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Verrucous carcinoma of the paranasal sinuses: Case report and clinical update

Lookup NU author(s): Professor Vinidh Paleri

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Abstract

Background. Verrucous carcinoma is a low-grade malignancy that has been reported to occur in all anatomic sites of the head and neck. Fourteen cases of verrucous carcinoma of paranasal sinus origin have been reported to date in the English literature. Methods. Case report and retrospective review of all cases of verrucous carcinoma of the paranasal sinuses in the English literature. All authors were contacted to provide missing data and long-term follow-up. Results. Five of the eight authors contacted responded, and the most current data from all 15 cases were compiled. Eleven of the 15 patients (73%) were men and ranged in age from 35 to 81 years (median, 68 years). The maxillary sinus was the most common paranasal sinus involved (93%). Presentation often occurred late, with 12 of 15 (80%) initially being seen at stage T3 or higher. Surgical excision was the treatment of choice, and median disease-free survival was 54 months. Conclusions. Verrucous carcinoma of the paranasal sinuses is a rare but potentially curable disease. Treatment is surgical, and prognosis is good with early intervention. (C) 2004 Wiley Periodicals, Inc.

Publication metadata

Author(s): Paleri V, Orvidas LJ, Wight RG, Bradley PJ

Publication type: Article

Publication status: Published

Journal: Head & Neck: journal for the sciences and specialities of the head and neck

Year: 2004

Volume: 26

Issue: 2

Pages: 184-189

ISSN (print): 1043-3074

ISSN (electronic): 1097-0347

Publisher: John Wiley & Sons, Inc

URL: http://dx.doi.org/10.1002/hed.10230

DOI: 10.1002/hed.10230

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