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Utilizing the Second-Meal Effect in Type 2 Diabetes: Practical Use of a Soya-Yogurt Snack

Lookup NU author(s): Mei Chen, Dr Ana Jovanovic, Professor Roy Taylor


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OBJECTIVE - To evaluate the effect of a prebreakfast high protein snack upon postbreakfast hyperglycemia RESEARCH DESIGN AND METHODS - We studied 10 men and women with diet-and/or metformin controlled type 2 diabetes Metabolic changes after breakfast were compared between 2 days breakfast taken only and soya yogurt snack taken prior to breakfast RESULTS - There was a significant lower rise in plasma glucose on the snack day The incremental area under the glucose curve was 450 +/- 55 mmol min/l on the snack day compared with 699 99 mmol min/l on the control day (P = 0 013) The concentration of plasma free fatty acids immediately before breakfast correlated with the increment in plasma glucose (r = 0 50 P = 0 013) CONCLUSIONS - Consuming a high-protein prebreakfast snack results in almost 40% reduction of postprandial glucose increment The second meal effect can be applied simply and practically to improve postbreakfast hyperglycemia in people with type 2 diabetes

Publication metadata

Author(s): Chen MJ, Jovanovic A, Taylor R

Publication type: Article

Publication status: Published

Journal: Diabetes Care

Year: 2010

Volume: 33

Issue: 12

Pages: 2552-2554

Print publication date: 01/12/2010

ISSN (print): 0149-5992

ISSN (electronic): 1935-5548

Publisher: American Diabetes Association


DOI: 10.2337/dc10.0552


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Funder referenceFunder name
Newcastle National Institute for Health Research Biomedical Research Centre in Ageing
073561Wellcome Trust