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Misinterpretation of randomised trial evidence: do antidepressants work?

Lookup NU author(s): Professor Hamish McAllister-WilliamsORCiD


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On February 29 this year I was due to give a talk about the pharmacological management of depression to a large meeting of psychiatrists. As my radio alarm clock came on I heard the top headline on the BBC Radio 4 Today programme ‘New study suggests that antidepressants don’t work’. The headline arose from a meta-analysis published by Irvine Kirsch, Professor of Psychology at the University of Hull, and colleagues (Kirsch et al, 2008).

Publication metadata

Author(s): McAllister-Williams RH

Publication type: Editorial

Publication status: Published

Journal: British Journal of Hospital Medicine

Year: 2009

Volume: 69

Issue: 5

Pages: 246-247

ISSN (print): 1750-8460

ISSN (electronic): 1759-7390

Publisher: Mark Allen Publishing Ltd.