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Adjuvant (post-surgery) chemotherapy for early stage epithelial ovarian cancer

Lookup NU author(s): Dr Heather Dickinson


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Epithelial ovarian cancer kills about 1700 in the UK each year. Ten to fifteen percent of all cases are diagnosed early when there is still a good chance of cure. The treatment of early stage disease involves surgery to remove disease often followed by chemotherapy. The largest clinical trials of this adjuvant therapy show an overall survival (OS) advantage with adjuvant platinum based chemotherapy but the precise role of this treatment in sub-groups of patients with differing prognoses needs to be defined.

Publication metadata

Author(s): Winter-Roach BA, Kitchener HC, Dickinson HO

Publication type: Review

Publication status: Published

Journal: Cochrane Database of Systematic Reviews

Year: 2009

Issue: 1

Pages: CD004706

ISSN (electronic): 1469-493X

Publisher: Update Software Ltd.


DOI: 10.1002/14651858.CD004706.pub2

Notes: Updated version of review published 2012: Winter-Roach BA, Kitchener HC, Lawrie TA. Adjuvant (post-surgery) chemotherapy for early stage epithelial ovarian cancer. Cochrane Database of Systematic Reviews 2012, Issue 3. Art. No.: CD004706. DOI: 10.1002/14651858.CD004706.pub4.