therapy for ductal patency: how long is too long?	2008
Dr Malcolm Brodlie Dr Michael McKean	Strategies to screen for adrenal suppression in children with asthma: there is no consensus among UK centres	2008
Dr Malcolm Brodlie Dr Michael McKean Dr John Perry Anne Nicholson Professor Jeffrey Pearson et al.	The culture of primary bronchial epithelial cells from the lungs of people with cystic fibrosis removed at the time of transplantation: a model to study cystic fibrosis lung disease	2008
Dr Malcolm Brodlie	Compliance with inhaled corticosteroids is important when considering adrenal suppression	2007
Dr Malcolm Brodlie Dr Jonathan Wyllie	Interference of electrocardiographic recordings by a mobile telephone	2007
Dr Malcolm Brodlie	Strategies to screen for adrenal suppression in children with asthma should take account of compliance with inhaled corticosteroids	2007
Dr Christian Harkensee Dr Malcolm Brodlie Professor Nicholas Embleton Dr Michael McKean	Passive immunisation of preterm infants with palivizumab against RSV infection	2006
Dr Malcolm Brodlie	Ten years of neonatal autopsies in tertiary referral centre: retrospective study	2002
Dr Malcolm Brodlie	Characterization of Strains of Mycoplasma mycoides subsp. mycoides Small Colony Type Isolated from Recent Outbreaks of Contagious Bovine Pleuropneumonia in Botswana and Tanzania: Evidence for a New Biotype.	2000
Dr Malcolm Brodlie	Comparison of the virulence of European and African isolates of Mycoplasma mycoides subspecies mycoides small colony type	2000