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Immunocytochemical detection of tumours of neuroectodermal origin

Lookup NU author(s): Dr Peter Carey, Professor Archibald Malcolm, Professor Andrew Pearson, Dr Michael Reid


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Immunocytochemical methods were applied to bone marrow aspirate and cerebrospinal fluid specimens to show cellular reactivity with the monoclonal antibody UJ13A, which recognises an antigen expressed by cells of neuroectodermal origin. The antigen remained stable after air drying and appropriate fixation. In five patients with various neuroectodermal tumours the diagnostic advantages of these techniques were clear; they can be performed even when only very small amounts of diagnostic material are available.

Publication metadata

Author(s): Carey PJ, Malcolm AJ, Pearson ADJ, Kemshead JT, Reid MM

Publication type: Article

Publication status: Published

Journal: Journal of Clinical Pathology

Year: 1988

Volume: 41

Issue: 5

Pages: 586-589

Print publication date: 01/05/1988

ISSN (print): 0021-9746

ISSN (electronic): 1472-4146


DOI: 10.1136/jcp.41.5.586

PubMed id: 3290267


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