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Cytogenetic analysis of a congenital fibrosarcoma

Lookup NU author(s): Professor Archibald Malcolm, Professor Andrew Pearson, Emeritus Professor Alan Craft


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Congenital (infantile) fibrosarcoma is a rare soft tissue sarcoma occurring in children aged less than 5 years. We performed cytogenetic analysis on such a tumor, which had an abnormal karyotype: 48,XY, + 11, + 20. Three other reports of karyotypes in congenital fibrosarcoma describe similar cytogenetic changes, and a specific pattern of trisomies that may prove diagnostic for this tumor is beginning to emerge.

Publication metadata

Author(s): Adam, L. R., Davison, E. V., Malcolm, A. J., Pearson, A. D. J., Craft, A. W.

Publication type: Article

Publication status: Published

Journal: Cancer Genetics and Cytogenetics

Year: 1991

Volume: 52

Issue: 1

Pages: 37-41

Print publication date: 01/03/1991

ISSN (print): 0165-4608

ISSN (electronic): 1873-4456


DOI: 10.1016/0165-4608(91)90051-U

PubMed id: 2009510


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