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A New Approach to the Synthesis of 4-Hydroxyethylsulfonylstyrene

Lookup NU author(s): Dr Christophe Grosjean, Dr Alistair Henderson, Professor Allen Wright

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Abstract

A new, more environmentally benign route to hydroxyethylsulfonylstyrene has been developed, starting from 4-bromobenzenethiol, involving a solventless thioether formation, water-based perborate oxidation, and Suzuki-Miyaura cross coupling with a vinylborate reagent.

Publication metadata

Author(s): Grosjean C, Henderson AP, Herault D, Ilyashenko G, Knowles JP, Whiting A, Wright AR

Publication type: Article

Publication status: Published

Journal: Organic Process Research & Development

Year: 2009

Volume: 13

Issue: 3

Pages: 434-441

ISSN (print): 1083-6160

ISSN (electronic): 1520-586X

Publisher: American Chemical Society

URL: http://dx.doi.org/10.1021/op800292b

DOI: 10.1021/op800292b

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