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Complement fixing antibody responses to virus infection in children with acute lymphoblastic leukaemia

Lookup NU author(s): Emeritus Professor Alan Craft, Dr Michael Reid


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Thirty children with acute lymphoblastic leukaemia (ALL) were studied and had a virus isolated. Only 50% produced a significant rise in complement fixing (CF) antibody titre compared to 100% of normal children. The failure to produce antibodies was unpredictable. CF antibodies are not a reliable guide to virus infections in children with ALL.

Publication metadata

Author(s): Craft, A. W., Reid, M. M., McQuillin, J., Gardner, P. S.

Publication type: Article

Publication status: Published

Journal: Journal of Clinical Pathology

Year: 1980

Volume: 33

Issue: 8

Pages: 735-737

Print publication date: 01/08/1980

ISSN (print): 0021-9746

ISSN (electronic): 1472-4146


DOI: 10.1136/jcp.33.8.735

PubMed id: 6933155


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