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Lookup NU author(s): Dr Kevin Windebank,
Dr Michael Lowry,
Professor Andrew Pearson
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Two cases of non-familial haemophagocytic lymphohistiocytosis (HLH) are presented in which treatment with interferon alfa and gammaglobulin was associated with complete clinical remission. In one case, serological evidence of recent Epstein-Barr virus infection was found. Natural killer cell activity was within normal limits in both children, compatible with a secondary form of HLH. The combination of interferon alfa and intravenous gammaglobulin requires further evaluation in the treatment of nonfamilial HLH.
Author(s): Estlin EJ, Palmer RD, Windebank KP, Lowry MF, Pearson ADJ
Publication type: Article
Publication status: Unknown
Journal: Archives of Childhood Diseases
Print publication date: 01/11/1996
ISSN (print): 0003-9888
ISSN (electronic): 1468-2044
Publisher: BMJ Publishing
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