Toggle Main Menu Toggle Search

Open Access padlockePrints

Are early infectious exposures involved in the etiology of childhood CNS tumors?

Lookup NU author(s): Dr Richard McNallyORCiD


Full text for this publication is not currently held within this repository. Alternative links are provided below where available.


Early infectious exposures have been implicated in the etiology of childhood CNS tumors. The article evaluated here assesses whether infectious exposure in the first years of life is involved by analyzing birth order, childcare attendance and seasonality of birth. The conclusion is that exposure to infectious disease in early childhood does not play an important role in the etiology of pediatric CNS tumors. It is noted that the measures used are only proxies for infectious exposures and, as such, may not accurately reflect the underlying infectious burden. Furthermore, this study is from the Nordic countries and from a later period than previous studies. Differences in patterns of exposure to infection may vary geographically between countries and may have changed over time. However, the authors have not excluded the possibility that a specific infectious agent is involved, and it is agreed here that future efforts should include a focus on a search for such an agent or agents, as well as formulating plausible, diagnostic-specific, mechanistic hypotheses.

Publication metadata

Author(s): McNally RJQ

Publication type: Article

Publication status: Published

Journal: Expert Review of Neurotherapeutics

Year: 2010

Volume: 10

Issue: 11

Pages: 1663-1665

Print publication date: 01/11/2010

ISSN (print): 1473-7175

ISSN (electronic): 1744-8360

Publisher: Expert Reviews


DOI: 10.1586/ERN.10.157


Altmetrics provided by Altmetric