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Efficacy of contraceptive methods: A review of the literature

Lookup NU author(s): Dr Diana Mansour


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Methods Medline and Embase were searched using the Ovid interface from January 1990 to February 2008, as well as the reference lists of published articles, to identify studies reporting contraceptive efficacy as a Pearl Index or life-table estimate. Reports that recruited less than 400 subjects per study group and those covering less than six cycles/six months were excluded. In addition, unlicensed products or those not internationally available, emergency contraception, and vasectomy studies were excluded. Results Information was identified and extracted from 139 studies. One-year Pearl Indices reported for short-acting user-dependent hormonal methods were generally less than 2.5. Gross life-table rates for long-acting hormonal methods (implants and the levonorgestrel releasing-intrauterine system [LNG-IUS]) generally ranged between 0-0.6 per 100 at one year, but wider ranges (0.1-1.5 per 100) were observed for the copper intrauterine devices (0.1-1.4 per 100 for Cu-IUDs with surface area >= 300 mm= 300 mm

Publication metadata

Author(s): Mansour D, Inki P, Gemzell-Danielsson K

Publication type: Review

Publication status: Published

Journal: The European Journal of Contraception and Reproductive Health Care

Year: 2010

Volume: 15

Issue: 1

Pages: 4-16

Print publication date: 01/02/2010

ISSN (print): 1362-5187

ISSN (electronic): 1473-0782


DOI: 10.3109/13625180903427675