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Serological study of Pneumocystis carinii infection in the absence of immunosuppression

Lookup NU author(s): Emeritus Professor Alan Craft

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Abstract

Serum samples from 145 children with no known immunosuppressive illness were examined by indirect immunofluorescence for antibody to Pneumocystis carinii. Positive antibody titres (greater than or equal to 1:8 dilution) were found in 69 children (48%). Antibody could not be detected in the remaining children. Previous studies have shown that at least 75% of children have antibodies to P. carinii by the age of 4 years. This study shows a lower percentage of children with detectable antibody. This may be related to geographical variation of antigen or possibly to the widespread use of co-trimoxazole.

Publication metadata

Author(s): Gerrard, M. P., Eden, O. B., Jameson, B., Craft, A. W.

Publication type: Article

Publication status: Published

Journal: Archives of Disease in Childhood

Year: 1987

Volume: 62

Issue: 2

Pages: 177-179

Print publication date: 01/02/1987

ISSN (print): 0003-9888

ISSN (electronic): 1468-2044

URL: http://dx.doi.org/10.1136/adc.62.2.177

DOI: 10.1136/adc.62.2.177

PubMed id: 3493735

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