ePrints

Synthetic, structural and kinetic studies on the binding of cyclohexane-1,2-bis(4-methyl-3-thiosemicarbazone) to divalent metal ions (Co, Ni, Cu, Zn or Cd)

Lookup NU author(s): Professor William Clegg, Dr Ross Harrington, Professor Richard Henderson

Downloads

Full text for this publication is not currently held within this repository. Alternative links are provided below where available.

Abstract

The reactions of cyclohexane-1,2-bis(4-methyl-3-thiosemicarbazone) (CHMTSC) with MCl2 (M = Co, Ni, Cu or Zn) and Cd(NO3)(2) have been shown to produce complexes in which the thiosemicarbazone has been doubly deprotonated {[M(CHMTSC-2H(+))] (M = Co, Ni or Ni)}, analogous to those reported earlier with other Schiff base thiosemicarbazones. However, with ZnCl2 and Cd(NO3)(2), the complexes isolated are [ZnCl(CHMTSC)] Cl and [Cd(NO3)(CHMTSC)]NO3, containing the protonated forms of the ligand, which have been characterised by X-ray crystallography, as has free CHMTSC. The kinetics of the reactions between CHMTSC and all the various metal salts have been determined by stopped-flow spectrophotometry. In all cases, the reactions are complete on the seconds timescale. The reactions exhibit a first-order dependence on the concentration of metal salt and a first-order dependence on the concentration of CHMTSC. The thermodynamic and kinetic factors influencing the protonation state of the coordinated thiosemicarbazone are discussed.

Publication metadata

Author(s): Al-Karawi AJM, Clegg W, Harrington RW, Henderson RA

Publication type: Article

Publication status: Published

Journal: Dalton Transactions

Year: 2009

Issue: 3

Pages: 564-570

Print publication date: 01/01/2009

ISSN (print): 1477-9234

ISSN (electronic): 1477-9226

Publisher: Royal Society of Chemistry

URL: http://dx.doi.org/10.1039/b814852j

DOI: 10.1039/b814852j

Altmetrics

Share