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Lookup NU author(s): Emeritus Professor David Hendrick
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Always consider the possibility of an occupational cause at the time adult-onset asthma is first recognized-the probability of this is of the order 9-15%. Do not prescribe treatment unless this possibility is remote or the asthma is life-threatening. If the possibility is not remote seek immediate advice from a specialized centre, without prescribing masking medication and without curtailing usual work practice. The specialized referral centre should place the accurate measurement of airway responsiveness at the centre of investigatory strategies. A return-to-work study, monitored by serial measurements of airway responsiveness and ventilatory function, provides adequate objective evidence for diagnosis in most cases. When a novel cause is suspected, specific inhalation provocation testing with the particular agent in the specialized centre is desirable. Regular competent surveillance is necessary in high-risk occupational environments; this should include environmental monitoring, the detection of relevant new symptoms, spirometry measurements, serum antibody studies (where available) and a robust protocol for managing inevitable failed attendances.
Author(s): Hendrick DJ
Publication type: Article
Publication status: Published
Journal: British Medical Bulletin
Year: 2010
Volume: 95
Issue: 1
Pages: 175-192
Print publication date: 01/09/2010
ISSN (print): 0007-1420
ISSN (electronic): 1471-8391
Publisher: Oxford University Press
URL: http://dx.doi.org/10.1093/bmb/ldq021
DOI: 10.1093/bmb/ldq021
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