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Lookup NU author(s): David Langton, Professor Tom Joyce, Dr Simon Jameson, Jane Lord
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We sought to establish the incidence of joint failure secondary to adverse reaction to metal debris (ARMD) following metal-on-metal hip resurfacing in a large, three surgeon, multicentre study involving 4226 hips with a follow-up of 10 to 142 months. Three implants were studied: the Articular Surface Replacement; the Birmingham Hip Resurfacing; and the Conserve Plus. Retrieved implants underwent analysis using a co-ordinate measuring machine to determine volumetric wear. There were 58 failures associated with ARMD. The median chromium and cobalt concentrations in the failed group were significantly higher than in the control group (p < 0.001). Survival analysis showed a failure rate in the patients with Articular Surface Replacement of 9.8% at five years, compared with < 1% at five years for the Conserve Plus and 1.5% at ten years for the Birmingham Hip Resurfacing. Two ARMD patients had relatively low wear of the retrieved components. Increased wear from the metal-on-metal bearing surface was associated with an increased rate of failure secondary to ARMD. However, the extent of tissue destruction at revision surgery did not appear to be dose-related to the volumetric wear.
Author(s): Langton DJ, Joyce TJ, Jameson SS, Lord J, Van Orsouw M, Holland JP, Nargol AVF, De Smet KA
Publication type: Article
Publication status: Published
Journal: Journal of Bone and Joint Surgery: British Volume
Year: 2011
Volume: 93B
Issue: 2
Pages: 164-171
Print publication date: 01/02/2011
ISSN (print): 0301-620X
Publisher: British Editorial Society of Bone and Joint Surgery
URL: http://dx.doi.org/10.1302/0301-620X.93B2.25099
DOI: 10.1302/0301-620X.93B2.25099
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