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Lookup NU author(s): Dr Debbie Riby
Interventions aimed at improving glucose regulatory mechanisms have been suggested as a possible source of cognitive enhancement in the elderly. In particular, previous research has identified episodic memory as a target For facilitation after either moderate increases in glycaemia (after a glucose drink) or after improvements in glucose regulation. The present study aimed to extend this research by examining the joint effects of glucose ingestion and glucose regulation oil cognition. In addition, risk factors associated with the development of poor glucose regulation in middle-aged adults were considered. In a repeated measures design. thirty-three middle-aged adults (aged 35-55 years) performed a battery of memory and non-memory tasks after either 25 g or 50 g glucose or a sweetness matched placebo drink. To assess the impact of individual differences in glucose regulation. blood glucose measurements were taken oil four occasions during testing. A lifestyle and diet questionnaire was also administered. Consistent with previous research. episodic memory ability benefited front glucose ingestion when task demands were high. Blood glucose concentration was also found to predict performance across a number of cognitive domains. Interestingly. the risk factors associated with poor glucose regulation Were linked to dietary impacts traditionally associated with poor health. e.g. the consumption of high-sugar sweets and drinks. The research replicates earlier work suggesting that task demands are critical to the glucose facilitation effect. Importantly, the data demonstrate clear associations between elevated glycaemia and relatively poor cognitive performance, which may be partly due to the effect of dietary and lifestyle factors.
Author(s): Riby LM, McLaughlin J, Riby DM, Graham C
Publication type: Article
Publication status: Published
Journal: British Journal of Nutrition
Year: 2008
Volume: 100
Issue: 5
Pages: 1128-1134
Date deposited: 25/03/2011
ISSN (print): 0007-1145
ISSN (electronic): 1475-2662
Publisher: Cambridge University Press
URL: http://dx.doi.org/10.1017/S0007114508971324
DOI: 10.1017/S0007114508971324
Notes: CORRIGENDUM: The publishers regret that the author list in this paper was incomplete. The list of contributing authors should have read: Leigh M. Riby1*, Jennifer McLaughlin2, Deborah M. Riby3 and Cheryl Graham2 1Division of Psychology, Northumbria University, Northumberland Building, Newcastle upon Tyne NE1 8ST, UK 2Department of Psychology, Glasgow Caledonian University, UK 3Department of Psychology, Newcastle University, UK doi:10.1017/S0007114508971324, Published by Cambridge University Press, 1 April 2008
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