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Diabetes insipidus describes the excess production of dilute urine. It is caused by the lack of production or action of the hormone vasopressin, although primary polydipsia can produce similar symptoms. Diagnosis requires a targeted history and examination. Confirmation requires coordination through specialist services for appropriate investigation. Lack of vasopressin can be treated with synthetic vasopressin analogues. Additional approaches may be needed for some forms of the condition. Combined defects in vasopressin production and thirst perception require a bespoke approach involving a structured programme of fluid intake and antidiuresis.
Author(s): Ball S
Publication type: Article
Publication status: Published
Journal: Medicine
Year: 2009
Volume: 37
Issue: 8
Pages: 414-415
ISSN (print): 0304-5412
ISSN (electronic): 1578-8822
Publisher: Elsevier Doyma
URL: http://dx.doi.org/10.1016/j.mpmed.2009.05.014
DOI: 10.1016/j.mpmed.2009.05.014
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