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The synthesis and evaluation of some coumarin derivatives as fluorescent indicators of nitroreductase activity

Lookup NU author(s): Dr John Perry

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Abstract

The carbamate 8 was reacted with appropriate P-keto esters in a Pechmann reaction giving the coumarin derivatives 9-11 bearing 4-nitrobenzylcarbamoyl triggers. These compounds were assessed as potential indicators of nitroreductase activity.

Publication metadata

Author(s): James AL, Perry JD, Stanforth SP

Publication type: Article

Publication status: Published

Journal: Journal of Heterocyclic Chemistry

Year: 2006

Volume: 43

Issue: 2

Pages: 515-517

ISSN (print): 0022-152X

ISSN (electronic): 1943-5193

Publisher: Wiley-Blackwell

URL: http://dx.doi.org/10.1002/jhet.5570430241

DOI: 10.1002/jhet.5570430241

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