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Cytogenetic abnormalities in a primitive neuroectodermal tumor

Lookup NU author(s): Dr Nicholas Bown, Professor Andrew Pearson, Professor Archibald Malcolm

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Abstract

Two distinct karyotypically abnormal cell lines were observed in cultures of a primitive neuroectodermal tumor. One involved multiple chromosome rearrangements, and the other an inversion of chromosome #7 and a t(3;10) showing an interstitial deletion of 3p; del(3)(p1?4p1?2). None of these rearrangements have been reported in previous descriptions of primitive neuroectodermal tumor karyotypes.

Publication metadata

Author(s): Bown NP, Davison EV, Pearson ADJ, Malcolm AJ

Publication type: Article

Publication status: Published

Journal: Cancer Genetics and Cytogenetics

Year: 1988

Volume: 32

Issue: 2

Pages: 247-252

ISSN (print): 0165-4608

ISSN (electronic): 1873-4456

URL: http://dx.doi.org/10.1016/0165-4608(88)90287-7

DOI: 10.1016/0165-4608(88)90287-7

PubMed id: 2835148

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