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Lookup NU author(s): Professor David Elliott
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Nuclear RNA processing is a critical stage in eukaryotic gene expression, and is controlled in part by the expression and concentration of nuclear RNA-binding proteins. Different nuclear RNA-binding proteins are differentially expressed in different cells, helping the spliceosome to decode pre-mRNAs into alternatively spliced mRNAs. Recent post-genomic technology has exposed the complexity of nuclear RNA processing, and is starting to reveal the mechanisms and rules through which networks of RNA-binding proteins can regulate multiple parallel pathways. identification of multiple parallel processing pathways regulated by nuclear RNA-binding proteins is leading to a systems-wide understanding of the rules and consequences of alternative nuclear RNA processing.
Author(s): Liu YL, Elliott DJ
Publication type: Conference Proceedings (inc. Abstract)
Publication status: Published
Conference Name: Biochemical Society Transactions: 13th Tenovus Scotland Symposium - Gene Expression in Development and Disease
Year of Conference: 2010
Publisher: Portland Press Ltd.
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