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Secondary chronic myelomonocytic leukemia with t(9;11) in a child

Lookup NU author(s): Professor Andrew Pearson, Jerome Evans, Dr Michael Reid


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Chronic myelomonocytic leukemia (CMMol) developed in a 10-year-old girl after treatment of non-Hodgkin's lymphoma with a regimen which did not contain epipodophyllotoxins. t(9;11)(p22;q23) was found in the leukemic cells. This case highlights the fact that secondary hemopoietic malignancies with 11q23 abnormalities are not restricted to patients treated with epipodophyllotoxins, expands the number of documented cases of secondary myelodysplasia in children, and adds CMMoL to the spectrum of hemopoietic malignancies associated with t(9;11).

Publication metadata

Author(s): George R, Pearson ADJ, Evans J, Reid MM

Publication type: Note

Publication status: Published

Journal: Cancer Genetics and Cytogenetics

Year: 1994

Volume: 75

Issue: 1

Pages: 64-66

ISSN (print): 0165-4608

ISSN (electronic): 1873-4456


DOI: 10.1016/0165-4608(94)90217-8

PubMed id: 8039167