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Lookup NU author(s): Dr Anita Nolan,
Emeritus Professor Robin Seymour
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The aim of this study was to evaluate the efficacy of a topical hyaluronic acid (HA) gel preparation (0.2%) in the management of oral lichen planus (OLP). A total of 124 patients with erosive OLP participated in a randomized, placebo-controlled, double-blind trial to evaluate the efficacy of a topical HA preparation. Outcome measures included soreness relief following immediate application, oral function and size of erosive/ulcerative area. Patients were medicated for 28 days and completed a log diary recording oral function and soreness scores. Application of topical HA produced a significant reduction (P 0.05) with respect to oral function. Patients treated with 0.2% HA showed a significant reduction (P
Author(s): Nolan A, Badminton J, Maguire J, Seymour RA
Publication type: Article
Publication status: Published
Journal: Journal of Oral Pathology & Medicine
ISSN (print): 0904-2512
ISSN (electronic): 1600-0714
Publisher: Wiley-Blackwell Publishing Ltd.
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