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Lookup NU author(s): Professor David BurnORCiD, Dr Uma Nath, Sarah Daniel
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Alpha synuclein, tau, synphilin, and APOE genotypes were analyzed in patients with multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) and controls. The predisposing effect of the tau insertion polymorphism to the development of PSP is confirmed. However, no effect of alpha -synuclein, synphilin, or APOE variability on the development of PSP, or of tan, alpha -synuclein, APOE, or synphilin gene variability on the development of MSA, are demonstrated.
Author(s): Morris HR, Vaughan JR, Datta SR, Bandopadhyay R, de Silva HAR, Schrag A, Cairns NJ, Burn D, Nath U, Lantos PL, Daniel S, Lees AJ, Quinn NP, Wood NW
Publication type: Letter
Publication status: Published
Journal: Neurology
Year: 2000
Volume: 55
Issue: 12
Pages: 1918-1920
ISSN (print): 0028-3878
ISSN (electronic): 1526-632X
URL: http://www.neurology.org/content/55/12/1918