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The prevalence of osteoporosis in patients with severe hip and knee osteoarthritis awaiting joint arthroplasty

Lookup NU author(s): Elizabeth Lingard, Sheryl Mitchell, Emeritus Professor Roger Francis, David Rawlings, Professor Fraser Birrell, Professor Andrew McCaskie


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Objective: to determine the prevalence of osteoporosis among patients with osteoarthritis awaiting total knee arthroplasty or total hip arthroplasty aged between 65 and 80 years. Design: cross-sectional observational study. Setting: tertiary referral centre in Newcastle upon Tyne, UK. Subjects: patients with osteoarthritis awaiting total knee hip arthroplasty aged between 65 and 80 years. Methods: lumbar spine, bilateral femoral and forearm bone mineral density (BMD) measurements were obtained using dual-energy X-ray absorptiometry. Results: the cohort consisted of 199 patients with a mean age of 72 years (SD 4), and 113 (57%) were women. The overall rate of osteoporosis at any site was 23% (46/199) and a further 43% (85/199) of patients would have been classified as osteopaenic according to World Health Organization criteria. Osteoporosis was more commonly detected in the forearm (14%) than the lumbar spine (8.5%) and proximal femur of the index side (8.2%). Conclusions: in summary, a significant proportion of patients with end-stage OA have osteoporosis but this diagnosis may be missed unless BMD measurements are performed at sites distant from joints affected by OA.

Publication metadata

Author(s): Lingard EA, Mitchell SY, Francis RM, Rawlings D, Peaston R, Birrell FN, McCaskie AW

Publication type: Article

Publication status: Published

Journal: Age and Ageing

Year: 2010

Volume: 39

Issue: 2

Pages: 234-239

ISSN (print): 0002-0729

ISSN (electronic): 1468-2834

Publisher: Oxford University Press


DOI: 10.1093/ageing/afp222


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