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Simple urethral dilatation, endoscopic urethrotomy, and urethroplasty for urethral stricture disease in adult men

Lookup NU author(s): Dr Susan Wong, Rob Pickard


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Narrowing of the urine pipe (urethral stricture), is a common cause of problems passing water in younger men. Standard treatment consists of widening the strictured segment using instruments passed down the urethra (urethral dilatation or urethrotomy). Alternatively, a urethroplasty operation can be performed whereby the narrowed area is removed or replaced by graft material. Uncertainty as to which option is best prompted this review of current evidence. We found very little good quality evidence and were unable to achieve all review objectives. The results of a single study suggest that dilatation and urethrotomy offer equivalent outcomes but are associated with a high rate of recurrence of the stricture requiring repeated procedures over a relatively short period of time. Preliminary data reported in abstract form suggested that urethroplasty was more effective than urethrotomy for the specific circumstance of urethral trauma following fracture of the pelvic bones. We found no data concerning the well-being or quality of life amongst men treated for urethral stricture disease. The main conclusion of the review is that the current lack of quality evidence means that further trials are needed to establish which intervention is most effective and most cost-effective for treatment of urethral stricture disease in men.

Publication metadata

Author(s): Wong SSW, Narahari R, O'Riordan A, Pickard R

Publication type: Review

Publication status: Published

Journal: Cochrane Database of Systematic Reviews

Year: 2010

Issue: 4

Pages: CD006934

Print publication date: 14/04/2010

ISSN (electronic): 1469-493X

Publisher: Cochrane Database of Systematic Reviews 2010, Issue 4. Art. No.: CD006934.


DOI: 10.1002/14651858.CD008267