ePrints

Phase I trials in paediatric oncology - The European perspective - On behalf of the new agents group of the United Kingdom Childrens Cancer Study Group

Lookup NU author(s): Professor Herbie Newell, Professor Andrew Pearson

Downloads

Full text for this publication is not currently held within this repository. Alternative links are provided below where available.

Abstract

The current recommendations for Phase I trials should allow more confident interpretation of the toxicity and efficacy of new agents by providing a framework for multicentre and international co-operation. An overview of the aims and designs of Phase I trials is presented, along with a summary of current and recently published United Kingdom Childrens Cancer Study Group Phase I trials, and a discussion of some of the difficulties faced in the methodology and evaluation of Phase I studies in children.

Publication metadata

Author(s): Estlin EJ, Ablett S, Newell DR, Lewis IJ, Lashford L, Pearson ADJ

Publication type: Article

Publication status: Published

Journal: Investigational New Drugs

Year: 1996

Volume: 14

Issue: 1

Pages: 23-32

ISSN (print): 0167-6997

ISSN (electronic): 1573-0646

URL: http://dx.doi.org/10.1007/BF00173679

DOI: 10.1007/BF00173679

PubMed id: 8880390

Altmetrics

Share