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Lookup NU author(s): Dr Niamh Leonard,
Dr Edmund Ong,
Dr Clifford Lawrence
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Since 1991 infrequent reports have described a distinctive triad of nodulocystic acne, striking follicular spines and an eruption resembling pityriasis rubra pilaris (PRP) in HIV-positive patients. It has been suggested that this may represent a subtype of PRP, or alternatively that it should be viewed as a unique HIV-associated follicular occlusion triad. Clinical manifestations may be severe, and in several cases have been ultimately fatal, with death occurring due to complications of cutaneous sepsis. We describe a case demonstrating severe conglobate acne, follicular keratotic spines and histologically confirmed PRP in association with HIV infection. Clinical features and treatment modalities of previously reported cases are reviewed. Despite refusing all topical and systemic treatment our patient showed spontaneous remission of skin signs after 2 years.
Author(s): Blasdale C, Turner RJ, Leonard N, Ong ELC, Lawrence CM
Publication type: Article
Publication status: Published
Journal: Clinical and Experimental Dermatology
ISSN (print): 0307-6938
ISSN (electronic): 1365-2230
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