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Lookup NU author(s): Wolfgang Issing
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Background: Patients with gastroesophageal reflux disease may suffer from a variety of symptoms from the upper aerodigestive tract. The objective of this study was to determine the impact of dual-probe 24-hr pH monitoring in the diagnosis of reflux-related otolaryngological disorders. Methods: Twenty-two patients with symptoms such as chronic cough, globus pharyngeus, heartburn, dysphonia and burning sensation of the tongue underwent a complete ear, nose and throat examination, 24-hr dual-probe pH monitoring, and oesophago-gastro-duodenoscopy. Results: pH monitoring revealed gastroesophageal (distal) reflux in all patients and pharyngeal (proximal) reflux in 21 patients. Treatment consisted of a proton pump inhibitor (esomeprazole). Within 4 weeks 68 per cent of patients had no laryngopharyngeal symptoms; within 8 weeks 95 per cent of patients were symptom-free. Conclusions: Patients with atypical reflux symptoms such as hoarseness, globus sensation or throat-clearing responded well to anti-reflux treatment.
Author(s): Issing WJ, Karkos RD, Perreas K, Folwaczny C, Reichelt O
Publication type: Article
Publication status: Published
Journal: Journal of Laryngology and Otology
Year: 2004
Volume: 118
Issue: 11
Pages: 845-848
ISSN (print): 0022-2151
ISSN (electronic): 1748-5460
Publisher: Cambridge University Press
URL: http://dx.doi.org/10.1258/0022215042703660
DOI: 10.1258/0022215042703660
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