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The evidence for cerebral protection: An analysis and summary of the literature

Lookup NU author(s): Dr Sumaira MacDonald


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It has been considered likely that the majority of cerebral ischaemic episodes following carotid artery stenting are due to cerebral embolisation. It is intuitive therefore, to attempt to prevent these presumptive emboli, whether they are comprised of air or formed elements, from reaching the brain. Various pharmacological and mechanical solutions are being used. The available literature is hampered by comparisons against historical controls of unprotected CAS with many confounding variables that may influence outcome. There is no clinical Level-I evidence to support the use of protection devices but Level-III and Level-IV evidence suggest benefit. (C) 2006 Published by Elsevier Ireland Ltd.

Publication metadata

Author(s): Macdonald S

Publication type: Article

Publication status: Published

Journal: European Journal of Radiology

Year: 2006

Volume: 60

Issue: 1

Pages: 20-25

ISSN (print): 0720-048X

ISSN (electronic): 1872-7727

Publisher: Elsevier


DOI: 10.1016/j.ejrad.2006.05.027


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