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Changes in interstitial noradrenaline, trapezius muscle activity and oxygen saturation during low-load work and recovery

Lookup NU author(s): Dr Gerd Flodgren


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Both physical as well as mental demands result in an increased activity in the sympathetic nervous system (SNS) with changes in blood-pressure and heart-rate. Through local release of catecholamines, e.g. noradrenaline (NAd) SNS exerts various actions at the muscle level. The aims of this study were to investigate the effects of low-load repetitive work alone and in combination with mental demands on local muscle interstitial noradrenaline concentration [NAd]i, muscle activity and oxygenation, assessed with microdialysis, surface electromyography, and near-infrared spectroscopy, respectively. Healthy females (n = 15) were exposed to (1) 30 min repetitive work (RW) and (2) 30 min repetitive work with superimposed mental load (RWML) on two different occasions. Muscle [NAd]i and muscle activity increased significantly in response to RW, but did not increase further during RWML. For RW, [NAd]i was found to be inversely correlated to muscle activity. Oxygenation decreased significantly during work, independently of occasion. Our findings indicate that low-load work causes significantly increased trapezius muscle [NAd]i in healthy females, and short periods of superimposed mental load do not add to this increase and further, that both muscle activity and oxygenation were unaffected by the superimposed mental load. © Springer-Verlag 2009.

Publication metadata

Author(s): Flodgren G, Crenshaw A, Gref M, Fahlström M

Publication type: Article

Publication status: Published

Journal: European Journal of Applied Physiology

Year: 2009

Volume: 107

Issue: 1

Pages: 31-42

Print publication date: 01/01/2009

ISSN (print): 1439-6319

ISSN (electronic): 1439-6327

Publisher: Springer


DOI: 10.1007/s00421-009-1095-5

PubMed id: 19504120


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Funder referenceFunder name
Swedish Agency for Innovation Systems