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Lookup NU author(s): Dr David Woods
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Objective: To investigate the cause and nature of palpitations occurring at high altitude. Methods: Implantable loop recorders were inserted subcutaneously in the left pectoral region of 9 healthy male volunteers. Subjects flew to Kathmandu (1,250 m) and then Lukla (2,800 m) before immediately commencing an identical ascent and descent profile to high altitude. The loop recorders were activated with any episode of palpitations and during exercise, rest and sleep. Arterial oxygen saturation was assessed concomitant with device activation. Results: Above 5,000 m all subjects reported palpitations during exercise. All subjects demonstrated sinus tachycardia and marked sinus arrhythmia; one subject demonstrated atrial flutter; one subject had non-conducted p waves, and a further subject had marked ST segment depression. Conclusions: Significant arrhythmias occur at high altitude. In view of the increased risk of sudden cardiac death at high altitude, and considering that the elderly account for 15% of the 100 million visitors to altitude annually, further investigation is required. Copyright (c) 2008 S. Karger AG, Basel.
Author(s): Woods DR, Allen S, Betts TR, Gardiner D, Montgomery H, Morgan JM, Roberts PR
Publication type: Article
Publication status: Published
Journal: Cardiology
Year: 2008
Volume: 111
Issue: 4
Pages: 239-246
ISSN (print): 0008-6312
ISSN (electronic): 1421-9751
Publisher: S. Karger AG
URL: http://dx.doi.org/10.1159/000127445
DOI: 10.1159/000127445
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