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Multiple convergence in polyketide biosynthesis: a third folding mode to the anthraquinone chrysophanol

Lookup NU author(s): Professor Michael Goodfellow

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Abstract

The polyketide chrysophanol is shown to be formed, in an organism-specific way, by a third folding mode, involving a remarkable cyclization of a bicyclic diketo precursor, thus establishing the first example of multiple convergence in polyketide biosynthesis.

Publication metadata

Author(s): Bringmann G, Gulder TAM, Hamm A, Goodfellow M, Fiedler HP

Publication type: Article

Publication status: Published

Journal: Chemical Communications

Year: 2009

Volume: 2009

Issue: 44

Pages: 6810-6812

ISSN (print): 1359-7345

ISSN (electronic): 1364-548X

Publisher: Royal Society of Chemistry

URL: http://dx.doi.org/10.1039/b910501h

DOI: 10.1039/b910501h

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